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Progression of frailty and prevalence of osteoporosis in a community cohort of older women—a 10-year longitudinal study

Summary: In community dwelling, 75-year-old women followed 10 years, a frailty index was created at each of three visits. Frailty score increased by ~ 6–7% annually. A higher frailty score was equivalent to being 5–10 years chronologically older. Frailty was associated with low bone density and higher risk of dying. Introduction: To understand the distribution of frailty among a population-based s

The Fc gamma receptor IIa R131H polymorphism is associated with inhibitor development in severe hemophilia A

Background: The development of factor (F) VIII neutralizing alloantibodies (inhibitors) is a major complication of treatment with FVIII concentrates in hemophilia A and the etiology is still poorly understood. The low-affinity Fc gamma receptors (Fc gamma R), which are expressed on immune cells, provide an important link between cellular and humoral immunity by interacting with IgG subtypes. Genet

Kurser i ekonomisk historia

KURSUTBUD VID EKONOMISK-HISTORISKA INSTITUTIONEN Vi erbjuder ett stort antal kurser inom vårt ämnesområde som ger oumbärliga och breda kunskaper om ekonomi, samhälle och historia, men som även underlättar förståelsen av många andra ämnen, t ex nationalekonomi, sociologi, statsvetenskap. När du börjar studera på universitetet läser du kurser på grundnivå. Kurser på grundnivå kan finnas i två nivåer

https://www.ehl.lu.se/organisation/ekonomisk-historiska-institutionen/studera-ekonomisk-historia/kurser-i-ekonomisk-historia - 2026-06-11

Eighteen-year follow-up of the Göteborg Randomized Population-based Prostate Cancer Screening Trial : effect of sociodemographic variables on participation, prostate cancer incidence and mortality

Objective: This study examined whether previously reported results, indicating that prostate-specific antigen (PSA) screening can reduce prostate cancer (PC) mortality regardless of sociodemographic inequality, could be corroborated in an 18 year follow-up. Materials and methods: In 1994, 20,000 men aged 50–64 years were randomized from the Göteborg population register to PSA screening or control

Recurrent Streptococcal Pharyngotonsillitis Studies on etiology and treatment

Popular Abstract in Swedish Akut faryngotonsillit orsakas till ca 40 % av betahaemolytiska grupp A streptokocker (GAS) och till ca 10% av andra bakterier. Ca 30% av fallen är virusutlösta och i ca 20% är genesen okänd. GAS är mycket virulenta humanpatogener som förutom svalg- och hudinfektioner även kan förorsaka livshotande tillstånd som ?streptococcal toxic shock syndrome? och nekrotiserande fasIn acute pharyngotonsillitis group A streptococci (GAS) is the etiological agent in 30-50% of cases. Phenoxymethylpenicillin (pcV) is the drug of choice in Sweden. However, the failure rate is as high as 5-25% and further pcV treatment is followed by still higher failure rates. The background of failures remains largely elusive. The aim of the studies was: 1 To investigate the short- and long-term

Prostate cancer risk assessment in men with an initial P.S.A. below 3 ng/mL : results from the Göteborg randomized population-based prostate cancer screening trial

Abstract Objective: To evaluate the long-term outcome of men with an initial prostate-specific antigen (PSA) level below 3 ng/mL and whether the free-to-total (F/T PSA) ratio is a useful prognostic marker in this range. Materials and methods: This study is based on 5,174 men aged 50–66 years, who in 1995–1996 participated in the first round of the Göteborg randomized screening trial (initial T-PSA

Risks of alcohol and drug use disorders in prostate cancer survivors : a national cohort study

Background: Prostate cancer (PC) survivors may potentially use substances to cope with psychological distress or poorly controlled physical symptoms. Little is known, however, about the long-term risks of alcohol use disorder (AUD) or drug use disorders in men with PC. Methods: A national cohort study was conducted in Sweden of 180-189 men diagnosed with PC between 1998 and 2017 and 1 801 890 age-

IdeS, a secreted proteinase of Streptococcus pyogenes, is bound to a nuclease at the bacterial surface where it inactivates opsonizing IgG antibodies

The important bacterial pathogen Streptococcus pyogenes secretes IdeS (immunoglobulin G-degrading enzyme of S. pyogenes), a proteinase that cleaves human immunoglobulin G (IgG) antibodies in the hinge region resulting in Fc (fragment crystallizable) and F(ab')2 (fragment antigen-binding) fragments and protects the bacteria against phagocytic killing. Experiments with radiolabeled IdeS and flow cyt

Marju Orho-Melander: Gener och diet i samspel – Vetenskap och Hälsa

Marju Orho-Melander: Gener och diet i samspel – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Marju Orho-Melander: Gener och diet i samspel 2011-03-17 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Genetiska faktorer har stor betydelse f

https://www.vetenskaphalsa.se/marju-orho-melander-gener-och-diet-i-samspel/ - 2026-06-11

Quality-policy-for-lund-university

Lägg till titel Page 1 of 1 REGULATORY DOCUMENT COVER PAGE Quality Policy for Lund University Type of regulatory document: Policy Definition of the type of regulatory document: Policies express the management’s overall intended direction or values that are to be taken into account within the area covered by the policy, set frameworks for a specific course of action and constitute a strong recommen

https://www.staff.lu.se/sites/staff.lu.se/files/2025-02/quality-policy-for-lund-university.pdf - 2026-06-12

