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Influence of the laser pulse duration in high-order harmonic generation

High-order harmonic generation (HHG) in gases is inherently inefficient, prompting ongoing efforts to enhance the output of coherent table-top XUV sources. In this study, we investigate the influence of the laser pulse duration on HHG using a compact post-compression method featuring a bulk multi-pass cell. This setup enables tunable Fourier-limited pulse durations as short as 42 fs. We examine th

Two Characteristic Contributions to the Superconducting State of 2H−NbSe2

Multiband superconductivity arises when multiple electronic bands contribute to the formation of the superconducting state, allowing distinct pairing interactions and gap structures. Here, we present field- and temperature-dependent data on the vortex lattice structure in 2H-NbSe2 as a contribution to the ongoing debate as to whether the defining feature of the superconductivity is the anisotropy

Biomaterials for in vitro models in lung research

In this chapter we introduce biomaterials science to a nonexpert reader in order to provide new perspectives for the development of in vitro three-dimensional models that are relevant in lung research. Specifically, we provide a comprehensive description of key concepts in the fields of biomaterials science and lung research to explain how merging them can give rise to new models of lung biology a

Diagnostic Dosimetry

Diagnostic nuclear medicine, more recently also named functional molecular imaging, deals with medical procedures performed to help diagnose a variety of diseases. The procedures are based on the use of tracer amounts of radioactive material, where a radionuclide is attached to a ligand with specific affinity to a physiological, metabolic, or receptor-specific process. To balance the benefit of a

Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects

Rapid-eye movement (REM) sleep behavior disorder (RBD), enactment of dreams during REM sleep, is an early clinical symptom of alpha-synucleinopathies and defines a more severe subtype. The genetic background of RBD and its underlying mechanisms are not well understood. Here, we perform a genome-wide association study of RBD, identifying five RBD risk loci near SNCA, GBA, TMEM175, INPP5F, and SCARB

Characterizing Ultrashort Laser Pulses With a Time-Dependent Polarization State Using the D-Scan Technique

The main idea behind the presented work is to extend the dispersion scan (d-scan) technique to measuring the time-dependent polarization state of ultrashort laser pulses. For demonstration, a rapidly varying polarization state, i.e. a polarization gate, was created from ultrashort pulses with a duration of 6 fs using a combination of wave plates. The time-dependent variation of the polarization wa

Is There Any Role for Opioids in the Management of Knee and Hip Osteoarthritis? A Systematic Review and Meta-Analysis

Objective: Opioids have long been prescribed for chronic pain conditions, including osteoarthritis (OA). However, there is little information about their temporal efficacy, or differences in efficacy and safety between opioids with strong versus weak/intermediate μ opioid receptor–binding affinity. To explore these research questions, we conducted a systematic review and meta-analyses of randomize

Short-term effect of induced alterations in testosterone levels on fasting plasma amino acid levels in healthy young men

Long term effect of testosterone (T) deficiency impairs metabolism and is associated with muscle degradation and metabolic disease. The association seems to have a bidirectional nature and is not well understood. The present study aims to investigate the early and unidirectional metabolic effect of induced T changes by measuring fasting amino acid (AA) levels in a human model, in which short-term

Inducible nitric oxide synthase expression is increased in the alveolar compartment of asthmatic patients

Introduction: Increased exhaled nitric oxide (NO) levels in asthma are suggested to be through inducible NO synthase (iNOS). The aim of this study was to investigate the expression of iNOS in bronchoalveolar lavage (BAL) cells and tissue from central and peripheral airways and compare it with the exhaled bronchial and alveolar NO levels in patients with asthma vs a control group. Methods: Thirty-t

Between the Highway and the Red Dirt Track : Subaltern Urbanization and Census Towns in India

In the 2011 census of India, more than 2500 settlements have been newly inducted into the category of ‘census towns’ – the lowest size-class of urban settlements in India. This is a staggering figure in light of the observation that a comparable number constituted the total number of all urban settlements recorded since 1900. Furthermore, it has been revealed through aerial images, that a vast maj

Doppler Audio Signal Analysis as an Additional Tool in Evaluation of Umbilical Artery Circulation

Purpose: To investigate the predictive capacity of a new method for sound spectrum analysis of Doppler signals recorded from the umbilical artery in high-risk pregnancies. Material and Methods: The retrospective study comprised 127 pregnant women with various pregnancy complications between 23 and 39 gestational weeks. Umbilical artery blood flow velocity waveforms were recorded with Doppler ultra

Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants

Background Diabetes has been defined on the basis of different biomarkers, including fasting plasma glucose (FPG), 2-h plasma glucose in an oral glucose tolerance test (2hOGTT), and HbA(1c). We assessed the effect of different diagnostic definitions on both the population prevalence of diabetes and the classification of previously undiagnosed individuals as having diabetes versus not having diabet

Effects of production and market factors on ethanol profitability for an integrated first and second generation ethanol plant using the whole sugarcane as feedstock

Background: Sugarcane is an attractive feedstock for ethanol production, especially if the lignocellulosic fraction can also be treated in second generation (2G) ethanol plants. However, the profitability of 2G ethanol is affected by the processing conditions, operating costs and market prices. This study focuses on the minimum ethanol selling price (MESP) and maximum profitability of ethanol prod

Associations of sex, anthropometric and reproductive factors with clinicopathological and molecular characteristics of colorectal cancer

Colorectal cancer (CRC) is the third most common cancer globally, with approximately 1.2 million new cases every year. The highest incidence rates are seen in developed countries, thereby imposing dietary and lifestyle factors in the etiology of CRC. Accumulating epidemiological evidence suggests that obesity is a risk factor for CRC in particular in men, as weak or no associations are seen in wom

The methods of historical reconstruction in the scholarly "recovery" of Corinthian Christianity

A somewhat self-critical discussion of the role played by socio-historical information (e.g. about money in social relations) in historical interpretation of ancient and early Christian history, and of the standpoints of Gerd Theissen, Justin Meggitt and Eckehard and Wolfgang Stegemann in this area. The article also explores the role of sociological or social-scientific models in historical recons