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Clinical studies of extended-half-life recombinant FVIII products for prophylaxis in adults and children : A critical review from the physician's perspective

This review compares the methodology of published clinical studies investigating the extended-half-life (EHL) factor VIII (FVIII) products, rFVIIIFc (efmoroctocog alfa, Elocta®/Eloctate®), BAY 94-9027 (damoctocog alfa pegol, Jivi®), BAX 855 (rurioctocog alfa pegol, Adynovate®) and N8-GP (turoctocog alfa pegol, Esperoct®) including the phase 2/3 studies, A-LONG (NCT01181128), PROTECT VIII (NCT01580

Alveolar mast cells shift to an FcεRI-expressing phenotype in mild atopic asthma: a novel feature in allergic asthma pathology.

Background: A unique feature of alveolar mast cells is their low high-affinity IgE receptor (FcεRI) expression. Recent discoveries in uncontrolled asthma suggest that the appearance of FcεRI-expressing alveolar mast cells may be a novel disease-specific feature of allergic asthma. This study investigates whether increased FcεRI-expressing alveolar mast cells are present in patients with mild aller

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Studieplan 1 | 2026–2027 Studieplan 1 ska fyllas i för varje sökt universitet och termin i detta dokument, och laddas upp i din ansökan om utbyte. En godkänd Studieplan 1 ligger till grund för en eventuell nominering och bedöms av Internationella avdelningen LTH. Instruktioner Personuppgifter · Fyll i dina personuppgifter och bekräfta att du har läst informationen som nämns Värduniversitet Fyll i:

https://www.student.lth.se/fileadmin/lth/utbildning/studerautomlands/andra_filer/LTH_Studieplan_2026-2027.docx - 2026-05-28

Studies on hereditary C2 deficiency: Frequent occurrence of severe infections, atherosclerosis and rheumatological manifestations

Popular Abstract in Swedish Komplementsystemet utgör en del av den medfödda immuniteten och är viktigt i försvaret mot angripande mikroorganismer. Ärftlig C2-brist (C2D) är en av de vanligaste bristerna inom komplementsystemet och förekommer i en frekvens av 1: 20 000 hos personer med västerländsk härstamning. I de aktuella undersökningarna har mer än 40 personer med C2D identifierats och observerThe complement system is a part of the innate immunity and is essential in the defence against microorganisms. Hereditary C2 deficiency (C2D) is one of the most common complement deficiency states with an estimated prevalence of 1:20,000 in persons of Western descent. In the present investigation, the identification of more than 40 C2D persons at a single centre combined with long observation peri

Cfewp35

CFE_WP_35 Final 1 CFE Working paper series No. 35 Discursive Elements in the (de)Banalisation of Nationalism. A Study of Speeches by Gordon Brown and Nicolas Sarkozy1. Pascal Yan Sayegh Pascal Yan Sayegh IETT, Université de Lyon (Jean Moulin). yansayegh@iett.eu CFE Working papers are available at the website of the Centre for European Studies www.cfe.lu.se 2 CFE Working paper series No. 35 Pascal

https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2020-12/cfewp35.pdf - 2026-05-29

Brutal Need : Lawyers and the Welfare Rights Movement, 1960-1973 - The Raoul Wallenberg Institute of

Brutal Need : Lawyers and the Welfare Rights Movement, 1960-1973 - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysi

https://rwi.lu.se/publications/brutal-need-lawyers-and-the-welfare-rights-movement-1960-1973/ - 2026-05-28

“The Politics of Sexual Health in Vietnam” - The Raoul Wallenberg Institute of Human Rights and Huma

“The Politics of Sexual Health in Vietnam” - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation

https://rwi.lu.se/publications/the-politics-of-sexual-health-in-vietnam/ - 2026-05-29

Targeting tumour vasculature by inhibiting activin receptor-like kinase (ALK)1 function

Angiogenesis is a hallmark of cancer and is now a validated therapeutic target in the clinical setting. Despite the initial success, anti-angiogenic compounds impinging on the vascular endothelial growth factor (VEGF) pathway display limited survival benefits in patients and resistance often develops due to activation of alternative pathways. Thus, finding and validating new targets is highly warr

Affinity fractionation of lymphocytes using a monolithic cryogel.

A new type of continuous, supermacroporous, monolithic, cryogel affinity adsorbent was developed, allowing specific fractionation and separation of human peripheral blood lymphocytes in a chromatographic format. The affinity adsorbent was used to design a novel cell separation strategy, which was based on the interaction of protein A from Staphylococcus aureus with cells bearing IgG antibodies on

Comparing Chemical Reaction Mechanisms for Jet Fuel in Turbulent Premixed Combustion Simulations

The compositions of alternative jet fuels can vary radically, and the consequences of these differences are a subject of ongoing investigation. Numerical combustion simulations are vital to this research and require chemical reaction mechanisms that efficiently and accurately capture the chemical pathways of combustion. Here, we present the recently developed Z79 collection of small pathway-centri

The Comparative and Combined Effects of Nitric Oxide and Higher Alkanes in Sensitizing Methane Oxidation

The comparative and combined effects of nitric oxide (NO) and higher alkanes on methane oxidation were examined by experimentation and kinetic modeling. Experiments were conducted using fuel-lean, lower-alkanes mixtures with NO (0-400 ppm v/v) in an atmospheric flow reactor at residence time of 2 s over the temperature range of 820-950 K. NO was found to greatly promote methane conversion, and its

Experimental and numerical study of ground vortex interaction in an air-intake

The airflow field around air-intake related geometries has been investigated experimentally and numerically. The configuration of the experimental set-up is used to model a jet engine running near the ground. The experiments have been carried out using both PIV and LDA techniques in order to obtain the mean and fluctuating velocity field as well as the low speed frequencies related to the system o

Utvärdering av markfunktion vid användning av bergkross som återfyllnadsmassa

A commonly used method in remediation projects is to excavate the contaminated soil and treat it in another location or put it in a landfill. The remediation site is then refilled with crushed stones. When the original soil and its initial organisms are removed and replaced with only crushed stones, the environmental properties are changed. This can affect both primary production and the flora and