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In this study, a combined workflow of computational methodologies is introduced to explore the transformative landscape of the ancient city of Savatra (Central Anatolia Region, Türkiye), which faces long-term risks stemming from natural and anthropogenic threats. Emphasis was placed on regional and local scale landscape analysis, employing aerial and ground-based remote-sensing techniques to unrav
Infectious and parasitic agents (IPAs) and their associated diseases are major environmental stressors that jeopardize bee health, both alone and in interaction with other stressors. Their impact on pollinator communities can be assessed by studying multiple sentinel bee species. Here, we analysed the field exposure of three sentinel managed bee species (Apis mellifera, Bombus terrestris and Osmia
Following the Paris Agreement's climate targets and the modelling community's scenarios of how to reach them, carbon dioxide removal is gaining increasing importance in national climate policies. This is also the case in Denmark – considered by itself and others a climate frontrunner – where biochar is envisioned to cover 10% of the 2030 reduction goal. However, apart from research experiments and
Several enzymes from the metallo-β-lactamase-like family of lactonases (MLLs) degrade N-acyl L-homoserine lactones (AHLs). They play a role in a microbial communication system known as quorum sensing, which contributes to pathogenicity and biofilm formation. Designing quorum quenching (QQ) enzymes that can interfere with this communication allows them to be used in a range of industrial and biomed
Bacterial arylmalonate decarboxylase (AMDase) and evolved variants have become a valuable tool with which to access both enantiomers of a broad range of chiral arylaliphatic acids with high optical purity. Yet, the molecular principles responsible for the substrate scope, activity, and selectivity of this enzyme are only poorly understood to date, greatly hampering the predictability and design of
Human-induced impacts are increasing pressure on coastal ecosystems, particularly on benthic ecosystems in high-latitude regions. It has become evident that three of the greatest marine environmental challenges related to anthropogenic activity are warming, ocean acidification, and deoxygenation. The effect of these environmental changes on our uncertain future has created a need to understand the
Antibodies and avidity maturation contribute to long-lasting immunity, and previous COVID-19 seems to enhance the immune response after vaccination. The aim of this study was to compare the immune response after vaccination between COVID-19 convalescents and naïve patients. Blood samples from COVID-19 convalescents and naïve patients, taken 1, 3 and 6 months after the second dose of vaccine (mRNA-
tRNA-derived stress-induced RNAs (tiRNAs) are a new class of small non-coding RNA that have emerged as important regulators of cellular stress responses. tiRNAs are derived from specific tRNA cleavage by the stress-induced ribonuclease angiogenin (ANG). Loss-of-function mutations in the ANG gene are linked to amyotrophic lateral sclerosis (ALS), and elevated levels of specific tiRNAs were recently
ABSTRACTObjectivesAn emerging body of research reveals a heightened risk of gambling problems among elite athletes, particularly among males, but these studies often suffer from small sample sizes and lack diverse representation across sports and groups. This study aimed to investigate gambling problems and their correlates among elite male and female ice hockey players in Sweden’s top leagues.Met
The Andes mountains extend north–south in a latitudinal gradient of 8500 km. Because of the great climatic variety and the peculiar north–south orographic distribution, lakes are highly diverse, including different lake origins and contrasting morphometries. We reviewed >700 ecological studies on Andean lakes to identify the main threats to these freshwater systems. The most important threats are
Background: Since its inception in 1980, the MOHL index (% patients who are male, have occupational, hand, or leg dermatitis, respectively) and its later evolutions until the presently used MOAHLFA(P) index (adding % patients with atopic dermatitis, face dermatitis, age 40+ years and positive reaction(s) to ≥ 1 baseline series allergen) have been intended to convey important demographic and clinic
Almost all realms of Chinese society have been affected by privatization. Education is no exception, although its privatization does not necessarily affect the school system per se. Chinese scholars have usually provided two explanations for privatized schooling in China: 'massification' (educational expansion) and 'pluralization' (diversification). In my research project on private schools in ur
Several yeast species, usually engineered by humans in order to produce compounds of biotechnological interests, are currently used as cellular factories. This thesis presents two main themes. In the first, Saccharomyces cerevisiae is used for bio-ethanol production from lignocellulose hydrolysates and in the second Pichia pastoris is used for the heterologous expression of human ameloblastin. Th
Popular Abstract in Swedish I avhandlingsarbetet har spridning av förorenad jord till följd av jordskred till ytvatten studerats genom att sammankoppla faran för miljö och hälsa från förorenad mark med faran för skred. Skredriskbedömningar görs på många håll runt om i världen, likaså riskbedömning av förorenad jord, dock görs dessa helt separerade från varandra och det finns därför väldigt lite inLandslide risk assessments and environmental risk assessments are routinely carried out in many countries exposed to landslide hazards and/or contaminated soil hazards, but separately from each other. By combining results from different types of risk assessments and superimposing the results, possible multi-hazards may be revealed, which is not the case when the results are only displayed independ
Policy intervention schemes for increased deployment of solar photovoltaics (PV) have been launched in several countries, with varying success. In order to ensure an efficient deployment of the technology, thorough knowledge is needed about relevant present actors and institutions, and about how a desirable actor base and institutional setup should look like; mere cost reductions are not enough to
Previous studies have shown that the predominant proteins secreted by the seminal vesicles are transglutaminase substrates which have undergone major structural alterations during evolution. In man, they are known as semenogelin I and II; recently it was shown that, similar to man, several new world and old world monkeys carry two semenogelin genes as well, the exception being the cotton-top tamar
In this paper I draw on two case studies of how environmental impacts are assessed in large scale golf developments to illustrate the political ecology of leisure and how countrysides are reshaped to cater for elite consumption (McCarthy 2008). In 2008 Trump International Golf Links Scotland gained permission to build a golf resort, potentially the largest in the UK, along the Aberdeenshire coast.
Popular Abstract in Swedish Många industridesignkonsultföretag har som ambition att anta en strategisk roll i sina kundföretag. Design ses i detta sammanhang som ett viktigt konkurrensmedel med en kreativ process som stödjer en innovationsdriven verksamhet. Samtidigt saknas ofta kunskap, framförallt i små och medelstora företag - SMF, om hur designmetoder och processer kan bidra utöver skapandet aWhile the design industry is moving into new domains, it seems that potential customers do not always understand how the designer can contribute beyond the aesthetically appealing product. The overall purpose of this thesis is to expand our understanding of design as an enabling service in the context of small and medium sized enterprises. Enabling design services have the potential to result in o
Even though language proficiency in children is strongly related to success in almost all domains, neurocognitive studies of L2 processing are typically limited to adults with several years of exposure, who may use general cognitive mechanisms to compensate for any difficulties in L2 processing. For example, whereas previous studies of adult bilinguals have reported differences in the anterior neg
There is a growing need for selective recognition of microorganisms in complex samples due to the rapidly emerging importance of detecting them in various matrices. Most of the conventional methods used to identify microorganisms are time-consuming, laborious and expensive. In recent years, many efforts have been put forth to develop alternative methods for the detection of microorganisms. These m
