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The ability of von Willebrand factor (VWF) to bind platelet GP Ib and promote platelet plug formation is measured in vitro using the ristocetin cofactor (VWF:RCo) assay. Automated assay systems make testing more accessible for diagnosis, but do not necessarily improve sensitivity and accuracy.
ObjectiveTo study the impact of swollen to tender joint count ratio (STR) and other baseline characteristics on treatment response to a first course of anti-tumor necrosis factor (anti-TNF) therapy in rheumatoid arthritis (RA) patients. MethodsPatients with RA initiating their first course of anti-TNF treatment were included in a structured clinical followup protocol. Based on pragmatic thresholds
Huvudsyftet med denna rapport är att söka samband mellan studieresultaten under det första läsåret vid de nya femåriga civilingenjörsprogrammen vid LTH och gymnasiebetygen – både det totala samt det i matematik. Sådana samband mellan gymnasiebetyg och resultat på första gemensamma matematiktentamen är tydliga – mer så för matematikbetygen från gymnasiet eftersom fler betyg i de lägre kategorierna
Carrier and prenatal diagnosis based on the identification of the gene defect (direct diagnosis) increases the proportion of haemophilia B families that can be offered precise genetic counselling from the 50-60% attainable by DNA markers, to 100%, and they also provide information on the molecular biology of the disease. We propose that in order to maximize the practical and scientific benefits of
Becoming alone in old age can be a decisive life event that brings major changes depending on various causes as health status, financial resources, family situation, and available welfare services. This article discusses the situation of older people in Sweden who have transitioned from a two-person to single-person household in recent years and what impact this might have on their everyday lives.
Background. Sampling of submucosal lesions in the gastrointestinal tract through a flexible endoscope is a well-recognized clinical problem. One technique often used is endoscopic ultrasound-guided fine-needle aspiration, but it does not provide solid tissue biopsies with preserved architecture for histopathological evaluation. To obtain solid tissue biopsies from submucosal lesions, we have const
We have searched for the simplest kaonic nuclear state, K̄NN, using the in-flight 3He (K-, n) reaction at the J-PARC hadron experimental facility. In the semi-inclusive neutron missing-mass spectrum at θnlab=0°, an excess of yield was observed just below the K- pp mass-threshold, which cannot be explained by any elementary reactions [PTEP 2015, 061D01]. To understand the missing-mass spectrum of 3
Creatine kinases are important in maintaining cellular-energy homeostasis, and neuroprotective effects have been attributed to the administration of creatine and creatine-like compounds. Herein we examine whether ablation of the cytosolic brain-type creatine kinase (B-CK) in mice has detrimental effects on brain development, physiological integrity or task performance. Mice deficient in B-CK (B-CK
BACKGROUND: Niemann-Pick disease type C (NP-C) is a rare neurovisceral disease characterised by progressive neurological degeneration, where the rate of neurological disease progression varies depending on age at neurological onset. We report longitudinal data on functional disease progression and safety observations in patients in the international NPC Registry who received continuous treatment w
I den här studien fördjupas förståelsen kring en grupp psykologers och kuratorers upplevelser om att vara i samtal med klienter, och om hur de påverkas av den sekundära psykiska påfrestningen som kan uppkomma då. Syftet med studien är att ta reda på vilka strategier de använder för att hantera svåra samtal, samt vilka strategier de använder för att bibehålla balansen mellan arbetsliv och privatlivThe results from this study deepens the understanding of how psychologists and welfare officers experiences therapeutical consultations with clients, and also how they are affected by the secondary mental stress that may occur. The objectives of the study are to examine which strategies the interviewees use to manage the impact difficult consultations may have on them selves, as well as which stra
Cambodian migrants in the Thai construction sector, work in precarious working environments, with limited safety conditions and low wages. The use of social protection schemes has increased in recent decades, as a method of reducing the vulnerable against poverty and livelihood risks. However, despite the transformative potential of social protection, migrant workers face difficulties in accessing
The purpose of this thesis is to examine how Sweden Democrats depicts the woman and analyzes if they use the woman to legitimize their policies. I do this by reconstructing the dominant narrative while striving to analyze how they legitimize the image of her and if they use her to legitimize their policies. The material that I use is the Sweden Democrats 'Principles Program (2011), the Swedish
This study employs an approach to policy as discourse and examines the construction of gender equality in the EU Gender Action Plan II. Drawing from the poststructural premise that discourses affect how issues are being thought about and acted upon, the study seeks to scrutinize how gender equality is attributed with meaning by applying Carol Bacchi’s analytical methodology What’s the problem repr
In studies surrounding the EU, assessments usually focus on the decision-making in the first tier-rule making system between the Commission, Parliament and the Council. What this study has analyzed is the second-tier rule making system, The Comitology. This institution is built up by hundreds of different committees tackling different subjects. Each committee is represented by one representative f
Corporations and in particular large multinational enterprises are important for every countries economic growth. However, exploitation and human rights abuses due to corporate activity are repeatedly occurring in states that lacks the proper legislation, enforcement or institutions to ensure human rights protection. Thus, there is an increasing call for lead firms of MNEs to exercise human rights
The development of policy instruments with the aim to support production of electricity from renewable sources is, and has been for the last decades,an important factor when working with global environmental challenges. Compared with other countries in the EU, Sweden ranks very high when referring to the development of renewable energy production. This thesis aims to examine the policy processes t
