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As a result of an increasing number of bacteria developing resistance against antibiotics, antimicrobial peptides (AMPs) are attracting significant interest, particularly in relation to identification of peptides displaying potent but selective effects. Much less focus has been placed on delivery systems for AMPs, despite AMPs suffering from delivery challenges related to their size, cationicity,
Acquired angioedema due to C1-inhibitor (C1INH) deficiency (AAE) is caused by secondary C1INH deficiency leading to bradykinin-mediated angioedema episodes. AAE typically presents in adulthood and is associated with B cell lymphoproliferation. Anti-C1INH autoantibodies (antiC1INHAbs) are detectable in a subset of AAE cases and considered a hallmark of the disease. When free antiC1INHAbs and malign
A Kalman filter can be used to determine material parameters using uncertain experimental data. However, starting with inappropriate initial values for material parameters might cause false local attractors or even divergence. Also, inappropriate choices of covariance errors of the state and the measurements might affect the stability of the prediction. The present method suggests a simple way to
Att arbeta som kassör vid utgångskassa anses vara ergonomiskt belastande. En vanlig uppfattning är att om kunden lägger varorna en och en på bandet samt vänder EAN-koden mot scannern, så minskar kassörens arbetsbelastning.Arbets- och miljömedicin Syd har i samarbete med Handelsanställdas Förbund genomfört en pilotstudie i kassaarbete vid scanning av varor. Pilotstudiens syfte är att undersöka om d
Imaging through turbid environments is experimentally challenging due to multiple light scattering. Structured laser illumination has proven to be effective to minimize errors arising from this phenomenon, allowing the interior of optically dense media to be observed. However, in order to preserve the image spatial resolution while suppressing the intensity contribution from multiple light scatter
Geomorphological mapping is a well-established method for examining earth surface processes and landscape evolution in a range of environmental contexts. In glacial research, it provides crucial data for a wide range of process-oriented studies and palaeoglaciological reconstructions; in the latter case providing an essential geomorphological framework for establishing glacial chronologies. In rec
Background: Effective digestive enzymes are crucial for successful islet isolation. Supplemental proteases are essential because they synergize with collagenase for effective pancreatic digestion. The activity of these enzymes is critically dependent on the presence of Ca2+ ions at a concentration of 5–10 mM. The present study aimed to determine the Ca2+ concentration during human islet isolation
We present a study of optical signatures of salmon lice and the ability to distinguish them from a reference zooplankton species. This forms the basis for developing an instrument for detecting salmon lice in situ.
Indolecarboxamidotetrazole compounds are well known as potential anti allergic agents due to their mast cell stabilizing activity on human basophils. A quantitative structure activity relationship (QSAR) model has been generated using Multiple Linear regression (MLR) for the prediction of inhibition efficiency of indolecarboxamidotetrazole derivatives. Twenty-one compounds with their activities ex
Together with staff from home care from four municipalities we investigated how e-health services can improve the work environment. In a series of four workshops we coached the participants in (1) describing their work process and pinpointing the problematic situations in the process, (2) formulating their wishes for an ideal work process, (3) conceptualizing how e-health solutions can be used to
Here, we report a sol-gel integrated affinity microarray for on-chip matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), which enables capture and identification of prostate-specific antigen (PSA) in samples. Protein microarray technologies, which involve miniaturizing spots of capture agents (such as antibody and aptamers) on a solid surface, enable multia
Objective To compare PET imaging of tau pathology with CSF measurements (total tau [t-tau] and phosphorylated tau [p-tau]) in terms of diagnostic performance for Alzheimer disease (AD). Methods We compared t-tau and p-tau and 18 F-AV-1451 in 30 controls, 14 patients with prodromal AD, and 39 patients with Alzheimer dementia, recruited from the Swedish BioFINDER study. All patients with AD (prodrom
Bone tissue is commonly transplanted during orthopedic surgeries, primarily for the management of bone defects caused by trauma or various orthopedic conditions including, but not limited to, infections and tumours. Bone grafts are a surgeon’s choice, but their associated drawbacks are paving the way for biomaterial based bone graft substitutes. Biomaterials inherently lack the ability to induce s
Aiming at a feasible industrial scale bioplastic (PHAs) production, a microbial-based PHA-extraction technique was developed and investigated for extraction of different kinds of PHAs and a variety of well-studied producing microbial strains. This technology could make bioplastics production free of the use of organic solvents or other recovery chemicals. The technology allows the co-production of
