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Action-detected 2D spectroscopy : Technical development and practical applications

This doctoral thesis presents a comprehensive investigation into action-detected two-dimensional electronic spectroscopy (A-2DES), from the technical development of a state-of-the-art apparatus to its application in elucidating ultrafast dynamics in advanced materials and biological systems. The work is founded on the design and implementation of an A-2DES setup centered on a single acousto-optic

Stimuli-Responsive Electronic Reconfiguration in Benzo(ghi)perylene-TCNQ Donor–Acceptor Crystalline Networks

Template-assisted crystal engineering provides a powerful strategy for constructing ordered networks tailored to organic electronic applications. We introduce a solution-based strategy to fabricate crystalline needle-like arrays of charge-transfer complexes (CTCs) between electron-donating benzo(ghi)perylene (BP) and electron-accepting TCNQ. Well-defined square-crystals of BP polymorphs were emplo

Segmentation of White Blood Cells Using Deep Learning

The white blood cell count and differential is an important part of diagnosing a number of medical conditions. Instead of doing this by manual microscopy, CellaVision’s technology has automated the process of finding and classifying white blood cells. To support a diagnosis it is desired that the system can produce cytoplasm-to-nucleus-ratio. This ratio is calculated from a segmented image where t

Palynostratigraphy and palaeoclimatic analysis of Lower-Middle Jurassic (Pliensbachian - Bathonian) of the Inner Hebrides, NW Scotland

Populärvetenskaplig samanfattning: Vid en palynologisk undersökning studeras syraresistenta mikrofossil, såsom pollen, sporer och vissa marina mikroplankton. Dessa används främst för att datera sedimentära bergarter men man kan även använda dem för att tolka miljö, vegetation och klimat under olika tidsavsnitt i jordens historia. Pollen och sporer är mycket beständiga mikrofossil och finns i lagerA palynostratigraphic investigation of partly ammonite dated, Pliensbachian to Bathonian (Early – Middle Jurassic) strata on the Isles of Skye and Raasay, Inner Hebrides in Northwest Scotland, has recovered a diverse but not always well preserved miospore flora and a less diverse dinoflagellate cysts flora. The studied interval has been subdivided into five biozones, A - E, based on the first occu

Medför de nya medierna nya möjligheter för arbetsgivaren att kontrollera illojalitet?

A very important aspect of the employees duty to the employer is to be loyal. The conflict between the freedom of speech and the employees loyalty duty is not new. However electronic trace like social media bring employees the possibility to present critics, disapproval and sometimes incorrect information to a large public. On the other hand the new technic also brings new possibilities to save th

Decay of a light pseudo-scalar Higgs boson to the Υ-meson and a photon

This paper is concerned with calculating the branching ratio of the decay A1 −→ Υ + γ of a pseudo-scalar Higgs boson, where Υ is a bound vector meson state of the quarks b and b-bar The results will then be applied to the b. phenomenology of the Next-to-Minimal Supersymmetric Standard Model in the case where A1 has a mass in the interval 9.46 − 12 GeV . The paper will review the concept of spontan

Targeted innate immune inhibition therapy compared with antibiotics for recurrent acute cystitis : a randomized, open-label phase 2 trial

Cystitis is a bacterial infection of the bladder that occurs in about half of women at least once in their lifetime. Antibiotics such as nitrofurantoin are used to treat cystitis, but antibiotic resistance is a concern, especially for recurrent infections. Here we report an open-label, randomized, single-centre, phase 2 study to analyse the acute and long-term safety and efficacy of the IL-1 recep

A point-of-care assay for genotyping women prior to ovarian stimulation with recombinant or human menopausal gonadotropins in assisted reproduction

Objective: Prior to in vitro fertilization (IVF), physicians can choose either recombinant or urine-derived follicle-stimulating hormone (FSH) for ovarian stimulation. The common polymorphism N680S (rs6166) in the follicle-stimulating hormone receptor (FSHR) has been linked to individual variability in ovarian response to FSH stimulation and IVF outcomes, including live birth rates, highlighting i

The Formal Model for Noctua pronuba (Lepidoptera, Noctuidae) representing a typical agricultural-landscape night-flying moth species for pesticide risk assessment

Nocturnal lepidopteran pollinators face pesticide exposure risks in agricultural landscapes, yet lack adequate risk assessment frameworks compared to diurnal species. We present a formal model description for Noctua pronuba within the Animal Landscape and Man Simulation System (ALMaSS), providing the first comprehensive agent-based framework for assessing the impacts of pesticides on nocturnal mot

Associations between activity limitations and participation restrictions in people with late effects of polio

Background: Late effects of polio (LEoP) are defined as new symptoms, for example, muscle weakness, fatigue, and pain, occurring many years after an acute polio infection. These impairments can lead to difficulties performing everyday activities (ie, activity limitations) that can reduce a person's ability to take part in society (ie, perceived participation restrictions). Yet, no study has explor

Histological analysis of age-related degeneration in human female and male knee cartilage and meniscus

Objectives: To assess level of degeneration in human knee cartilage and meniscus in donors without clinically-evident knee arthritis, in relation to age and sex. Further, to investigate the association between cartilage and meniscus degeneration. Design: Histological sections of knee cartilage and meniscus from 44 deceased donors (ages 18–85 years) without clinically-evident osteoarthritis or infl

COVID-19 outcomes in individuals with severe alpha-1 antitrypsin deficiency in Sweden

We have previously found using questionnaire/interview data on COVID-19 outcomes, that most subjects with severe alpha-1-antitrypsin deficiency (AATD) exhibit mild COVID-19 infection and those who additionally have COPD are at increased risk of severe COVID-19. We used objective information on COVID-19 outcomes in severe AATD (PiZZ) from the Swedish population and compared the risk of severe COVID

Decoding Wetting Behavior : Capillary Rise Experiments with Amphiphilic Compounds and Theoretical Aspects

Wetting and dewetting dynamics in aqueous solutions containing amphiphilic compounds involve intricate interactions that influence contact angles and surface tension, with broad implications in materials science and biology. This study explores the dynamics of wetting and dewetting on glass surfaces in aqueous media containing the amphiphilic compound C18OE84, focusing on capillary rise behavior.

Capsule Regulation Shapes Klebsiella pneumoniae Pathogenesis by Balancing Adhesion, Biofilm Formation, and Intracellular Survival

Klebsiella pneumoniae is a major opportunistic pathogen, where the polysaccharide capsule is traditionally recognized as a critical virulence determinant. However, its role in surface interactions and intracellular adaptation remains incompletely understood. Here, we combined phenotypic assays with physicochemical analyses to dissect the contribution of the capsule. A wza knockout mutant display