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Study objective: We evaluate the diagnostic accuracy of a high-sensitivity cardiac troponin T (hs-cTnT) level less than 5 ng/L or less than or equal to 14 ng/L at emergency department (ED) presentation, combined with the emergency physician's assessment of history and ECG, for ruling out major adverse cardiac events within 30 days. Methods: This prospective observational study enrolled consecutive

Risk factors of stroke/thromboembolism (TE) and major bleeding, and incidence of these events in specific age categories in warfarin-treated patients with mechanical heart valves (MHV) are uncertain. Our objective was to calculate event rates in specific age categories and identify risk factors for adverse events. Methods and results We identified 4,810 treatment periods with MHV between January 2

The screenplay written by Italian screenwriter and film director Massimo Franciosa in 1995 andfreely based on the short story Checchina’s virtue (1884) by Italian novelist and journalist MatildeSerao (1856-1927) is an example of those submedia ”designed especially to be transmediated”,according to Elleström (2014, 26). The transmediation never occurred however, since the filmnever came into being,

Parents react differently after their child is diagnosed with type 1 diabetes, both at onset and longitudinally. The aim of this study was to describe and compare the disease impact on parents, in terms of health-related quality of life (HRQOL), parents’ satisfaction with the care received, and the child´s experience of diabetes-specific family support 2 years after the child’s diagnosis. A furthe

Background: Risky consumption of alcohol is a global problem. More than 3.3 million deaths annually are associated with risky use of alcohol, and global alcohol consumption continues to increase. People who have high alcohol consumption often require planned and emergency surgical procedures. Risky drinking is associated with increased postoperative complications such as infections, cardiopulmonar

Kognitiva och emotionella svårigheter är vanliga hos personer som överlevt ett hjärtstopp. Rutinerna för uppföljning efter hjärtstopp varierar stort mellan olika regioner och sjukhus i Sverige.För att förbättra vården har Svenska HLR-rådets arbetsgrupp för vård efter hjärtstopp tagit fram svenska riktlinjer för uppföljning efter hjärtstopp. According to previous research, a structured cardiac arrest follow-up may contribute to identifying health problems and the potential need of support among survivors and their relatives. However, a survey on post CA care and follow-up in Sweden, reported a lack of structure and major variations among Swedish hospitals. In 2016, Swedish guidelines were published with the aim to improve care. Accord

Background: The contribution of smoking to rheumatoid arthritis (RA) is hypothesized to be mediated through formation of anti-citrullinated protein antibodies (ACPA). In RA, however, autoantibodies such as ACPA, rheumatoid factor (RF), and anti-carbamylated protein antibodies (anti-CarP) often occur together, and it is thus unclear whether smoking is specifically associated with some autoantibodie

BACKGROUND: Emerging evidence from cohort studies indicates that adiposity is associated with greater incidence of head and neck cancer (HNC). However, most studies have used self-reported anthropometry which is prone to error.METHODS: Among 363 094 participants in the European Prospective Investigation into Cancer and Nutrition study (EPIC) with measured anthropometry, there were 837 incident cas

International bi-lateral agreements to support the conservation of rainforests to reduce greenhouse gas emissions are growing in prevalence. In 2009, the governments of Guyana and Norway established Guyana’s Low Carbon Development Strategy (LCDS). We examine the extent to which the participation and inclusion of Guyana’s indigenous population within the LCDS is being achieved. We conducted a sing

Only in Sweden, single-family houses account for approximately 30% of energy use in all buildings and a large part uses only electricity for heating. The potential for improvements on energy efficiency in these houses is large. This study theoretically investigates retrofitting of electrically heated Swedish single-family houses by using an air-source heat pump for both space heating and domestic

Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. At an early stage of the disease, AF may terminate spontaneously and is then referred to as paroxysmal AF. On the other hand, when external intervention is required for the arrhythmia to terminate, it is referred to as persistent AF. In this work, a method to discriminate between paroxysmal and persistent AF in the long-t

A number of bioactive natural products have by chromatographic techniques been isolated from extracts of various fungi, and their structures have been determined by spectroscopic and chemical methods. In the screening of fungal extracts for the inhibition of the binding of various ligands to CNS receptors in rat striatal membrane preparations in vitro, bioassay-guided fractionation of extracts of

Elasticity is the ability of a cloud infrastructure to dynamically change the amount of resources allocated to a running service as load changes. We build an autonomous elasticity controller that changes the number of virtual machines allocated to a service based on both monitored load changes and predictions of future load. The cloud infrastructure is modeled as a G=G=N queue. This model is used

Background: HIV-1 infection is associated with an increased incidence of and mortality from tuberculosis. Few community studies have examined the effect of HIV-2 on tuberculosis. Methods: We investigated the association between HIV-1, HIV-2 and active tuberculosis in four districts (population 42 709) in Bissau, capital of Guinea-Bissau, with the highest known seroprevalence of HIV-2 infection in

Low-glycemic index (GI) foods and foods rich in whole grain are associated with reduced risk of type 2 diabetes and cardiovascular disease. We studied the effect of cereal-based bread evening meals (50 g available starch), varying in GI and content of indigestible carbohydrates, on glucose tolerance and related variables after a subsequent standardized breakfast in healthy subjects (n = 15). At br

Sleep apnea is increasing in prevalence, and is an important cause of cardiometabolic diseases and mortality worldwide. Its only established modifiable risk factor is obesity; however, up to half of all sleep apnea cases may occur in non-obese persons, and hence there is a pressing need to identify other modifiable risk factors to facilitate more effective prevention. We sought to examine, for the

Every aspect of modern life is dominated by decision-making and the availability of data. We constantly access, process and evaluate data as we navigate complex and uncertain problem spaces. Communication and Information Technologies (ICTs) have developed to a point where it is possible for very large data sets, measured in Exabyte, to be stored across many servers and gathered by many different p

Advancement of the CALIFA calorimeter project has reached a new milestone with the construction of the first modules of the CALIFA Demonstrator, ultimately to be integrated into the final calorimeter. Aspects and methods of detector optimisation will be discussed, along with characterisation using proton beams of 70

Background: Currently, the implementation of dosimetry in molecular radiotherapy (MRT) is not well investigated, and in view of the Council Directive (2013/59/Euratom), there is a need to understand the current availability of dosimetry-based MRT in clinical practice and research studies. The aim of this study was to assess the current practice of MRT and dosimetry across European countries. Metho