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Ribonucleotide reductases (RNRs) catalyze the reduction of ribonucleotides to deoxyribonucleotides, the building blocks for DNA synthesis, and are found in all but a few organisms. RNRs use radical chemistry to catalyze the reduction reaction. Despite RNR having evolved several mechanisms for generation of different kinds of essential radicals across a large evolutionary time frame, this initial r
Uncharacterized side activities of enzymes can have significant negative effects on reaction products and yields. Hence, their identification and characterization is crucial for the development of successful reaction systems. Here, we report the presence of feruloyl esterase activity in CtXyn5A from Acetivibrio thermocellus besides its well-known arabinoxylanase activity for the first time. Both r
Uncharacterized side activities of enzymes can have significant effects on reaction products and yields. Hence, their identification and characterization are crucial for the development of successful reaction systems. Here, we report the presence of feruloyl esterase activity in CtXyn5A from Acetivibrio thermocellus, besides its well-known arabinoxylanase activity, for the first time. Activity ana
Pyridoxal 5′-phosphate (PLP), the biologically active form of vitamin B6, is an essential cofactor in many biosynthetic pathways. The emergence of PLP-dependent enzymes as drug targets and biocatalysts, such as tryptophan synthase (TS), has underlined the demand to understand PLP-dependent catalysis and reaction specificity. The ability of neutron diffraction to resolve the positions of hydrogen a
We present a solution for long-term direct current resistivity and time-domain induced polarization (DCIP) monitoring, which consists of a monitoring system and the associated software that automates the data collection and processing. This paper describes the acquisition system that is used for remote data collection and then introduces the routines that have been developed for pre-processing of
This paper considers the effects of defects in the form of cracks on the failure properties in the thickness direction of multilayered board. The objective was to study how the peak stress value changes with various crack lengths under various load conditions. Specimens with manufactured cracks cut parallel to the machine-direction–cross-machine-direction plane were glued in the Arcan device and t
C4b-binding protein (C4BP) is a plasma glycoprotein involved in regulation of the complement system. C4BP consists of seven alpha-chains and one unique beta-chain, all constructed of repeating complement control protein (CCP) modules. The beta-chain, made up of three CCPs, binds tightly to vitamin K-dependent protein S, a cofactor to anticoagulant activated protein C. When bound to C4BP, protein S
In recent years, particularly following the definition of the UN Sustainable Development Goals (SDGs) for 2030, Nature-Based Solutions (NBS) have gained considerable attention, capturing the interest of both the scientific community and policymakers committed to addressing urban environmental issues. However, the need for studies to guide decision-makers in identifying suitable locations for NBS i
Unhealthful lifestyles underpin much of the burden of cardiometabolic disease affecting contemporary societies. Our overarching objective is to discover and optimise measurable biomarkers that can be used to stratify patient populations into subgroups that can be treated more effectively with targeted lifestyle therapies, at lesser cost and with fewer adverse events than conventional approaches
Mademoiselle Anna et sa petite copine Stephanie ont décidé qu'elles vont aller en Italie, cette été. Cette soirée là elles sont chez Anna et elles boivent du café et parlent beacoup de ce voyage qui se rendre. Ni Anna ni stéphanie a été en Italie, mais elles croyent qu'elles savent qui va se passer y. Elles vont manger beaucoup de pasta, vont rencontrer des graçons Italien et elle vont etre plusie
https://projekt.ht.lu.se/fileadmin/user_upload/project/cefle/textes/le_sous-corpus_transversal/stade_d/Disa.txt - 2026-07-06
LEVIC är en tvärvetenskaplig forskargrupp med forskare från juridik, filosofi, kognitiv psykologi och matematisk statistik. Vår forskning handlar om bevisvärdering, framförallt bevisvärdering i brottmål. Vi undersöker empiriskt hur bevisvärdering görs i domstolarna, och vi är särskilt intresserade av kognitiv bias, t.ex. olika typer av matematiska tankefel i de sannolikhetsbedömningar som uppkommeLEVIC is a cross-disciplinary research group with researchers from law, philosophy, cognitive psychology and statistics. Our research concerns legal fact-finding, especially criminal evidence. We investigate empirically how legal decision-makers (judges or jurors) evaluate evidence, and we are particularly interested in cognitive bias and probabilistic fallacies. We do research that aims to improv
Deux copines, Marie et Camille preparent un voyage en Italie. Marie est une fille grosse et courte avec des cheveux blonds et Camille est la contraire, avec des cheveux bruns et elle est haute. Marie rêve d'être à la plage. Camille rêve de des garcons Italiens. Quand elles counduirent, elles noticent la voiture verte est trop petite. C'est ne pas place pour ses valises. Elles sont désolées. Mais e
https://projekt.ht.lu.se/fileadmin/user_upload/project/cefle/textes/le_sous-corpus_transversal/stade_c/Carole.txt - 2026-07-06
Aim: It has been claimed that supraspinal structures are necessary forthe depression of nocifensive behaviour elicited by acupuncture or acupuncturelike (AL) stimulation. However, nocifensive reflexes in the spinal catwere inhibited for long periods by a mechanism releasing opieids on AL conditioning stimulation of groups II-III muscle afferents (Sj~lund and Eriksson, Neurosci.Lett. S3:264:1979).
The multi-layer dynamic model SAFE was applied to the forested catchment istebna (Southern Poland), to study recovery from acidification. Environmental pollution in the area has been historically high. The model uses data from an intensive monitoring plot established in 1999 in a spruce stand, which was planted in 1880. Observations showed that the soil was depleted of base cations. The measured b
Omkring 600 barn och tonåringar arbetar på Managuas stora soptipp, denbstörsta i Nicaragua. De samlar och sorterar avfall på den öppna tippen, sombtäcker ett 7 km2 stort område i stadens utkant vid stranden av Managuasjön. Sådant arbete, som förekommer i många stora städer i utvecklingsländer, ansesbvara ett av de mest riskfyllda typerna av barnarbete som finns. Ändå är kunskapen om sådant arbete About 600 children and teenagers work at Managua's landfill, the largest in Nicaragua. They collect and sort waste at the open dump, which covers an area of 7 km2 on the outskirts of the city on the shores of Lake Managua. Such work, which occurs in many large cities in developing countries, is considered to be one of the riskiest types of child labor that exists. Nevertheless, knowledge of such w
The emergence of digital technology has led researchers, businesses, and entrepreneurs to reflect more on the potential value that Augmented Reality (AR) can play in tourism. Although the relationship between authenticity and travel intention has been examined previously, little is known about how authenticity influences tourist travel intention after an AR experience. To fill this research gap, t
The catalytic oxidation of HCl by molecular oxygen (Deacon process) over ceria allows the recovery of molecular chlorine from the omnipresent HCl waste produced in various industrial processes. In previous density functional theory (DFT) model-calculations by Amrute et al. [ J. Catal. 2012, 286, 287−297.], it was proposed that the most critical reaction step in this process is the displacement of
