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Background: Most validations of paediatric glomerular filtration rate (GFR) estimating equations using standardized creatinine (CR) and cystatin C (CYS) assays have comprised relatively small cohorts, which makes accuracy across subgroups of GFR, age, body mass index (BMI) and gender uncertain. To overcome this, a large cohort of children referred for GFR determination has been established from se

BACKGROUND: Beans are rich and inexpensive sources of proteins and carbohydrates around the world, but particularly in developing countries. However, many legume varieties are still underutilized. In this study, physical characteristics of the seeds of three Phaseolus lunatus cultivars were characterized. Also, the chemical composition and starch digestibility in the cooked beans were assessed. RE

BACKGROUND: Tortillas were prepared from two (blue and regular white) maize varieties and compared with regard to chemical composition and in vitro starch digestibility, i.e., available starch (AS), total (RS) and retrograde (RRS) resistant starch contents, amylolysis rate and predicted glycemic index (pGI). The impact of cold storage (4°C) on digestibility was also investigated. RESULTS: Despite

If, as indicated by some studies, prudent diets such as the Mediterranean or DASH diets can be further improved, an evolutionary approach may be helpful. Paleolithic diets represent the food habits during more than two million years of hominid and human evolution before the development of agriculture. Fruits, tubers, nuts, lean meat, larvae, insects, fish, shellfish, eggs, honey, and a large varie

This study investigates the relationship between grain-size distributions and sediment transport processes at Ängelholm Beach in southwest Sweden. In total, 308 longshore and cross-shore distributed sediment samples are analysed with respect to median grain size and sorting. The longshore sediment transport is almost unidirectional from north to south. Its gradients cause erosion in the north and

Background: The COVID-19 pandemic accelerated the use of telemedicine, specifically video consultations as they provide healthcare access in challenging situations where face-to-face encounters are not possible. Nevertheless, it remains largely unknown to what extent the organisation of general practice and national digital infrastructures have impacted the uptake and use of video consultations. O

Radicalization is most often seen as a gradual process that may or may not lead to radical or extreme behaviors such as terrorism. Theories on the radicalization process often highlight the potential role of social exclusion in the propensity for radicalization. We here present some of the major radicalization theories and discuss exclusion as a common denominator that could trigger a radicalizati

Water structure is crucially important to protein function and catalysis and can be conserved throughout related proteins despite differences in sequence. The complex hydrogen-bonding networks formed by water molecules and protein residues have been studied extensively, and graph-theory-based methods have frequently been used to describe these networks. Although there exist a number of tools which

We report measurements of the production of prompt D0, D+, D*+ and Ds + mesons in Pb–Pb collisions at the centre-of-mass energy per nucleon-nucleon pair sNN=5.02 TeV, in the centrality classes 0–10%, 30–50% and 60–80%. The D-meson production yields are measured at mid-rapidity (|y| < 0.5) as a function of transverse momentum (pT). The pT intervals covered in central collisions are: 1 < pT< 50 GeV/

It is important to study the factors affecting estimates of wetness since wetness is crucial in climate change studies. The availability of digital elevation models (DEMs) generated with high resolution data is increasing, and their use is expanding. LIDAR earth elevation data have been used to create several DEMs with different resolutions, using various interpolation parameters, in order to comp

Biological and physical retrospective dosimetry are recognised as key techniques to provide individual estimates of dose following unplanned exposures to ionising radiation. Whilst there has been a relatively large amount of recent development in the biological and physical procedures, development of statistical analysis techniques has failed to keep pace. The aim of this paper is to review the cu

Background: Patients diagnosed with oesophageal and gastric cancer face a poor prognosis and numerous challenges of symptom management, lifestyle adjustments and complex treatment regimens. The multifaceted care needs and rapid disease progression reinforce the need for proactive and coherent health care. According to the national cancer strategy, providing coherent health care and palliative supp

Many public sector managers and professionals perceive performance measurement as an administrative burden with limited benefits. Numbers are collected for other people's purposes. At worst, poorly incentivized indicators force managers and professionals to take actions that go against the overall objectives of the organization. Professionals in sectors such as healthcare, education and social ser

BACKGROUND: Chronic subdural hematoma (CSDH) is one of the most common neurosurgical diseases. In surgical management of CSDH, there is a lack of standardized guidelines concerning surgical techniques and a lack of consensus on which technique(s) are optimal. Neurosurgical centers have shown a wide variation in surgical techniques. The purpose of this study was to compare two different surgical te

BackgroundTransfusion of allogeneic blood influences outcome after surgery. Despite widespread availability of transfusion guidelines, transfusion practices might vary among physicians, departments, hospitals and countries. Our aim was to determine the amount of packed red blood cells (pRBC) and blood products transfused intraoperatively, and to describe factors determining transfusion throughout

The germ theory states that pathogenic microorganisms are responsible for causing infectious diseases. The theory is inherently microbe-centric and does not account for variability in disease severity among individuals and asymptomatic carriership—two phenomena indicating an important role for host variability in infection outcome. The basic tenet of the germ theory was recently challenged, and a

Externally bonded fiber-reinforced polymer (FRP) plates or sheets have become a common retrofitting approach for sustaining old reinforced concrete structures in the modern era. The capacity of FRP-strengthened structures cannot be accurately estimated because the bond strength between FRP and concrete surface is accurately unpredictable. Various studies are available in the literature to predict

To make glomerular filtration rate (GFR) estimating equations applicable across populations with different creatinine generation by using rescaled serum creatinine (sCr/Q) where sCr represents the individual creatinine level and Q the average creatinine value in healthy persons of the same population. GFR measurements (mGFR, plasma clearance of 51Cr-EDTA) were conducted in 964 adult Black European