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Cystatins are natural inhibitors of papain-like (family C1) and legumain-related (family C13) cysteine peptidases. Cystatin D is a type 2 cystatin, a secreted inhibitor found in human saliva and tear fluid. Compared to its homologues, cystatin D presents an unusual inhibition profile with a preferential inhibition cathepsin S > cathepsin H > cathepsin L, and no inhibition of cathepsin B or pig leg

Inflammatory responses play a vital role at different stages of colorectal carcinogenesis. C-type lectins mediate inflammatory/immune responses and participate in immune escape of pathogens and tumors. Our study aimed to evaluate the correlation between polymorphisms in three C-type lectin genes, CD209, MBL2 and REG4, and colorectal cancer (CRC) risk and clinical outcome. We genotyped 15 potential

This thesis proposes a machine-learning-supported pipeline which, put together, provides an estimate of roof surface area for solar panel installation. This pipeline is comprised of roof segmentation based on images and digital surface models and provides subsequent identification of key measurements such as roof length, roof width and roof angle. Obstacles belonging to a roof are also identified

In Zambia recent socio-economic changes are placing an undue burden on the elderly. The burden is greatly associated with the HIV and AIDS epidemic, which has led to increased mortality of prime aged adults. As a result of this the elderly are called upon to shoulder the responsibility of the family, as they become the principal caregivers for young children. The traditional family roles are being

Rooted in the environmental movement, the climate movement in Sweden is on the rise and increasingly gaining support in its fight against climate change and its unequal impacts. If successful, the movement can play an important role in changing society. There is increased awareness and proof of the gendered effects of climate change, but awareness of the role of gender in the climate movement seem

National laws and regulations on service delivery systems (SDS) for assistive technology (AT) in Europe aim to support the activity and participation of people with disabilities. The aim of this paper was to study similarities and differences in the SDS for AT of one Eastern and one Western EU member state. The legislation and regulations, and their operationalization were described from the persp

Background: With an increased life expectancy for the general population as well as for those ageing with chronic diseases, there are major challenges to the affected individuals and their families, but also to health care and societal planning. Most important, an increasing proportion of older people remain living in their ordinary homes despite health decline and disability. However, little is k

OBJECTIVE: People with disabilities find it harder to enter the labour market than people without disabilities and those with a mental illness are, in relation to people with other disabilities, employed at an essentially lower extent. Many are effectively helped by the vocational rehabilitation model Individual Placement and Support (IPS), but there are still many individuals left in undesired un

Understanding the land use history has proven crucial for the conservation of biodiversity in the agricultural landscape. In southern Sweden, very small and fragmented areas of the disturbance-dependent habitat xeric sand calcareous grassland support a large number of threatened and rare plants and animals. In order to find out if historical land use could explain variation in present-day habitat

This thesis consists of an introduction and four self-contained chapters that address issues of how organizations and institutions should be designed in order to provide adequate incentives and enable coordination. The first essay uses a multi-task principal-agent model to examine two reasons why coordination problems are common when public sector organizations share responsibilities: the incenti

Activities with the aim to assess the effects of ISA on driver behaviour through experimental research were carried out. In order to investigate the regional differences in effects on driver behaviour when driving with ISA field trials were set up in Hungary and Spain. Complementary results were added from the Belgian ISA field trials. To investigate the effects on driver behaviour from different

Why are sensory signals and motor command signals combined in the neurons of origin of the spinocerebellar pathways and why are the granule cells that receive this input thresholded with respect to their spike output? In this paper, we synthesize a number of findings into a new hypothesis for how the spinocerebellar systems and the cerebellar cortex can interact to support coordination of our mult

Expression of human leukocyte antigen (HLA) class II molecules on islet endothelial cells is a central vascular event in the pathogenesis of Type 1 diabetes. Previous studies demonstrated the ability of other vascular endothelial cells to express HLA and thereby to process islet autoantigens on their surface. We investigated whether the HLA-DQ2/8 genotype, which confers the highest risk for Type 1

In the 1990s, two randomised clinical trials started in Scandinavia addressing whether hormone replacement therapy (HRT) is safe for women with previous breast cancer. We report the findings of the safety analysis in HABITS (hormonal replacement therapy after breast cancer-is it safe?), an open randomised clinical trial with allocation to either HRT or best treatment without hormones. The main end

Stereoselective baker's yeast-catalysed bioreduction of bicyclo [2.2.2]octane-2.6-dione generates (1R, 4S, 6S)-6-hydroxy-bicyclo [2.2.2]octane-2-one (endo-alcohol) with high enantiomeric and diastereomeric excess. In contrast, whole cells and crude membrane fractions of Candida sp. have been reported to produce the unusual (I R, 4S, 6S)-diastereomer (exo-alcohol) as a major product. Previous in si

In physical therapy the clinical assessment Body Awareness Scale-Health (BAS-H) focusing on the quality of movements and movement behaviour has previously been studied for validity. The aim of this study was to address the inter-rater reliability and test-retest reliability in three groups. The groups assessed were: patients in psychiatric care with eating disorders (n = 26), patients in rehabilit

A gastrostomy device is removed from the gastrostoma when no longer needed. The aim of the study was to test the hypothesis of whether it is possible for the surgeon to decide which stoma has to be closed with a gastroraphy and which to leave for a spontaneous closure within a reasonable period of time. Out of a cohort of 321 patients, who had been operated with a video-assisted gastrostomy, we in

SCHEMA 20110322 SCHEMA 20160125 Schema för MVEN11 metodik och praktik, 16 hp vt 16 Kurstid: 18 januari – 28 mars 2016 Kursansvarig: Högni Hansson 0721-555648, hogni.hansson@cec.lu.se Introduktion: måndagen den 18 januari 2016, Ekologihuset M (Maskrosen), kl. 10.15-12.00 Lärare: HH Högni Hansson hogni.hansson@cec.lu.se JW john.winglander@infosoc.se LL Leif Lövström leif.loevstroem@spray.se AB Ander

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mven11_v2.pdf - 2026-05-08