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Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death

Induction of the mitochondrial permeability transition (MPT) has been implicated in cellular apoptosis and in ischemia-reperfusion injury. During MPT, a channel in the inner mitochondrial membrane, the mitochondrial megachannel, opens and causes isolated mitochondria to swell. MPT and mitochondrial swelling is inhibited by cyclosporin A (CsA), which may also inhibit apoptosis in some cells. Treatm

Increased glomerular permeability to negatively charged Ficoll relative to neutral Ficoll in rats.

It is established that the glomerular filter sieves macromolecules based on their size, shape, and charge. Anionic proteins are thus retarded compared with their neutral or cationic counterparts. However, recent studies have indicated that charge effects are small, or even "anomalous," for polysaccharides. We therefore investigated the impact of charge on the glomerular permeability to polysacchar

Accounting for depressive symptoms in women: a twin study of associations with interpersonal relationships

Background: This study examined how interpersonal relationships, specifically marital quality and adequacy of social support, are associated with depressive symptoms among women. Methods: A sample of 326 female monozygotic and dizygotic twin pairs and their spouses was drawn from the Swedish Twin Registry. Associations among the three variables were evaluated by comparing similarities among monozy

SWEDEN: Integrated strategies to overcome market barriers.

A national debate about how to transform and to ‘green’ the problematic housing stocks from the boom era has been going on since the late 1990s. Different kinds of policy instruments with energy efficiency objectives that address either energy systems, energy sources or construction and renovation of the building envelope have been in use. Some policy instruments have combined green objectives wit

Through the eyes of a woodpecker: Understanding habitat selection, territory quality and reproductive decisions from individual behaviour

Popular Abstract in Swedish Med hackspettsögon: att förstå habitatval, revirkvalitet och reproduktionsbeslut utifrån individers beteende Min doktorsavhandling bygger både på teoretiska modeller och på fältstudier av mindre hackspett (Dendrocopos minor). För att slippa språkliga krumbukter eller tvetydigheter kommer jag hädanefter att kalla arten "småspett" i denna sammanfattning. Fältstudierna gjIn this thesis I present some connections between foraging behaviour and reproductive success, time budget, tree species use, and habitat selection. The thesis is based upon both theoretical and empirical work. All empirical studies concern a south Swedish population of lesser spotted woodpeckers Dendrocopos minor, studied between 1990 and 1996. The foraging behaviour of the lesser spotted woodpe

Effects of future climate on carbon assimilation of boreal Norway spruce

Popular Abstract in Swedish Det norra barrskogsbältet, även kallat de boreala skogarna, sträcker sig runt hela norra halvklotet. Det utgör en tredjedel av den globala skogsytan, och innehåller hälften av den totala mängden kol finns lagrat i samtliga skogsekosystem. Trots de låga temperaturerna, den korta vegetationssäsongen och en liten mängd inkommande solenergi under året, är dessa ekosystem viIn boreal forests, the main factors limiting biomass production are the harsh climate, which combines a short growing season and low annual levels of incoming solar energy, and the limited availability of nitrogen. These limitations will be directly affected by climate change, and may in turn substantially affect the carbon budget of the boreal forests, the production of wood and biofuel, biodiver

Acceptable noise level: Repeatability with Danish and non-semantic speech materials for adults with normal hearing

Objective: The acceptable noise level (ANL) is used to quantify the amount of background noise that subjects can accept while listening to speech, and is suggested for prediction of individual hearing-aid use. The aim of this study was to assess the repeatability of the ANL measured in normal-hearing subjects using running Danish and non-semantic speech materials as stimuli and modulated speech-sp

Carbon addition alters vegetation composition on ex-arable fields

1. Recent changes in European agricultural policy have led to measures to reverse the loss of species-rich grasslands through the creation of new areas on ex-arable land. Ex-arable soils are often characterized by high inorganic nitrogen (N) levels, which lead to the rapid establishment of annual and fast-growing perennial species during the initial phase of habitat creation. The addition of carbo

More than just a label: The impact of the vegan label on product perception and consumption intentions across health consciousness levels

Purpose: The study aims to examine whether health consciousness, as a cognitive heuristic, influences the impact of vegan labels, as external cues, on product attribute perceptions such as taste, health, and environmental friendliness, as well as on consumption intentions. As consumers face cognitive limitations when evaluating food products, this research aim to contribute to the understanding of

Effekten av information om korta tåg på passagerarbeteende och påstigningstider: En studie vid Lund C

