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Propagation of a single-reaction wave in a constant-density turbulent flow is studied by considering reaction rates that depend on the reaction progress variable c in a highly nonlinear manner. Analysis of Direct Numerical Simulation (DNS) data obtained recently from 26 reaction waves characterized by low Damköhler (0.01 < Da < 1) and high Karlovitz (6.5 < Ka < 587) numbers reveals the following

Background: Total tau (tTau) and phosphorylated 181P tau (pTau) are supportive diagnostic cerebrospinal fluid (CSF) biomarkers for Alzheimer's disease. Manual CSF tau assays are limited by lot-to-lot and between-laboratory variability and long incubation/turnaround times. Elecsys® Total-Tau CSF and Phospho-Tau (181P) CSF immunoassays were developed for fully automated cobas e analyzers, allowing b

Introduction: The standard therapy for exocrine pancreatic insufficiency (EPI) is porcine-derived pancreatic enzyme replacement therapy (PERT). In the present study we tested a new approach with a mixture of pancreatic- like enzymes of microbial origin (PLEM) in a 1-week efficacy study in EPI pigs. In addition to the conventionally used coefficient of fat and nitrogen absorption (CFA and CNA), par

The effect of mineral fertilization and its application pattern on microbial activity and the subsequent CO2 and CH4 emissions arising from soil organic matter (SOM) or added substrate remains unclear. We quantified the decomposition of 13C-labeled straw and the priming effect (PE) governed by the N and P fertilizer application pattern during a 100-day experiment in a flooded soil. Straw addition

Background: A healthy lifestyle has been shown to reduce the risk of coronary artery disease (CAD). The extent to which lifestyle influences the risk of CAD for people with pre-existing non-modifiable risk factors is less studied. We therefore examined the associations between a favorable lifestyle and incidence of CAD in population subgroups based on gender, age, educational level, and parental h

This thesis asks when and why interest groups influence political parties. I address this question in two ways: 1) by examining the organizational ties between parties and interest groups, given that party-interest group ties may constitute an important step on groups' way to influence, and 2) by more directly examining interest group influence on parties. By doing this, the thesis contributes to

The idea of this special issue on Spoken language in time and across time emerged at an international symposium on this topic that we organised at Lund University on 20 September 2019. The purpose of the symposium was to celebrate important past and present achievements of spoken language research as well as past and present corpora available for such research. Some speakers reported on academic a

Heterogeneous patterns of genomic differentiation are commonly documented between closely related populations and there is considerable interest in identifying factors that contribute to their formation. These factors could include genomic features (e.g., areas of low recombination) that promote processes like linked selection (positive or purifying selection that affects linked neutral sites) at

The “nutmeg lung pattern” on fetal magnetic resonance imaging (MRI) indicates pulmonary lymphangiectasia. This is associated with adverse outcomes, particularly in fetuses with congenital heart defects and impaired pulmonary venous return. Whereas lymphedema is common in fetuses with Turner syndrome, pulmonary lymphangiectasia is not. A 26-year-old woman presented with a fetus with hypoplastic lef

PURPOSE: Self-management has increased in recognition in stroke research and rehabilitation along with growing trends of shorter hospital stays and more patient-centred care. Family members are key persons in the self-management process, but their views and experiences of self-management have not been studied in detail. This study aimed to explore family members' understanding of self-management,

Are incumbent cabinets favored when a new government forms in parliamentary democracies? This article develops and evaluates a new hypothesis on the so-called incumbency advantage in government formation which stresses the role of interpersonal relations in coalition bargaining. We propose that the Prime Minister (PM) plays a particularly important role in bargaining and suggest that when the PM i

Resource competition between wild pollinators and managed honeybees (Apis mellifera) has the potential to detrimentally impact insect biodiversity as well as wild plant and crop pollination. As honeybees are central place foragers, their competitive impact on wild bees is expected to be structured by hive proximity, in conjunction with foraging decisions related to landscape-level resource availab

The removal of organic micropollutants in granular activated carbon (GAC) filters can be attributed to adsorption and biological degradation. These two processes can interact with each other or proceed independently. To illustrate the differences in their interaction, three 14C-labeled organic micropollutants with varying potentials for adsorption and biodegradation were selected to study their ad

Conservation biological control of crop pests by natural enemies relies on management strategies to favour their trophic interactions. In agricultural landscapes, natural enemies acting across habitat boundaries may feed on non-pest prey, resulting in apparent competition between non-pest prey and pests. Such communities, including pests, non-pest prey, and natural enemies have been shown to be af

Background: We investigated all-cause and epilepsy-related mortality in patients operated with resective epilepsy surgery and in non-operated patients with drug-resistant epilepsy. Our hypothesis was that patients who proceed to surgery have lower mortality over time compared with non-operated patients. Method: Data from 1329 adults and children from the Swedish National Epilepsy Surgery Register

Polypharmacy increases the risk of drug-drug interactions that may disturb treatment effects. The aim of this study was to investigate the frequency of codispensing of potentially interacting or contraindicated drugs related to PH-specific treatment in the Swedish pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) population. All prescribed drugs, on an

Postural orthostatic tachycardia syndrome (POTS) is a cardiovascular autonomic disorder characterized by excessive heart rate increase on standing, leading to debilitating symptoms with limited therapeutic possibilities. Proteomics is a large-scale study of proteins that enables a systematic unbiased view on disease and health, allowing stratification of patients based on their protein background.

BACKGROUND. Neoantigen-driven recognition and T cell–mediated killing contribute to tumor clearance following adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TILs). Yet how diversity, frequency, and persistence of expanded neoepitope-specific CD8+ T cells derived from TIL infusion products affect patient outcome is not fully determined. METHODS. Using barcoded pMHC multimers, we p

In times of emergent emphases on how climate change will affect welfare societies, welfare policies and individuals’ welfare and vice versa, this study investigates public support for welfare and environmental policies and concerns. Since previous research and literature have pointed towards a socioeconomic divide between the welfare agenda and the environmental agenda in terms of public support,