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We are facing a climate and ecological emergency. On all levels in society and the economy, there is a need to work towards climate neutrality and sustainable development. A key way to address global and local complex challenges is through cities. But how can we design, create and achieve climate neutral and sustainable cities? This compendium focuses on how to support individuals and organisation

Astrocytes are emerging key players in neurological disorders. However, their role in disease etiology is poorly understood owing to inaccessibility of primary human astrocytes. Pluripotent stem cell-derived cells fail to mimic age and due to their clonal origin do not mimic genetic heterogeneity of patients. In contrast, direct conversion constitutes an attractive approach to generate human astro

Prior research has shown that companies in various industrial contexts need to achieve both exploitation of current knowledge and technologies to make profits today, and exploration of new knowledge and technologies to adapt to changing conditions and prepare for tomorrow’s demands. The capacity to achieve both exploration and exploitation is especially problematic in project based organizations d

In 1798 the Royal Academy of Science instituted a classification of its members, designating the last class to be filled by those engaged with world of learning and beautiful arts. This study maps the population of this “erudite class” and analyzes the negotiation of epistemic virtues and merits linked to the nebulous field from which the class drew its members. The article argues that a previous

Type 2 diabetes (T2D) is caused by insufficient insulin secretion from pancreatic β-cells. To identify candidates contributing to T2D pathophysiology, we studied human pancreatic islets from ~300 individuals. We found 395 differentially expressed genes (DEGs) in islets from individuals with T2D, including, to our knowledge, novel (OPRD1, PAX5, TET1) and previously identified (CHL1, GLRA1, IAPP) ca

BACKGROUND: Very few studies have investigated whether unilateral choanal atresia is associated with permanent olfactory deficits.OBJECTIVE: This study aimed to evaluate the olfactory performance of patients with unilateral choanal atresia postsurgically.METHODS: Three patients with unilateral atresia were examined in terms of olfactory performance with the Sniffin' Sticks test (odor identificatio

Background: Co-cultures and cell immobilization have been used for retaining biomass in a bioreactor, with the aim to improve the volumetric hydrogen productivity (QH2). Caldicellulosiruptor kronotskyensis is a strong cellulolytic species that possesses tāpirin proteins for attaching on lignocellulosic materials. C. owensensis has its reputation as a biofilm former. It was investigated whether con

The great variety of earth's microorganisms and their functions are attributed to the heterogeneity of their habitats, but our understanding of the impact of this heterogeneity on microbes is limited at the microscale. In this study, we tested how a gradient of spatial habitat complexity in the form of fractal mazes influenced the growth, substrate degradation, and interactions of the bacterial st

Soot, or black carbon (BC), aerosol is a major climate forcer with severe health effects. The impacts depend strongly on particle number concentration, size and mixing state. This work reports on two field campaigns at nearby urban and rural sites, 65gkm apart, in southern Sweden during late summer 2018. BC was measured using a single-particle soot photometer (SP2) and Aethalometers (AE33). Differ

While the concept of hybridisation(blending of different organisational forms, logics, or identities) in public administration has gained traction, its interplay with principal‐agent dynamics, especially within developmentcooperation, remains underexplored. Recent shifts towards the “whole‐of‐society”paradigmin Swedish development cooperation introduce complexities in the inter‐organisational dyn

Aim: To explore nurses’ experiences of using the Integrated Palliative care Outcome Scale (IPOS) as a communication tool in specialized palliative care. Design: This study employed a qualitative inductive approach. The Standards for Reporting Qualitative Research were followed for reporting. Methods: Five focus groups were conducted with nurses from four specialized palliative care units, and the

The role of consumers in a circular economy (CE) is crucial but not well understood in the literature. For consumers to become catalysts in a CE, people need to understand how and under what conditions circular consumption is made possible. This chapter conceptualises the sociomaterial assembling of circular consumption, which refers to the process in which heterogeneous elements – meanings, mater

BackgroundThe risk of developing Alzheimer’s disease (AD) is modulated by genetic and environmental factors. Early-life stress (ELS) exposure during critical periods of brain development can impact later brain function and health, including increasing the risk of developing AD. Microglial dysfunction and neuroinflammation have been implicated as playing a role in AD pathology and may be modulated

The Swedish National Library published together with the university libraries in Gothenburg, Lund, Stockholm, Umeå and Uppsala in January 2020 a Declaration of Intent where the goal to digitiz Swedish print from the 15th century until today was formulated. Based on this objective, the article discusses different digitization strategies in libraries. Mass digitization stands for the rapid digitizat