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Despite new therapies, castration-resistant prostate cancer (CRPC) is still incurable. Intercellular Adhesion Molecule 1 (ICAM-1) is a well-characterized cell surface protein involved in prostate cancer pathogenesis, differentially expressed during transition from hormone-sensitive to CRPC. This study aimed to investigate ICAM-1 as a target for imaging and radioimmunotherapy of CRPC.Anti-ICAM-1 an
Spatial Data Infrastructure (SDI) development is widely known to be a challenging process owing to its complex and dynamic nature. Although great effort has been made to conceptually explain the complexity and dynamics of SDIs, few studies thus far have actually modeled these complexities. In fact, better modeling of SDI complexities will lead to more reliable plans for its development. A state-of
Background: Biodiesel is the main liquid biofuel in the EU and is currently mainly produced from vegetable oils. Alternative feedstocks are lignocellulosic materials, which provide several benefits compared with many existing feedstocks. This study examined a technical process and its mass and energy balances to gain a systems perspective of combined biodiesel (FAME) and biogas production from str
Can civil society simultaneously be duty-bearers and rights-holders? In global human rights discourse, the term 'civil society' is commonly used in two seemingly opposing ways. The first is the use of 'civil society' as denoting an extended duty-bearer in the form of non-governmental organisations (NGOs) which by many states across the world are being tasked with directly implementing human rights
Advantages and disadvantages of anonymisation of assessment procedures have been discussed for decades. It is not difficult to understand why the issue has been on the agenda for such a long time. To a large extent, both in Sweden and internationally, it is the students who request anonymisation in examination procedures, and their demands stem from a concern about bias in assessment and grading.
Structural Health Monitoring (SHM) provides real-time information about structural damage and its evolution over time, which supports decision-makers in managing structural integrity. However, traditional SHM systems, such as vibration-based systems with accelerometers, require laborious installation and maintenance of instrumentation, including sensors, cables, and acquisition systems directly in
Background Evidence-based medicine recognizes that clinical expertise gained through experience is essential to good medical practice. However, it is not known what beliefs clinicians hold about how personal clinical experience and scientific knowledge contribute to their clinical decision making and how those beliefs vary between professions, which themselves vary along relevant characteristics, Background: Evidence-based medicine recognizes that clinical expertise gained through experience is essential to good medical practice. However, it is not known what beliefs clinicians hold about how personal clinical experience and scientific knowledge contribute to their clinical decision making and how those beliefs vary between professions, which themselves vary along relevant characteristics,
Methods: Drug-induced interstitial lung disease (ILD) is crucial to detect early to achieve the best treatment outcome. Optimally, non-invasive imaging biomarkers can be used for early detection of disease progression and treatment follow-up. Therefore, reliable in vivo models are warranted in new imaging biomarker development to accelerate better-targeted treatment options. Single-dose bleomycin
Externally bonded fiber-reinforced polymer (FRP) plates or sheets have become a common retrofitting approach for sustaining old reinforced concrete structures in the modern era. The capacity of FRP-strengthened structures cannot be accurately estimated because the bond strength between FRP and concrete surface is accurately unpredictable. Various studies are available in the literature to predict
Aim: To investigate psychosocial factors in painful TMD (pTMD) which could have consequences for mastering chronic pain. Methods: Our study included 22 patients (20 women, 2 men) with pTMD, refractory to conservative treatment, and 19 healthy controls. The control group was matched for gender, age, and educational level, and IQ tested on the Wechsler Abbreviated Scale of Intelligence. Neurocogniti
X-ray ptychography is often implemented for nanoimaging at synchrotron radiation sources and extensions are being developed to make experiments faster. This work is on multi-beam ptychography with Fresnel zone plates that have a small lateral separation, enabling the imaging of an extended field of view without increasing exposure time. Sectional zone inversion is implemented for coding respective
This study investigated if clothing material with reflective properties has an effect on heat gain in pilot, specifically, under solar radiation. Two materials, conventional pilot suit material (Old) and material coated with coldblack® (New, Schoeller Technologies AG, Switzerland) were tested over variety of underwear layers and in a box simulating cockpit. A hot plate was used to measure textile
Abstract not available
Detta utkast utgör en redovisning av ett uppdrag som jag fick av Forsknings- och utvecklingsenheten vid Statens institutionsstyrelse (SiS). Uppdraget bestod i att, under en tvåmånadersperiod (april och maj 2009), granska och urskilja etnicitetsmarkörer i det empiriska material som samlats in under intervjuer och möten med aktörerna i ett samarbetsprojekt i ungdomsvården (MVG-projektet). Tanken var
Commentary and analysis of the proposal of the Swedish Ministry of Justice (Ds 2021:30) concerning implementation of Article 17 Directive 2019/790 on copyright and related rights in the Digital Single Market (DSM Directive). Part 1 of 2.
To investigate if left and right atrioventricular plane displacement (AVPD) or regional contributions to SV are prognostic for outcome in patients with pulmonary arterial hypertension (PAH). Seventy-one patients with PAH and 20 sex- and age-matched healthy controls underwent CMR. Myocardial borders and RV insertion points were defined at end diastole and end systole in cine short-axis stacks to co
