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Several immunodeficiency-related genes are known and a numb er of disease causing mutations have been identified. Immunodeficiency related mutation information have been collected into IDbases. We are currently maintaining 15 registries, which are available at http://www.uta.fi/imt/bioinfo/. The databases are available for the following disorders: adenosine deaminase, CD3 epsilon, CD3 gamma, JAK3,
Behandlar gipsavgjutningarnas ställning och roll i konstutbildningen och på konstmuseerna från 1700-talet till 1914.
Purpose: To investigate the inflammatory response of current and future potential vitreous substitutes in an experimental in vivo vitrectomy model. Methods: Twenty-five gauge pars plana vitrectomy was performed in the right eye of 60 pigmented rabbits, with subsequent injection of 0.5–1.0 ml of Healaflow® (cross-linked hyaluronic acid, n = 12), Bio-Alcamid® (polyalkylimide, n = 8), silicone oil (n
This paper provides an empirical analysis of the effectiveness of real-time feedback technology in the Swedish residential sector. We take the ‘100Koll’ service provided by one the largest energy companies in Sweden as a case study. Based on an intervention group (i.e. people using the service) of 1 753 households, a survey was carried out to explore behavioural, moral, socio-economic and contextu
Direct and precise manipulation of sub-micron particles such as bacteria, platelets, organelles, microvesicles, exosomes or virus particles is challenging. We describe for the first time how acoustic streaming in the bulk can be efficiently reduced by introducing a density or compressibility gradient and that this enables focusing of 500-nm-diameter particles in a standard acoustophoresis channel.
Ever since Goldin-Meadow, S., C. Mylander, W. C. So, and A. Özyürek. 2008. The natural order of events: How speakers of different languages represent events nonverbally. PNAS 105: 9163–9168. proposed that there is a preferred order in sequential non-verbal event representations (Actor > Patient > Act), apparently independent of the default word order in one’s native language, the topic has been th
The workshop brings together differing perspectives on what makes research data possible. How data is made represents an on-going negotiation between a number of elements. It reflects, firstly, the nature of disciplines and thecomplex way this is linked to cultures of research data and data sharing. Secondly, data is made across the complex temporalities within different practices of its managemen
INTRODUCTION: Hyperactivity of the hypothalamic-pituitary-adrenal (HPA)-axis is a common finding in major depressive disorder. Similar studies on suicide attempters are less abundant, and the results are divergent. The main aim of the present study was to investigate HPA-axis parameters by the time of a suicide attempt and at follow-up in search for associations between HPA-axis function and suici
We have recently described the immunosuppressive properties of AR-C117977 and AR-C122982, representatives of a group of compounds identified as inhibitors of lactate transporters (monocarboxylate transporters; MCTs). These compounds demonstrate the potential therapeutic usefulness of inhibiting MCT-1, but their physical and metabolic properties made them unsuitable for further development. We have
Spatial models, such as the Besag, York and Mollie (BYM)model, have long been used in epidemiology and disease mapping. A commonproblem in these subjects is the modelling of number of disease eventsper region; here the BYM models provides a holistic framework for bothcovariates and dependencies between regions.We use these tools to assess the relative insurance risk associated withthe policyholder
I en studie av neutralisationskapaciteten och kalkstenshalten i Sydvattens infiltrationsområde vid Vomb har fem prover från olika platser i fältet samlats in, siktats och surgjorts med saltsyra. Neutralisationskapaciteten mätt som kalciumkarbonathalt befanns variera i de olika sandproverna men var generellt hög (ca 2–14 % som vikt). Den totala massan av kalciumkarbonat i infiltrationsområdet bestäIn a study of the neutralization capacity and limestone content the artificial recharge area of the Sydvatten waterworks Vombverket in Vomb, Skåne, five samples from different locations in the area was collected, sieved and acidified with hydrochloric acid. The neutralization capacity measured as calcium carbonate content was found to vary in the different sandy soil samples but was generally high
Some people react to smells or chemicals at levels far below toxicological thresholds with nonspecific symptoms, fear and social isolation. They may be diagnosed with multiple chemical sensitivity. There is no empirical evidence indicating that this condition is explained by toxicological mechanisms, even though a number of theories have been proposed. The authors of this review conclude that this
