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Although bottom water hypoxia (O2 −1) is presently widespread in the Baltic Sea coastal zone, there is a lack of insight into past changes in bottom water oxygen in these areas on timescales of millennia, and the possible driving factors. Here, we present a sediment-based environmental reconstruction of surface water productivity, salinity and bottom water oxygen for the past 5400 years at Gåsfjär
Peak bone mass is normally reached in the third decade of life. Previously, in the population-based PEAK-25 cohort (n = 1061, age 25.5 ± 0.2), we demonstrated that bone mineral density in the population-based PEAK-25 cohort is comparatively high; therefore, this study aimed to determine if the calcaneus microarchitecture mirrored this. In the process, we describe normative quantitative ultrasound
Deeper winter snow is hypothesized to favor shrub growth and may partly explain the shrub expansion observed in many parts of the arctic during the last decades, potentially triggering biophysical feedbacks including regional warming and permafrost thawing. We experimentally tested the effects of winter snow depth on shrub growth and ecophysiology by measuring stem length and stem hydrogen (δ2H),
One risk factor for osteoporosis which has attracted increasing attention in recent years is exposure to cadmium. The aim of this study was to examine the associations between low-level cadmium exposure, from diet and smoking, and BMD and incident fractures in elderly men. The study population consisted of 936 men from the Swedish cohort of the MrOS study, aged 70-81 years at inclusion (year 2002-
Background Trauma is the leading cause of quality-related mortality in low- and middle-income countries, with an estimated two million preventable deaths each year. Although trauma quality improvement programmes have been utilised in high-income countries for more than three decades, there is no high-level evidence of their effect on patient outcomes. We aimed to assess whether implementing a cont
Denna avhandling undersöker hur aktörer i Stilla havet producerade och spred oppositionell kunskap om kärnvapentester från 1950-talet till början av 2000-talet, med Franska Polynesien i fokus. För att analysera detta lanseras begreppet vittnesaktivism som övergripande står för organiserade praktiker av vittnesmål, dokumentinsamling, arkivering och transnationell spridning, genom vilka aktörer utmaThis dissertation examines how actors in the Pacific produced, mobilized, and circulated oppositional knowledge about nuclear weapons testing from the 1950s to the early 2000s, with French Polynesia as its primary focus. At its core is witness activism: coordinated practices of testimony, document retrieval and annotation, archiving, publication, and transnational circulation through which activis
PURPOSE: The R2Pulm trial was conducted to evaluate the effect of busulfan-melphalan high-dose chemotherapy with autologous stem-cell rescue (BuMel) without whole-lung irradiation (WLI) on event-free survival (main end point) and overall survival, compared with standard chemotherapy with WLI in Ewing sarcoma (ES) presenting with pulmonary and/or pleural metastases. METHODS: From 2000 to 2015, we e
Accurately quantifying soil base cation pool sizes is essential to interpreting the sustainability of forest harvests from element mass-balance studies. The soil-exchangeable pool is classically viewed as the bank of "available" base cations in the soil, withdrawn upon by plant uptake and leaching and refilled by litter decomposition, atmospheric deposition and mineral weathering. The operational
Despite advances in the treatment quality of HIV throughout the world, several countries are still facing numerous obstacles in delivering HIV treatment at a sufficiently high quality, putting patients' lives in jeopardy. The aim of this status article is to give an overview of HIV treatment outcomes in the West African country, Guinea-Bissau, and to assess how newer treatment strategies such as l
The immune system has evolved through thousands of years and its architecture has challenged the medical field since the first hieroglyphs and will likely continue do so. With our co-evolution with millions of other species, the complexity to treat infectious diseases has been a race in increasing speed ever since. The establishment of penicillin shortened the length of that battle against a broad
PURPOSE: The prevalence of iron deficiency (ID) in Left Ventricular Assist Device (LVADs) recipients is not known nor has the association between ID and peak oxygen uptake (VO2) been reported. The aim of this study was to study to investigate the prevalence of ID in this population and the association between ID and VO2. METHODS: Data was included from LVAD recipients at Rigshospitalet, Denmark (D
This deliverable reports on Risk Assessment for Wetland Sediment Applications on Agricultural Land. The main content is a thorough and critical evaluation (literature review) of the wetland coupled agriculture and the related concerns such as nutrients, sediments and contamination risks. This will also be supported by the two case studies. Constructed wetlands act as traps for substances carried w
Introduction: Ovarian cancer is a lethal disease with low survival rates for women diagnosed in advanced stages. Current cancer immunotherapies are not efficient in ovarian cancer, and there is therefore a significant need for novel treatment options. The β-galactoside-binding lectin, Galectin-3, is involved in different immune processes and has been associated with poor outcome in various cancer
Cancer har kommit att bli en av de största folksjukdomarna i den industrialiserade västvärlden och enbart i Sverige insjuknar över 55 000 personer varje år. Det faktum att var tredje person kommer att drabbas av en cancersjukdom någon gång under sin livstid innebär, förutom ett stort mänskligt lidande, att samhället står inför stora folkhälsopolitiska utmaningar att nå medborgarna med sina hälsofr
Objectives: Chronic pain is common in older adults, yet little is known of its development and the factors that predict its persistence and onset at old age. The aims of this longitudinal cohort study were to examine the prevalence and incidence of chronic pain and to explore possible risk factors for its persistence and onset in a representative sample of older Swedish adults. Method: Data were c
Migration patterns of Nordic Greylag Geese Anser anserwere studied by means of neck-collaring. A total of 4173birds (738 breeders, 1999 goslings and 1436 moulters;most moulters subsequently identified as belonging to aspecified breeding population) was marked throughoutNorway, Sweden, Denmark and Finland during 1984–1994. This report is based on observations made up to 30June 1995. In general, Nor
