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Endwall film cooling is a significant cooling method to protect the endwall region and the junction region of endwall and a turbine vane, where usually a relatively high temperature load exists. This work aims to find the optimized arrangement of film cooling holes on the endwall and improve the film cooling in some difficult regions on the endwall, such as pressure side-endwall junction region. S
Objectives: To carry out genetic and serological analyses of a Swiss blood donor and a Danish patient carrying an aberrant ABO phenotype with weak A expression. Background: ABO is the most clinically important blood group system but also one of the most complex. The system antigens are determined by carbohydrate structures generated by A and B glycosyltransferases encoded by the ABO gene. Genetic
Endwall film cooling upstream of the leading edge (LE) of a vane presents a relatively complex flow phenomenon due to the horseshoe vortices (HVs) generated at the LE region. Upstream of the LE region, the coolant flow has difficulties to eject out. This research work focuses on controlling the jet holes coolant coverage upstream of the LE region. Compound angle holes in staggered arrangement are
Laterally grown InxGa1-xAs nanowires (NWs) are promising candidates for radio frequency and quantum computing applications, which, however, can require atomic scale surface and interface control. This is challenging to obtain, not least due to ambient air exposure between fabrication steps, which induces surface oxidation. The geometric and electronic surface structures of InxGa1-xAs NWs and conta
CONCLUSIONS: This update on the P1PK blood group system (Hellberg Å, Westman JS, Thuresson B, Olsson ML. P1PK: the blood group system that changed its name and expanded. Immunohematology 2013;29:25-33) provides recent findings concerning the P1PK blood group system that have both challenged and confirmed old theories. The glycosphingolipids can no longer be considered the sole carriers of the anti
We present the first one-step acoustic separation of high quality plasma and mononuclear cells (MNCs) from undiluted human whole blood. This enables centrifugation-free integration in analytical instrumentation.
Down to a cathodic potentials of -1.20 V versus the reversible hydrogen electrode, the structure of IrO2(110) electrodes supported by TiO2(110) is found to be stable by in situ synchrotron-based X-ray diffraction. Such high cathodic potentials should lead to reduction to metallic Ir (Pourbaix diagram). From the IrO2 lattice parameters, determined during cathodic polarization in a H2SO4 electrolyte
In this work, a fast and efficiently design method has been introduced. This design process consists of the overall design and the detailed design. For the overall design, one-dimensional pipe-network computations are employed to obtain several design cases quickly at the beginning. Meanwhile the solid domain geometry and mesh with cooling structures, i.e., film holes, impingement holes, and ribs
It is unclear whether caregiving has an impact on the physical, mental and functional health of older caregivers. This study aimed to describe physical, mental and functional health in relation to family caregiving in old age (60+) over a six-year period. The study comprised 2,294 randomly selected individuals (60–96 years) from the Swedish National Study on Aging and Care, who answered the questi
An international consensus on antineutrophil cytoplasm antibodies (ANCA) testing in eosinophilic granulomatosiswith polyangiitis (EGPA) is presented.ANCA, specific formyeloperoxidase (MPO), can be detected in 30-35% of patients with EGPA. MPO-ANCA should be tested with antigen-specific immunoassays in any patient with eosinophilic asthma and clinical features suggesting EGPA, including constitutio
Background: Distal radius fractures can adversely affect wrist function; for men with this fracture, the role played by fracture severity, age and osteoporosis on fracture outcome has not been sufficiently studied. Objective: To describe patient-reported outcome and the association with bone integrity, fracture severity and future fracture risk among young and older men with distal radius fracture
Det betraktas ofta som en självklarhet att skillnaden mellan den verkliga och budgeterade kostnaden blir betydande vid genomförande av byggprojekt. Fastställd projektbudget innehåller uppenbarligen ofta ofullständigheter, kostnadsposter saknas, omfattning/krav ökar i under hand på vad som skall byggas i det kommande projektet. För att kunna göra en korrekt budget, där kalkylen överensstämmer med s
Countering the effects of human-induced environmental threats around the world is more urgent than ever. At the same time the power of companies has increased in the last decades. Activities of companies are capable of affecting human health negatively and in some cases the effects are so severe as to give rise to human rights violations. The question that is asked in this thesis is whether this p
Background and purpose: Molecularly targeted cancer therapies challenge conventional health economic evaluation frameworks that are structured around tumour-specific indications, comparators, and trial designs. Existing models often rely on pooled estimates from heterogeneous early-phase evidence or single-indication analyses, creating uncertainty for reimbursement decision-makers. We propose a co
Background The aim of this systematic review and meta-analysis was to examine autoantibody positive individuals and define: (a) the relative risk of rheumatoid arthritis (RA) compared with autoantibody negative individuals and (b) the cumulative incidence of RA over time, in different populations. Methods A systematic literature search was performed in August 2025. Retrospective case control studi
Background: Cohort studies often use simple models, for example, completers-only or aggregated scores, to assess changes in imaging outcomes. With more data available, this introduces selection bias. Integrated analyses allow scores from multiple reading rounds; therefore, we assessed their effect on the change estimates’ precision compared with the completers-only analysis. Second, we compared ch
