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Motivated by growing considerations of the scale, severity, and risks associated with human exposure to indoor particulate matter, this work reviewed existing literature to: (i) identify state-of-the-art experimental techniques used for personal exposure assessment; (ii) compare exposure levels reported for domestic/school settings in different countries (excluding exposure to environmental tobacc
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Serglycin is a proteoglycan expressed by some malignant cells. It promotes metastasis and protects some tumor cells from complement system attack. In the present study, we show for the first time the in situ expression of serglycin by breast cancer cells by immunohistochemistry in patients' material. Moreover, we demonstrate high expression and constitutive secretion of serglycin in the aggressive
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Paleomagnetic data, although undeniably limited, have been used to constrain complex time-varying geomagnetic field models. Here we present four different versions of a time varying geocentric dipole model for the past approximately 9000 years based on a limited selection of sedimentary paleomagnetic data with good spatial coverage. The robustness of the modeling approach is evaluated using modern
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Glypicans are cell-surface heparan sulfate proteoglycans that regulate Wnt, Hedgehog, bone morphogenetic protein, and fibroblast growth factor signaling through their heparan sulfate chains. Recent studies have shown that glypican core proteins also have functional roles in growth factor signaling, but biochemical and structural knowledge regarding the core proteins is limited. Glypican-1 is invol
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The generation of diversity for directed protein evolution experiments shows an important bottleneck in the in vitro random mutagenesis protocols. Most Of them are biased towards specific changes that eventually confer a predicted and conservative mutational spectrum, limiting the exploration of the vast protein space. The current work describes a simple methodology to in vivo recombine mutant lib
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Despite numerous challenges, since its independence, Uzbekistan, with the exception of the May 2005 Andijan events, has enjoyed extraordinary political stability and not recorded any considerable cases of interethnic or interfaith conflict, regime change or civil war, whereas neighboring Kyrgyzstan, labeled an “island of democracy” by the Western world, has experienced numerous conflicts and chaos
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Background: Screening for bacterial colonization and antimicrobial resistance (AMR) among a defined population could aid in the identification of at-risk populations and provide targets for antibiotic stewardship and infection control programmes. Methods: Two hundred and sixty-eight participants at 11 Swedish nursing homes underwent serial screening for colonization with Escherichia coli between M
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The productivity of agricultural and forest ecosystems in regions at higher latitudes is to a large extent governed by low temperature and moisture conditions. Environmental conditions are acting both above- and below-ground and regulating carbon fluxes and evapotranspiration. However, the understanding of various feedbacks between vegetation and environmental conditions is still unclear. In this
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We aim to reinforce the importance of more qualitative empirical studies researching the particularities of co-creation efforts, in the context of new, ambiguous mutations of work and organization generated by internet technologies. While answering our research question we will look into personal accounts referring to the individual’s experience of volunteering for Mozilla, and we will contribute
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Examensarbetet fokuserar på utvärdering samt testning av FLEXNET, ett Unattended Ground Sensor (UGS) system utvecklat av Bertin Exensor. FLEXNET:s grund-läggande syfte är att övervaka stora områden utan att kräva omfattande resurser i form av personal som aktivt övervakar och underhåller systemet på plats. Vid utvecklandet av större system kan det ofta vara besvärligt att utföra fullskaliga test
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The trend towards greater globalisation brings the matter of cultural identity to the foreground. Transnational corporations or business networks are culturally diverse places where cultural othering – simply put, the assumption that someone is fundamentally different from you based on the cultural identity projected on- or associated with them – can significantly impact operations across the hier
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Bakgrund: Folkhögskolan är ett unikt nordiskt fenomen med stor möjlighet till anpassning av studierna. Studier i sig påverkar aktivitetsbalansen, vilken är upplevelsen av balans mellan måsten och meningsfulla aktiviteter. Folkhögskolestuderande är en underbeforskad grupp framförallt inom arbetsterapi. För att beskriva komplexiteten i aktivitetsbalans används aktivitetsvetenskapliga modeller. SyfteBackground: Folk high schools are a uniquely Nordic phenomenon with individualized pedagogy. Studying affects occupational balance, which is the experience of balance between tasks and meaningful activities. Folk high school students as a group are not widely researched, particularly in combination with occupational therapy. To describe the complexity of occupational balance, models linked to occu
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This thesis views Sankt Lars begravningsplats (cemetery) as a deathscape where histories of institutionalization, social exclusion, and neoliberal expansion are spatially materialized in the cemetery’s ecology. Tied to the former Sankt Lars asylum on the margins of Lund, Sweden, the cemetery embodies the intersections of human and nonhuman forces where ecological transformations intertwine with cu
