Filetype
Chemokines comprise a class of structurally related proteins that are involved in many aspects of leukocyte migration under basal and inflammatory conditions. In addition to the large number of genes, limited processing of these proteins by a variety of enzymes enhances the complexity of the total spectrum of chemokine variants. We have recently shown that the native chemokine CXCL10 is processed
Saturated pool boiling heat transfer is investigated experimentally on a copper substrate with copper nanoparticle coatings at atmospheric pressure, in terms of critical heat flux (CHF) and heat transfer coefficient (HTC). Experiments are carried out on the substrate surface with a diameter of 12 mm using DI water as the working fluid. The coating is formed by stacking copper nanoparticles generat
8000 years ago, prior to Neolithic agriculture, Europe was mostly a wooded continent. Since then, its forest cover has been progressively fragmented, so that today it covers less than half of Europe's land area, in many cases having been cleared to make way for fields and pasture-land. Establishing the origin of Europe's current, more open land-cover mosaic requires a long-term perspective, for wh
The interaction of CO with the Fe3O4(001)-(√2 × √2)R45° surface was studied using temperature-programmed desorption (TPD), scanning tunneling microscopy (STM), and X-ray photoelectron spectroscopy (XPS), the latter both under ultrahigh vacuum (UHV) conditions and in CO pressures up to 1 mbar. In general, the CO-Fe3O4 interaction is found to be weak. The strongest adsorption occurs at surface defec
A single bout of electroacupuncture results in muscle contractions and increased whole body glucose uptake in women with polycystic ovary syndrome (PCOS). Women with PCOS have transcriptional and epigenetic alterations in the adipose tissue and we hypothesized that electroacupuncture induces epigenetic and transcriptional changes to restore metabolic alterations. Twenty-one women with PCOS receive
Hydrogen, carbon, and oxygen are common unintentional impurities of Al(x)Ga(1−x)N crystals. This impurity structure and its interplay with Mg impurities in Al(x)Ga(1−x)N semiconductors are relevant to develop the p-type nitride crystals for various devices (e.g, LEDs, transistors, gas sensors) but are still unclear. Here we have investigated Mg-doped Al0.5Ga0.5N before and after postgrowth anneali
During early literacy skills development, rhyming is an important indicator of the phonological precursors required forreading. To determine if neural signatures of rhyming are apparent in early childhood, we recorded event-relatedpotentials (ERPs) from 3- to 5-year-old, preliterate children (N = 62) in an auditory prime-target nonword rhymingparadigm (e.g., bly-gry, blane-vox). Overall, nonrhyminDuring early literacy skills development, rhyming is an important indicator of the phonological precursors required for reading. To determine if neural signatures of rhyming are apparent in early childhood, we recorded event-related potentials (ERPs) from 3- to 5-year-old, preliterate children (N = 62) in an auditory prime-target nonword rhyming paradigm (e.g., bly-gry, blane-vox). Overall, nonrhy
Lysosomal membrane permeabilization (LMP) contributes to tissue involution, degenerative diseases, and cancer therapy. Its investigation has, however, been hindered by the lack of sensitive methods. Here, we characterize and validate the detection of galectin puncta at leaky lysosomes as a highly sensitive and easily manageable assay for LMP. LGALS1/galectin-1 and LGALS3/ galectin-3 are best suite
Working within the Langevin framework of nuclear shape dynamics, we study the dependence of the evolution on the degree of excitation. As the excitation energy of the fissioning system is increased, the pairing correlations and the shell effects diminish and the effective potential-energy surface becomes ever more liquid-drop like. This feature can be included in the treatment in a formally well-f
Background/Aim: Streptococci cause approximately 10% of prosthetic joint infections (PJIs). The aim of this study was to identify the characteristics of patients with streptococcal PJIs and to describe the treatment and outcome of streptococcal PJIs in Skåne county between 2011 and 2015. Methods: Patients with streptococcal PJIs with positive cultures or PCRs on samples from joint aspirate and/or
Objective: To study whether locally administered recombinant inactivated human coagulation factor VIIa (FFR-rFVIIa) would reduce the thrombus formation and improve patency in an experimental venous thrombosis model without inducing systematic changes in the coagulation. Design: Experimental double-dummy randomised study. Materials: In 20 healthy New Zealand White rabbits both juguIar veins were ex
The structures of Ruddlesden-Popper n = 2 member phases Sr3-xYxFe125Ni0.75O7-δ with 0 ≤ x ≤ 0.75 have been investigated using neutron powder diffraction and K-edge Fe and Ni EXAFS/XANES spectroscopy in order to gain information about the evolution of the oxygen vacancy distribution and Fe/Ni oxidation state with x. Both samples prepared at 1300°C under a flow of N2(g), with δ = 1.41-1.00, and samp
The applicability of the Weibull distribution to model the strength of glass, the existence of a size effect on the strength and the need for a non-destructive testing of the strength are discussed and reviewed. There are a growing number of studies that put into question the applicability of the Weibull distribution to model annealed glass fracture data. A recent study indicates that the breakage
Renovating and improving the current building stock is a matter of both need and importance. In order to know if the implemented renovation measure has had an impact on the building as a system it is important to verify the impact through measurements. The aim of this project is to isolate the impact of a measure on the energy efficiency of a building as well as the indoor environmental quality. T
We report the identification of a new family of proteins, termed the HEM family, which show distinct expression patterns in blood cells and the central nervous system. Through the isolation and characterization of the corresponding brain-specificDrosophila(dhem-2) and rat orthologues (Hem-2), and through the detection of theCaenorhabditis elegansHem-2 orthologue in the database, we show that this
Pulmonary sarcoidosis was studied with respect to lung mechanical properties and to the influence of these on lung volumes. Sixty six patients, with histological support for the diagnosis of sarcoidosis, and radiological signs of pulmonary involvement, i.e. stage II or III, were studied. The static pressure/volume (P/V) curves showed that the static elastic recoil pressure (PelL) tended to be incr
Intravesical inoculation of gram negative bacteria or isolated bacterial products into mice induces an IL-6 response which can be measured within miutes of the infection.1,2 In such infections, IL-6 is initially detected in the urine and subsequently in the serum. Similar IL-6 responses were found in human patients deliberately colonized in the urinary tract with E. coli Hu7343. IL-6 was secreted
