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Results are presented of a search for any particle(s) decaying to six or more jets in association with missing transverse momentum. The search is performed using 1.34 fb(-1) of root s = 7TeV proton-proton collisions recorded by the ATLAS detector during 2011. Data-driven techniques are used to determine the backgrounds in kinematic regions that require at least six, seven or eight jets, well beyon
A search is presented for production of dark-matter particles recoiling against a leptonically decaying Z boson in 20.3 fb(-1) of pp collisions at root s = 8 TeV with the ATLAS detector at the Large Hadron Collider. Events with large missing transverse momentum and two oppositely charged electrons or muons consistent with the decay of a Z boson are analyzed. No excess above the Standard Model pred
A search for the Higgs boson has been performed in the H -> WW(*()) -> l+vl-(v) over bar channel (l = e/mu) with an integrated luminosity of 2.05 fb(-1) of pp collisions at root s = 7 TeV collected with the ATLAS detector at the Large Hadron Collider. No significant excess of events over the expected background is observed and limits on the Higgs boson production cross section are derived for a Hi
A search is presented for direct chargino production based on a disappearing-track signature using 20.3 fb(-1) of proton-proton collisions at root s = 8 TeV collected with the ATLAS experiment at the LHC. In anomaly-mediated supersymmetry breaking (AMSB) models, the lightest chargino is nearly mass degenerate with the lightest neutralino and its lifetime is long enough to be detected in the tracki
The ability of von Willebrand factor (VWF) to bind platelet GP Ib and promote platelet plug formation is measured in vitro using the ristocetin cofactor (VWF:RCo) assay. Automated assay systems make testing more accessible for diagnosis, but do not necessarily improve sensitivity and accuracy.
ObjectiveTo study the impact of swollen to tender joint count ratio (STR) and other baseline characteristics on treatment response to a first course of anti-tumor necrosis factor (anti-TNF) therapy in rheumatoid arthritis (RA) patients. MethodsPatients with RA initiating their first course of anti-TNF treatment were included in a structured clinical followup protocol. Based on pragmatic thresholds
Previous studies including various tumor types have shown different associations between tumor tissue levels of plasminogen activator inhibitor 2 (PAI-2) and patient survival. High tumor tissue concentrations of PAI-2 have been associated with good prognosis in patients with breast cancer, small cell lung cancer and ovarian cancer, but with poor histologic differentiation and poor prognosis in pat
Highly resolved pollen spectra analysed from a 47cm peat monolith recovered from a mire in northern Sweden exhibit climatic sensitivity in the pollen accumulation rates (PAR) of boreal treeline species. Robust temporal control, afforded through multiple AMS radiocarbon dating of the post atomic bomb-test period (AD1961-AD2002), provides a unique opportunity to compare pollen accumulation rates wit
Isochromosome 7q - i(7q) - is seen in a wide variety of hematologic malignancies and solid tumors, often as a secondary change to a characteristic primary translocation. Despite its high frequency, nothing is known about the formation and the pathogenetic outcome of this abnormality. To address these issues, we performed a detailed fluorescence in situ hybridization (FISH) investigation of four ac
The objective was to evaluate a screening procedure for detecting high-yield candidates for an OGTT, in a population of middle-aged Swedish women. A two-step screening procedure was performed in 6917 subjects. Women with a positive screening outcome, i.e. increased non-fasting capillary blood glucose, serum triglycerides, BMI, WHR, blood pressure or a family history of diabetes, pharmacological tr
Patients with osteoarthritis undergoing knee replacement have been reported to have an overall reduced mortality compared with that of the general population. This has been attributed to the selection of healthier patients for surgery. However, previous studies have had a maximum follow-up time of ten years. We have used information from the Swedish Knee Arthroplasty Register to study the mortalit
Hypoxia is common in many solid tumours, including breast cancer. Hypoxia triggers the expression of hypoxia inducible factor-1 alpha (HIF-1 alpha), and HIF-1 alpha has been associated with an impaired prognosis in breast cancer and down-regulation of the oestrogen receptor (ER), potentially affecting the treatment efficiency of antioestrogens. The role of HIF-1 alpha regarding prognostic and trea
Insulin stimulation of adipocytes results in serine phosphorylation/activation of phosphodiesterase 3B (PDE 3B) and activation of a kinase that phosphorylates PDE 3B in vitro, key events in the antilipolytic action of this hormone. We have investigated the role for p70 S6 kinase, mitogen-activated protein kinases (MAP kinases), and protein kinase B (PKB) in the insulin signaling pathway leading to
PURPOSE: As a prelude to developing updated, evidence-based, international consensus recommendations for the management of hip and knee osteoarthritis (OA), the Osteoarthritis Research Society International (OARSI) Treatment Guidelines Committee undertook a critical appraisal of published guidelines and a systematic review (SR) of more recent evidence for relevant therapies. METHODS: Sixteen exper
Introduction Manual interpretation of immunohistochemistry (IHC) is a subjective, time-consuming and variable process, with an inherent intra-observer and inter-observer variability. Automated image analysis approaches offer the possibility of developing rapid, uniform indicators of IHC staining. In the present article we describe the development of a novel approach for automatically quantifying o
Fungal laccases from Trametes hirsuta and Cerrena unicolor were immobilized on spectroscopic graphite electrodes using physical absorption. The laccase-modified graphite electrodes were mounted as the working electrodes into a wall jet flow through an electrochemical cell and then used for flow injection amperometric determination of different phenolic compounds of relevance both for environmental
The effect of a single washing of the urogenital tract with 0.5 g/l chlorhexidine was studied in 6 women in weeks 38-40 of pregnancy, among whom 5 were carriers of group B streptococci in urethra and/or cervix. The chlorhexidine concentrations varied between 25 and 200 mg/l during the first hour after washing in 5 of the 6 women, whereas one patient showed concentrations below 25 mg/l. With the ex
Arbetsgivarens möjlighet att beordra arbete på övertid är många gånger en nödvändighet för att verksamheten ska fungera. De senaste åren har det emellertid både rapporterats om ett högt övertidsuttag och en bristande psykosocial arbetsmiljö med hög arbetsbelastning inom flertalet branscher. I denna uppsats är syftet att utreda den rättsliga regleringen för övertids-uttag, där arbetsgivarens rätt aThe possibility for the employer to order overtime work can sometimes be necessary for the business to work. However, during the recent years it has been reported of both a high amount of overtime working hours, and an insufficient organizational and social work environment combined with a high workload, in several sectors of the labor market. This essay aims to investigate the legal regulation on
