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Hela människor handlar om mötet med patienten i behandling av psykisk ohälsa. Perioden är sent 1700-tal till 1924, en tid av revolutionerande förändringar både i tolkningen och hanteringen av psykiskt lidande. En rad behandlingstraditioner växte fram, var och en med sina egna teorier om vad sjukligheten kunde bero på och hur den skulle bemötas. Några traditioner lever kvar i dag, som allmänmedicin
Mice harbor ∼2800 intact copies of the retrotransposon Long Interspersed Element 1 (L1). The in vivo retrotransposition capacity of an L1 copy is defined by both its sequence integrity and epigenetic status, including DNA methylation of the monomeric units constituting young mouse L1 promoters. Locus-specific L1 methylation dynamics during development may therefore elucidate and explain spatiotemp
BACKGROUND: LINE-1 (L1) retrotransposons are a notable endogenous source of mutagenesis in mammals. Notably, cancer cells can support unusual L1 retrotransposition and L1-associated sequence rearrangement mechanisms following DNA damage. Recent reports suggest that L1 is mobile in epithelial tumours and neural cells but, paradoxically, not in brain cancers.RESULTS: Here, using retrotransposon capt
Hydrogen sulfide (H2S), an environmentally harmful pollutant, is a byproduct of geothermal energy production. To reduce the H2S emissions, H2S-charged water is injected into the basaltic subsurface, where it mineralizes to iron sulfides. Here, we couple geophysical induced polarization (IP) measurements in H2S injection wells and geochemical reactive transport models (RTM) to monitor the H2S stora
β-lactam antibiotics represent a novel direction in the chemotherapy of tuberculosis that brings the peptidoglycan layer of the complex mycobacterial cell wall in focus as a therapeutic target. Peptidoglycan stability in Mycobacterium tuberculosis, especially during infection, relies on the nonconventional peptide cross-links formed by l,d-transpeptidases. These enzymes are known to be inhibited b
We investigated the role of phosphorus (P) impurities on the fracture toughness and underlying failure mechanisms by means of classical atomistic modeling for a set of ⟨110⟩ symmetric tilt tungsten grain boundaries (GBs). This entailed the utilization of a quasi-static mode I displacement-controlled setup with cohesive zone volume elements (CZVEs) to study failure mechanisms and evaluate the fract
This thesis examines Flatus lifir, a widely recognized phenomenon in Iceland’s rural public space. Located in Kollafjörður on the outskirts of Reykjavík, the work has existed in several different forms over time and has become embedded within Icelandic public memory and popular culture. It appeared as an anonymous graffiti tag decades ago and later evolved into three distinct mural iterations in t
The modern construction industry is heavily resource-intensive, generating billions of tons of waste annually and contributing significantly to global carbon emissions. While recycling initiatives have grown, low-grade demolition debris such as broken bricks are systematically downcycled rather than reintegrated into structural architectural components due to their inherent heterogeneity and irreg
In Chinese fan fiction communities, the reporting button was made for flagging inappropriate content, but it has become a weapon in community conflict. An anonymous report can trigger removal or suspension, and those affected receive little explanation of how the decision was made. This thesis names this phenomenon weaponised reporting and asks how it operates and how targets pursue remedies under
Smygehus havsbad, en stor konferens-, spa-och hotellanläggning som började byggas vid förra sekelskiftet. Anläggningen består av flera olika byggnader som har byggts och renoverats i olika etapper genom åren. I gamla byggnader finns det ofta, med dagens mått, en bristfällig energiprestanda. Med anledning av ökade energipriser och klimattänk i beaktande har detta blivit allt mer märkbart. Det är dä
Despite the growing importance of Life Cycle Assessment (LCA) as a key tool to assess the environmental impact of products and services, many companies struggle with its implementation, lacking internal structures and capabilities to incorporate it into their operations. This thesis aims to understand the factors influencing companies' implementation of LCA, examining both drivers and barriers
Around the world, hard-won feminist progress is facing an organised and severe backlash. This thesis examines how formal feminist organisations in Kenya construct, defend, and sustain gender-justice narratives on Facebook amid a challenging "post-truth" digital landscape. Drawing on Nancy Fraser’s theory of subaltern counterpublics and employing digital ethnography, the study investigate
This thesis examines how survival is articulated and practiced within two queer community choirs in Malmö and Berlin. Situated within a European context marked by increasing anti-gender politics and queer precarity, the study conceptualizes queer survival as a collective and political practice grounded in care, resilience and futurity. Drawing on queer theory and queer political sociology, it expl
Zinc-Manganese dioxide (MnO₂) batteries have garnered significant interest due to their high energy density, low cost and low toxicity. Crystalline MnO₂ has shown structural transformations during the intercalation and deintercalation of Zn, which influences the performance of the battery. Recent studies have demonstrated that amorphous MnO₂ shows better Zn storage capacity due to an increase in s
Den ökade efterfrågan och turismen i Stockholms skärgård har skapat en identitetsmässig konflikt, där bebyggelseutvecklingen främst drivs av kommersiella besöksnäringar och privata fritidshus. Skärgårdsmiljön balanserar idag mellan strikt skyddade naturområden och exklusiva, privatiserade strandtomter, vilket lämnar lite utrymme för ett levande permanentliv. För att skärgården ska förbli en fungerThe growing demand and tourism in the Stockholm archipelago have created a conflict of identity, where property development is primarily driven by commercial hospitality industries and private seasonal housing. Today, the archipelago environment balances between strictly protected natural areas and exclusive, privatized shorelines, leaving little room for a vibrant, year-round community. For the a
Water loss is a crucial factor for vegetation in the semi-arid Sahel region of Africa. Global satellite-driven estimates of plant CO2 uptake (gross primary productivity, GPP) have been found to not accurately account for Sahelian conditions, particularly the impact of canopy water stress. Here, we identify the main biophysical limitations that induce canopy water stress in Sahelian vegetation and
Inputs of salt spray to the blanket bogs, due to their proximity to the coast and the predominant westerly winds from the Atlantic Ocean. To test this hypothesis we carried out an ecohydrological field study at a large blanket bog in the western part of Connemara, Ireland. We described peat profiles in two transects and sampled pore water from peat at different depths. The water samples were analy
