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The use of asymmetric time constraints in 4-D ERT inversion

Time-lapse resistivity surveys are commonly used to monitor temporal changes in the subsurface. In certain cases, it is known from other information that the resistivity will only decrease or increase with time. The 4-D resistivity smoothness-constrained inversion method reduces artifacts due to noise by including a temporal roughness filter constraint that ensures the temporal changes vary in a s

Assessing taxonomic and functional change in British breeding bird assemblages over time

Aim: The aim was to identify the primary drivers of compositional change in breeding bird assemblages over a 40-year period. Location: Britain. Time period: From 1970 to 2010. Major taxa studied: Birds. Methods: Using morphological trait measurements and a dataset of presence–absence data for British breeding birds surveyed in 10 km × 10 km hectads during two time periods, we calculated temporal t

Prevalence and factors associated with faecal carriage of extended-spectrum β-lactamase-producing Enterobacterales among peripartum women in the community in Cambodia

BACKGROUND: In Southeast-Asia, where many conditions associated with dissemination of ESBL-producing Enterobacterales (ESBL-E) in the community are met, data from the community are scarce but show high ESBL-E carriage prevalence. Maternal ESBL-E colonization is considered a risk factor for neonatal colonization, which is the first step towards developing neonatal sepsis. Despite this, ESBL-E carri

Ophiostomatoid fungi synergize attraction of the Eurasian spruce bark beetle, Ips typographus to its aggregation pheromone in field traps

Eurasian spruce bark beetle, Ips typographus is a destructive pest of the Norway spruce (Picea abies). Recent outbreaks in Europe have been attributed to global warming and other anthropogenic impacts. Bark beetles are guided by multiple complex olfactory cues throughout their life cycle. Male-produced aggregation pheromones, comprising 2-methyl-3-buten-2-ol and cis-verbenol, have been identified

Secondary aerosol formation in marine Arctic environments : a model measurement comparison at Ny-Ålesund

In this study, we modeled the aerosol particle formation along air mass trajectories arriving at the remote Arctic research stations Gruvebadet (67 m a.s.l.) and Zeppelin (474 m a.s.l.), Ny-Ålesund, during May 2018. The aim of this study was to improve our understanding of processes governing secondary aerosol formation in remote Arctic marine environments. We run the Lagrangian chemistry transpor

The Integrated Use of Dendrochronological Data and Paleoecological Records From Northwest European Peatlands and Lakes for Understanding Long-Term Ecological and Climatic Changes—A Review

Our overall understanding of long-term climate dynamics is largely based on proxy data generated from archives such as ice cores, ocean sediments, tree rings, speleothems, and corals, whereas reconstructions of long-term changes in vegetation and associated climate during the Holocene are largely based on paleoecological records from peat and lake sequences, primarily pollen and plant macrofossil

Drought recorded by Ba/Ca in coastal benthic foraminifera

Increasing occurrences of extreme weather events, such as the 2018 drought over northern Europe, are a concerning issue under global climate change. High-resolution archives of natural hydroclimate proxies, such as rapidly accumulating sediments containing biogenic carbonates, offer the potential to investigate the frequency and mechanisms of such events in the past. Droughts alter the barium (Ba)

Cancer incidence in a male adult population in relation to estimated protracted colon dose – A nested case control study in Northern Sweden after the Chernobyl Nuclear Power Plant accident

Introduction: Uncertainty in the dose-response of low dose radiation raised concern of an increased cancer incidence in Sweden after the Chernobyl Nuclear Power Plant (NPP) accident. Material and methods: A closed cohort was created of all males ≥18 years of age living in the Northern Sweden in 1986. In total 826,400 individuals were enrolled including 40,874 hunters. A nested case-control design

Miljö och konkurs - miljöansvar när verksamhetsutövaren går i konkurs

Uppsatsen behandlar hur miljörelaterade fordringar hanteras när en verksamhet går i konkurs och i vilken utsträckning principen om att förorenaren ska betala får genomslag i svensk konkursrätt. Utgångspunkten är de praktiska problem som uppstår när kostsamma efterbehandlingsåtgärder aktualiseras först efter konkursutbrottet, samtidigt som det inte finns någon generell skyldighet för staten eller kThis thesis examines how environmental claims are treated when a business is declared bankrupt, and to what extent the polluter pays principle is upheld in Swedish bankruptcy law. The point of departure is the practical difficulties that occur when costly remediation measures become relevant only after the opening of bankruptcy proceedings, while there is no general legal obligation for the State

