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Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly

9b06302f8ec44cb4f5af312853113fb039fc7797 MOBA03 2025 kursanalys

Untitled Sida 1 av 4 Biologiska institutionen Grund- och avancerad utbildning KURSANALYS Datum 2025-06-02 Kursansvarig: Allan Rasmusson Antal studenter: 24 (exkl. omreg.) Antal svar: 19 Omdöme: 3.8/5 Kursanalys: Molekylärbiologi, MOBA03, VT2025 Sammanställd av Allan Rasmusson i samråd med Urban Johanson Sammanfattning av kursvärderingen Mittkursvärdering: Enligt ombuden har kursens första del fung

https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/9b06302f8ec44cb4f5af312853113fb039fc7797_MOBA03_2025_kursanalys.pdf - 2026-07-12

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OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>