I pendeltågstrafiken körs ibland tåg med färre vagnar än normalt (så kallade korta tåg). Detta kan påverka hur passagerarna sprider ut sig på plattformen och hur snabbt påstigningen går. Syftet med detta examensarbete är att undersöka effekten av reseinformation om korta tågsammansättningar (tåg med 4 dörrar) på passagerares beteende på plattformen och påstigningstider, med fokus på Lunds centralsIn commuter train traffic, trains sometimes run with fewer carriages than normal (short trains). This can affect how passengers spread out on the platform and how quickly they can board. The purpose of this thesis is to investigate how travel information about short train formations (trains with 4 doors) affects passenger behavior on the platform and boarding times. The study focuses on Lund Centr

More than just a label: The impact of the vegan label on product perception and consumption intentions across health consciousness levels A quantitative study in the food industry

Purpose: The study aims to examine whether health consciousness, as a cognitive heuristic, influences the impact of vegan labels, as external cues, on product attribute perceptions such as taste, health, and environmental friendliness, as well as on consumption intentions. As consumers face cognitive limitations when evaluating food products, this research aim to contribute to the understandin

Finding ways of optimizing coagulant dosage, for a more sustainable wastewater treatment process

Maskininlärning kan liknas vid en student som läser en väldigt stor kurs med ett väldigt brett innehåll. När tentan börjar närma sig så inser studenten att det är omöjligt att tentaplugga genom att lära sig allt som står i kurslitteraturen. Så istället fokuserar hen på att göra extentor för att lära dig svara på de frågor som brukar komma på tentan. För varje extenta så svarar studenten på frågornThe wastewater treatment process at Oatly consists of several treatment steps of which, two are chemical treatment steps involving coagulation followed by flotation to remove phosphorous and COD. The coagulant dosage is mainly determined based on the operator’s experience and supported using results from jar tests. Jar tests are, however, highly dependent on the wastewater quality parameters maki

Expressing deference and intimacy concurrently with honorifics

This study is about ssu, a potential norm breaking honorific which reportedly can express intimacy and deference concurrently. While expressing intimacy and deference concurrently is incompatible with Brown and Levinson’s (1978 as cited in Hasegawa, 2015) politeness theory, Hasegawa (2015) provides a modification of their theory that allows for it. Yet, an honorific in hyōjungo ‘standard Japanese’

Språkförmåga och tidigare språkprestationers prediktiva värde vid inlärning av ett främmande språk

Syfte. Studien syftade till att undersöka om tidigare språkförmåga och språkprestationer, mätt med tre deltest, kan predicera inlärning av ett nytt språk. Vidare undersöktes relationen mellan vardera deltest samt deltagarnas utbildningsnivå i relation till resultatet. Metod. 45 vuxna deltagare rekryterades till studien. Llama B och Llama D användes som mått på språkprestation och LexTALE som mått Purpose. This study aimed to investigate whether general language abilities and previous language experience, measured by three tests, can predict the learning of a new language. Furthermore, the relationship between each test was investigated and the participants’ level of education was examined in relation to learning performance. Method. 45 adult participants were recruited for this study. Llam

#MeToo, Men’s Sexual Violence against Women and the Chilling Effect of Defamation Lawsuits: A Feminist Critique of the Swedish Criminal Justice System

#MeToo became in 2017 a strong and successful movement in Sweden where women exercised their freedom of expression to question structural injustice and men’s sexual violence against women. The movement broke the silence and stigma about being victim of men’s sexual violence and helped fight impunity. However, some of the #MeToo women in Sweden who told their stories also pointed out their perpetra

Social Capital Influence on Climate Change Mitigation Policies

For successful government implementation of climate change mitigation policies, public support is necessary to make these policies as effective as possible. Climate change requires collective action to reduce greenhouse gases currently emitted. Two factors have been suggested to have an important influence on support for policy implementation and climate policies: social capital, and risk percepti

Modellering och driftoptimering av laststyrning i fjärrvärmesystem

Värmebehov är beroende av rådande temperatur och väder samt kunders förbrukningsmönster. Detta ger upphov till varierande fjärrvärmelast och en konsekvent mer komplicerad värmeproduktion. Denna studie har undersökt potentialen för laststyrning, då byggnader utnyttjas som värmelager under kortare tid. Arbetet har fokuserat på modellering och utveckling av styrregler för laststyrningsmodellen samt iHeat load is dependent on outside temperature and weather as well as consumer habits. This leads to a variation in heat load and consequently a more complicated production. This study investigated the potential of demand side management, using load shifting and utilizing buildings for thermal storage. The work focused on modelling and developing operating conditions as well as implementation in di

Grön företagsanalys - Ett ramverk för utvärdering av miljöintegrering

Purpose: To develop a model, questions and criteria that can be used to assess and benchmark the environmental management performance of firms. Delimitations: An evaluation is not supposed to take more than two weeks to conduct and prerequisites the companies’ full cooperation. Methods: Qualitative and quantitative data was collected from interviews, internal documents and literature studies to de