Postantibiotiska framtider en

Post-Antibiotic Futures – Interrogating the realities and imaginings of the post-antibiotic era THEME 2019-2020 Today, antibiotic resistance is an international fact; an estimated 50,000 people die every year in Europe and The United States as a result of bacteria that have become resistant. However, imagination can easily conjure up an escalation and an even more dystopian future. Thus, it is est

https://www.pi.lu.se/en/sites/pi.lu.se.en/files/2021-01/postantibiotiska_framtider_en.pdf - 2026-06-12

Best Care for the Dying Person 2026

17 November 2026 09:00 to 18 November 2026 17:00 | Conference Welcome to Lund, Sweden, for the 11th Annual Conference of the International Collaborative for Best Care for the Dying Person, 17–18 November 2026. This two‑day event is hosted by the Institute for Palliative Care at Lund University and Region Skåne, and brings together professionals from around the world who are dedicated to improving

https://www.intramed.lu.se/en/calendar/best-care-dying-person-2026 - 2026-06-11

Healthy lifestyle and the risk of pancreatic cancer in the EPIC study

Pancreatic cancer (PC) is a highly fatal cancer with currently limited opportunities for early detection and effective treatment. Modifiable factors may offer pathways for primary prevention. In this study, the association between the Healthy Lifestyle Index (HLI) and PC risk was examined. Within the European Prospective Investigation into Cancer and Nutrition cohort, 1113 incident PC (57% women)

Kp smmv25 eng vt20

Kursguide - Course Syllabus • • • • Details of approval The syllabus was approved by the board of the Department of Service Management and Service Studies on 2019-09-26 to be valid from 2020-01-01, spring semester 2020. General Information The course is included in the Master's (120 credits) programme in Service Management and is the second specialisation-specific course in the Supply Chain Manage

https://www.ses.lu.se/en/sites/ses.lu.se.en/files/kp_smmv25_eng_vt20.pdf - 2026-06-12

$(\epsilon,\delta)$-Freudenthal Kantor triple systems, $\delta$-structurable algebras and Lie superalgebras

In this paper we discuss $(\epsilon,\delta)$-Freudenthal Kantor triple systems with certain structure on the subspace $L_{-2}$ of the corresponding standard embedding five graded Lie (super)algebra $L(\epsilon,\delta):=L_{-2}\oplus L_{-1}\oplus L_0\oplus L_1\oplus L_2; [L_i,L_j]\subseteq L_{i+j}$. We recall Lie and Jordan structures associated with $(\epsilon,\delta)$-Freudenthal Kantor triple sys

Preclinical evaluation of (111)In-DTPA-INCA-X anti-Ku70/Ku80 monoclonal antibody in prostate cancer.

The aim of this investigation was to assess the Ku70/Ku80 complex as a potential target for antibody imaging of prostate cancer. We evaluated the in vivo and ex vivo tumor targeting and biodistribution of the (111)In-labeled human internalizing antibody, INCA-X ((111)In-DTPA-INCA-X antibody), in NMRI-nude mice bearing human PC-3, PC-3M-Lu2 or DU145 xenografts. DTPA-conjugated, non-labeled antibody

Workshops

Sammanfattningar och resultat från workshops Missade du en workshop? Oroa dig inte, vi har sammanfattat resultaten från alla workshops och det presenterade materialet nedan.  Workshops 2023 2 Februari: Att skriva policyinstruktioner - varför, när och hur? Tema: Policy och internationell forskningsutveckling  Workshops 2022 3 Mars: Modellering till stöd för FN:s globala mål om hållbar utveckling Te

https://www.hallbarhet.lu.se/forskare/workshopserie-om-fns-globala-mal/workshops - 2026-06-11

Pausit – the pause program 

Pausit is a pause program that all employees can download to their computer. Pausit offers pause exercises during the working day. It is a computer-based tool which presents exercises that prevent stiffness and pain in the back, shoulders, head and neck. The exercises also reduce stress and improve blood circulation. You choose how often and how long you want to exercise and your own way of doing

https://www.staff.lu.se/employment/work-environment-and-health/health-and-wellness/pausit-pause-program - 2026-06-12

Randomized Trial of a Palliative Care Intervention to Improve End-of-Life Care Discussions in Patients With Metastatic Breast Cancer

Background: Studies show that early, integrated palliative care (PC) improves quality of life (QoL) and end-of-life (EoL) care for patients with poor-prognosis cancers. However, the optimal strategy for delivering PC for those with advanced cancers who have longer disease trajectories, such as metastatic breast cancer (MBC), remains unknown. We tested the effect of a PC intervention on the documen

Towards alkali-stable polymers and hydroxide exchange membranes functionalized with alicyclic quaternary ammonium cations

In the current work, cationic polymers functionalized with N-alicyclic quaternary ammonium (QA) cations were synthesized and characterized as potential hydroxide exchange membranes (HEMs) for application in fuel cells. Three different polymers, namely poly(arylene ether sulfone), spiro-ionene and poly(arylene alkylene), were explored as polymer backbones for the HEMs. Various mono- and spirocyclic