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We have applied surface-enhanced ellipsometry contrast (SEEC) imaging for time-resolved label-free visualization of biomolecular recognition events on spatially heterogeneous supported lipid bilayers (SLB). Using a conventional inverted microscope equipped with total internal reflection (TIR) illumination, biomolecular binding events were monitored with a lateral resolution near the optical diffra

Having kin and living together with kin influence the individual life course, including a person’s marriage, reproductive career, and survival. A wide range of mechanisms are involved in connecting these life course transitions to support and competition between kin, as well as to characteristics of the family environment. How kin affect the life course is perceived differently in evolutionary ant

Objective: The soluble urokinase plasminogen activator receptor (suPAR) has potential as a prognosis and severity biomarker in several inflammatory and infectious diseases. In a previous cross-sectional study, suPAR levels were shown to reflect damage accrual in cases of systemic lupus erythematosus (SLE). Herein, we evaluated suPAR as a predictor of future organ damage in recent-onset SLE. Method

Background: Today, patient self-determination has become an issue in many western countries due to the widespread availability and use of technology, which makes it possible to prolong life often in spite of severe disability and poor quality of life. Many people fear an overzealous use of modern life-saying procedures which merely serve to prolong the dying process. As a first step towards autono

The amount and quality of greenness in the local outdoor environment has repeatedly been linked to human well-being. Different types of green areas are likely required in order to meet the various needs of people throughout the course of their lives and with regard to individual social and economic living conditions. The aim of the present study was to increase the understanding of different pathw

PURPOSE: miRNAs play a prominent role in a variety of physiologic and pathologic biologic processes, including cancer. For rectal cancers, only limited data are available on miRNA expression profiles, whereas the underlying genomic and transcriptomic aberrations have been firmly established. We therefore, aimed to comprehensively map the miRNA expression patterns of this disease. EXPERIMENTAL DE

Objective: To determine the within- and between-patient variability in the concentrations of synovial fluid, serum and urine markers of joint tissue metabolism in a cohort of patients with knee pain and cartilage changes consistent with early-stage knee osteoarthritis. Design: Samples of synovial fluid, serum, and urine were obtained from 52 patients on eight different occasions during 1 year, as

Objectives. The treatment of eating disorders is a complex process that relies not only on the use of psychotropic drugs but should include also nutritional counselling, psychotherapy and the treatment of the medical complications, where they are present. In this review recommendations for the pharmacological treatment of eating disorders (anorexia nervosa (AN), bulimia nervosa (BN), binge eating

The metabolite produced by one enzyme in a metabolic pathway can be transferred to the next enzyme in the pathway by free diffusion via solution or by channelling in an enzyme-enzyme complex without prior release of the metabolite to solution. While metabolite channelling is known to occur in systems where stable multienzyme complexes form, conflicting views have been expressed as to its existence

The paper reports a project conducted within the framework of the National Library of Sweden's Expert Group on Library Statistics. The project is financed by the National Library of Sweden, and it aims to capture how library managements make use of the current library statistics (based on the ISO-standard) in the decision-making process. Questions are also asked about the quality and usefulness of

Objectives: The strategies used to support smoking cessation among quitters were investigated according to year of smoking cessation and sociodemographic characteristics. Methods: The 2004 public health survey in Skane, Sweden, is a cross-sectional study. A total of 27 757 people aged 18-80 answered a postal questionnaire. The participation rate was 59%. Different strategies to support smoking ces

Herbivory is an important part of most ecosystems, and grazing alone can have a considerable impact on the ecosystems carbon balance with both direct and indirect effects. Removal of above-ground biomass by consumption of herbivores will change the below-ground carbon stock; the reduction of litter that goes into the ground will influence the total ecosystem carbon content. Little is however known

Background-Late mortality after repair of total anomalous pulmonary venous connection is frequently associated with pulmonary venous obstruction (PVO). We aimed to describe the morphological spectrum of total anomalous pulmonary venous connection and identify risk factors for death and postoperative PVO. Methods and Results-We conducted a retrospective, international, collaborative, population-bas

Background: Meniscus extrusion or hypertrophy may occur in knee osteoarthritis (OA). However, currently no data are available on the position and size of the meniscus in asymptomatic men and women with normal meniscus integrity. Methods: Three-dimensional coronal DESSwe MRIs were used to segment and quantitatively measure the size and position of the medial and lateral menisci, and their correlati

Understanding the land use history has proven crucial for the conservation of biodiversity in the agricultural landscape. In southern Sweden, very small and fragmented areas of the disturbance-dependent habitat xeric sand calcareous grassland support a large number of threatened and rare plants and animals. In order to find out if historical land use could explain variation in present-day habitat

Servicizing is a business model that holds the potential to support a shift towards more sustainable production and consumption by selling to the consumer the product's function, rather than the material product itself. This can offer direct environmental benefits by reducing the material and energy intensity of market transactions. Servicizing based business offers are starting emerging on the ma

Popular Abstract in English Labour is said to be obstructed when the baby’s presenting part fails to descend through the birth canal despite strong uterine contractions. Obstructed labour is one of the major causes of maternal and neonatal mortality and morbidity in low-income countries. It is mostly caused by disproportion between the baby’s head and mother’s pelvis but also abnormal presentationLabour is said to be obstructed when the presenting part fails to descend through the birth canal despite strong uterine contractions. The condition is mostly prevalent in low-income countries where the main causes are cephalopelvic disproportion and malpresentation. The overall aim of this thesis was to investigate the individual, community and health system factors associated with obstructed lab

Background and Purpose-Patients treated with oral anticoagulants (ACs) have an increased risk of intracerebral hemorrhage (ICH), which is more often fatal than spontaneous ICH. Options to reverse the AC effect include intravenous administration of vitamin K, plasma, and coagulation factor concentrate. However, the optimal management of AC-related ICH has not been determined in any randomized trial

Background: Oxidative stress is implicated in the pathogenesis of several complications of prematurity. The glutathione cycle is one of the most important intracellular antioxidant systems. The synthesis of glutathione may not be adequate in preterm neonates because of the low levels of cysteine available. The aim of this study was to evaluate cysteine and glutathione metabolism during the first w

Malignant fibrous histiocytoma (MFH) and fibrosarcoma (FS) of bone are rare malignant tumours and contentious entities. Sixty seven cases labelled as bone MFH (57) and bone FS (10) were retrieved from five bone tumour referral centres and reviewed to determine whether recent advances allowed for reclassification and identification of histological subgroups with distinct clinical behaviour. A panel