Plasma Protein Profile Associated With a Family History of Early-Onset Coronary Heart Disease

BACKGROUND: – Proteins linked to heritable coronary heart disease (CHD) could uncover new pathophysiological mechanisms of atherosclerosis. We report on the protein profile associated with a family history of early-onset CHD and whether the relation between proteins and coronary atherosclerotic burden differs according to family history status, as well as inferences from Mendelian randomization. M

Effect of a continuous trauma quality improvement programme on mortality in urban India: a non-randomised controlled trial

Background Trauma is the leading cause of quality-related mortality in low- and middle-income countries, with an estimated two million preventable deaths each year. Although trauma quality improvement programmes have been utilised in high-income countries for more than three decades, there is no high-level evidence of their effect on patient outcomes. We aimed to assess whether implementing a cont

Service continuity in Swedish grocery distribution under disruptions - Evaluating microbuffers across disruption scenarios

Sweden’s grocery distribution is routed through a limited number of upstream hubs and relies on corridors and ferry links. When disruptions affect a hub or a critical link, reallocations propagate fast and travel times increase, with some areas losing coverage temporarily. Decentralising the whole system is costly, so targeted resilience options must be evaluated. The purpose of this thesis is to

Knowing Nuclear Weapons Tests : Witness Activism and Oppositional Knowledge in the Cold War Colonial Pacific

Denna avhandling undersöker hur aktörer i Stilla havet producerade och spred oppositionell kunskap om kärnvapentester från 1950-talet till början av 2000-talet, med Franska Polynesien i fokus. För att analysera detta lanseras begreppet vittnesaktivism som övergripande står för organiserade praktiker av vittnesmål, dokumentinsamling, arkivering och transnationell spridning, genom vilka aktörer utmaThis dissertation examines how actors in the Pacific produced, mobilized, and circulated oppositional knowledge about nuclear weapons testing from the 1950s to the early 2000s, with French Polynesia as its primary focus. At its core is witness activism: coordinated practices of testimony, document retrieval and annotation, archiving, publication, and transnational circulation through which activis

Zoledronic Acid Add-on Therapy for Standard-Risk Ewing Sarcoma Patients in the Ewing 2008R1 Trial

PURPOSE: The phase III, open-label, prospective, multicenter, randomized Ewing 2008R1 trial (EudraCT2008-003658-13) was conducted in 12 countries to evaluate the effect of zoledronic acid (ZOL) maintenance therapy compared with no add-on regarding event-free survival (EFS, primary endpoint) and overall survival (OS) in standard-risk Ewing sarcoma (EWS). PATIENTS AND METHODS: Eligible patients had

The challenge of comparing pollen-based quantitative vegetation reconstructions with outputs from vegetation models - a European perspective

We compare Holocene tree cover changes in Europe derived from a transient Earth system model simulation (Max Planck Institute Earth System Model - MPI-ESM1.2, including the land surface and dynamic vegetation model JSBACH) with high-spatial-resolution time slice simulations performed in the dynamic vegetation model LPJ-GUESS (Lund-Potsdam-Jena General Ecosystem Simulator) and pollen-based quantita

D4.2: Risk Assessment for Wetland Sediment Applications on Agricultural Land : WP4 Nutrient Recovery from Streams

This deliverable reports on Risk Assessment for Wetland Sediment Applications on Agricultural Land. The main content is a thorough and critical evaluation (literature review) of the wetland coupled agriculture and the related concerns such as nutrients, sediments and contamination risks. This will also be supported by the two case studies. Constructed wetlands act as traps for substances carried w

Elevated Galectin-3 levels in the tumor microenvironment of ovarian cancer – implication of ROS mediated suppression of NK cell antitumor response via tumor-associated neutrophils

Introduction: Ovarian cancer is a lethal disease with low survival rates for women diagnosed in advanced stages. Current cancer immunotherapies are not efficient in ovarian cancer, and there is therefore a significant need for novel treatment options. The β-galactoside-binding lectin, Galectin-3, is involved in different immune processes and has been associated with poor outcome in various cancer

Three Decades of Changing Nutrient Stoichiometry from Source to Sea on the Swedish West Coast

European ecosystems have been subject to extensive shifts in anthropogenic disturbance, primarily through atmospheric deposition, climate change, and land management. These changes have altered the macronutrient composition of aquatic systems, with widespread increases in organic carbon (C), and declines in nitrogen (N) and phosphorus (P). Less well known is how these disturbances have affected nu