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As both public and private organizations are spending resources on fostering entrepreneurship, we have witnessed the emergence of an entrepreneurship industry. Using the entrepreneurship industry in Sweden as a case and example, this chapter provides an explorative analysis the emergence, manifestations and consequences of cultural ideals within this industry. The analysis reveals how the entrepre
Aquaporin-4 (AQP4) is the predominant water channel in the brain; it is enriched in astrocytic foot processes abutting vessels where it is anchored through an interaction with the dystrophin-associated protein (DAP) complex. Enhanced expression with concomitant mislocalization of AQP4 along astrocyte plasma membranes is a hallmark of several neurological conditions. Thus, there is an urgent need t
This study aims to analyse and compare the challenges and opportunities that refugees and asylum seekers experience in Sweden and South Africa along with the strategies they develop in relation to higher education. As both countries have undertaken a more restrictive refugee and asylum policy, this study hopes to contribute to the debate of inclusion and its challenges. The data-collection entails
Senescence was recently linked to neurodegeneration and astrocytes are one of the major cell types to turn senescent under neurodegenerative conditions. Senescent astrocytes were detected in Parkinson's disease (PD) patients' brains besides reactive astrocytes, yet the difference between senescent and reactive astrocytes is unclear. We aimed to characterize senescent astrocytes in comparison to re
En populärvetenskaplig biografisk artikel över Julius Freund, lektor i tyska vid Lunds universitet 1898–1902, och hans vidare öden som internerad "enemy alien" i Storbritannien under första världskriget och från Nazityskland fördriven judisk akademiker strax innan andra världskriget.
In atherosclerotic vascular disease, endothelial dysfunction is induced by risk factors such as arterial hypertension, hypercholesterolemia, and tobacco use. In fl ammatory mechanisms and in fl ammatory cytokines play important roles in all of these mechanisms, and the different steps in atherogenesis involve cytokines as in fl ammatory promoters, stimulating the expression of proatherogenic genes
Alzheimer's disease (AD) is a common dementia affecting a vast number of individuals and significantly impairing quality of life. Despite extensive research in animal models and numerous promising treatment trials, there is still no curative treatment for AD. Astrocytes, the most common cell type of the central nervous system, have been shown to play a role in the major AD pathologies, including a
Here, we describe the generation of an induced pluripotent stem cell (iPSC) line, from a male patient diagnosed with Parkinson's disease (PD). The patient carries a heterozygous variation p.A53T in the SNCA gene. Skin fibroblasts were reprogrammed using the non-integrating Sendai virus technology to deliver OCT3/4, SOX2, c-MYC and KLF4 factors. The generated iPSC line (CSC-32) preserved the mutati
Transboundary research collaborations (TRCs) are critical in supporting evidence-based actions to address complex global issues. However, there is still a lack of empirics, which would detail how TRCs are organised, how activities are facilitated, and how actors interplay. In this article, we address this gap through the evaluation of a North-South TRC against the 11 principles for TRCs by the Com
Preeclampsia (PE) is a pregnancy disorder associated with placental dysfunction and elevated fetal hemoglobin (HbF). Early in pregnancy the placenta harbors hematopoietic stem and progenitor cells (HSPCs) and is an extramedullary source of erythropoiesis. However, globin expression is not unique to erythroid cells and can be triggered by hypoxia. To investigate the role of the placenta in increasi
Muhammad Hejazi, deputy head of the Iranian Quds Force, is reported to have died of heart disease. However, a mysterious tweet hints that he might have been killed.
Lignin is one of the main components of plant cell walls, which provides mechanical support for plants and also contributes to resisting against plant pathogenic fungi. In the fruit industry, the lignin content can affect the quality of fruit. The biosynthesis of lignin involves a variety of enzymes, of which caffeoyl-CoA 3-O-methyltransferase (CCoAOMT) is a class of methyltransferases that plays
