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Background: According to the literature the three stone diseases, sialolithiasis (SL), urolithiasis (UL) and cholelithiasis (CL) share comorbidities. We assess familial and spouse risks between these stone disease and compare them to familial risks for concordant (same) stone disease. Methods: Study population including familiar relationships was obtained from the Swedish Multigeneration Register
Tunnel field-effect transistors (TFETs) are designed for low off-state leakage and low drive voltages. To investigate how capable TFETs are of RF operation, we measured their scattering parameters and performed small-signal modeling. We find that in the low frequency ranges, gate oxide defects have a major influence on the RF performance of these devices, which can be modeled by a frequency-depend
The study aim was to explore the relationship between a developmental assessment at preschool age and an intelligence quotient (IQ) assessment at school age. One hundred sixty-two children were assessed at 2.5 years with the Bayley Scales of Infant and Toddler Development—Third Edition (Bayley-III) and then at 6.5 years with the Wechsler Intelligence Scale for Children—Fourth Edition (WISC-IV). Th
To further improve the flat-type loop heat pipe (LHP) performance, this study evaluates the practical potential of use of highly enhanced boiling structures. It is found that in our proposed new heat pipe (NHP) system, the working fluid from the evaporator outlet to the condenser inlet is in a liquid–vapor two phase flow, which is different from the classical LHP theory. A new P-T diagram is devel
Background NLRC5 is an interferon γ-inducible protein, which plays a role in immune surveillance with a potential influence on cancer survival. Objective We aimed to evaluate the effect of potential regulatory variants in NLRC5 on overall survival and survival after 5-fluorouracil (5-FU)-based therapy of colorectal cancer (CRC) patients. Patients and methods We carried out a case-only study in a C
Cyclical heat engines are a paradigm of classical thermodynamics, but are impractical for miniaturization because they rely on moving parts. A more recent concept is particle-exchange (PE) heat engines, which uses energy filtering to control a thermally driven particle flow between two heat reservoirs1,2. As they do not require moving parts and can be realized in solid-state materials, they are su
Whole-genome sequencing methods in familial cancer are useful to unravel rare clinically important cancer predisposing variants. Here, we present improvements in our pedigree-based familial cancer variant prioritization pipeline referred as FCVPPv2, including 12 tools for evaluating deleteriousness and 5 intolerance scores for missense variants. This pipeline is also capable of assessing non-codin
Familial risk of ovarian cancer is well-established but whether ovarian cancer clusters with other cancers and the clusters differ by histology remains uncertain. Using data from the Swedish Family-Cancer Database, we explored familial associations of ovarian cancer with other cancers with a novel approach; relative risk for (histology-specific) ovarian cancer was estimated in families with patien
Steady-state laminar natural convection of Cu and TiO2 nanofluids inside different enclosures is numerically investigated. Natural convection is concerned due to a temperature difference between the hot and cold surfaces. The Boussinesq approximation is used to form the governing equations and the commercial software package ANSYS FLUENT version 14.0 is used to numerically solve the governing equa
GaxIn(1−x)P nanowire arrays are promising for various optoelectronic applications with a tunable band-gap over a wide range. In particular, they are well suited as the top cell in tandem junction solar cell devices. So far, most GaxIn(1−x)P nanowires have been synthesized by the use of trimethylgallium (TMGa). However, particle assisted nanowire growth in metal organic vapor phase epitaxy is typic
This thesis explores the transport of thermally and optically excited electrons invarious nanowire structures. On one hand, electrons are thermally excited when thetemperature is nonzero, and the thermal energy help them surmount energy barriersthat are present in the material. On the other hand, when the electron distributionsat different part of the material are out-of-equilibrium due to thermal
Background: Although advances in the treatment of myeloid neoplasms have led to improved patient survival, this improvement has been accompanied by an increased risk of second primary cancer (ie, the risk of another cancer after myeloid neoplasia). We aimed to assess bi-directional associations between myeloid cancers and other cancers—ie, development of second primary cancer in patients who have
We investigate the Josephson radiation of nanowire (NW)-based Josephson junctions in a parallel magnetic field. The Josephson junction made of an InAs NW with superconducting Al leads shows the emission spectra which follow the Josephson frequency over the range 4-8 GHz at zero magnetic field. We observe an apparent deviation of the emission spectra from the Josephson frequency which is accompanie
In the primary school classroom, children are exposed to multiple factors that combine to create adverse conditions for listening to and understanding what the teacher is saying. Despite the ubiquity of these conditions, there is little knowledge concerning the way in which various factors combine to influence listening comprehension and the effortfulness of listening. The aim of the present study
Due to the ability to manipulate photons at nanoscale, plasmonics has become one of the most important branches in nanophotonics. The prerequisites for the technological application of plasmons include high confining ability (λ0/λp), low damping, and easy tunability. However, plasmons in typical plasmonic materials, i.e., noble metals, cannot satisfy these three requirements simultaneously and cau
Aims: This study investigates the lobbying actors of the food and drink industry (FDI), their web lobbying arguments used in the sugar taxation debate and the tactics deployed when facing legislative restrictions on their products to curb the burden of non-communicable diseases in Europe. Methods: A stakeholder analysis was performed to identify the FDI’s actors lobbying against sugar taxation wit
In this thesis, we study quantum transport properties of superconductor-semiconductor nanowire hybrid devices. We mainly focus on the quantum transport in InSb nanowire Josephson quantum dot devices, i.e. quantum dots coupled to two pieces of superconductors. In such a structure, many-body interacting phenomena occur, such as Kondo correlation, multiple Andreev reflection, and the formation of And
The thermophysical properties of the ionic liquid, 1-butyl-3-methylimidazolium bis{(trifluoromethyl)sulfonyl}imide, [C4mim][NTf2], at medium temperature, were predicted based on a summary of previous literature data. Furthermore, the heat transfer behavior in smooth and corrugated tubes was numerically studied, using different fluid temperatures and corrugation heights. A multi-objective optimizat
IMPORTANCE Prostate cancer commonly metastasizes to bone, and bone metastases are associated with pathologic fractures, pain, and reduced survival. Bone disease is routinely visualized using the technetium Tc 99m(99mTc) bone scan; however, the standard interpretation of bone scan data relies on subjective manual assessment of counting metastatic lesion numbers. There is an unmet need for an object
Background: Based on the possible shared mechanisms of chemotherapy-induced peripheral neuropathy (CIPN) for different drugs, we aimed to aggregate results of all previously published genome-wide association studies (GWAS) on CIPN, and to replicate them within a cohort of multiple myeloma (MM) patients. Methods: Following a systematic literature search, data for CIPN associated single nucleotide p
