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In this study a set of structures has been simulated to represent a range of clinically relevant breast cancer mammographic lesions including solid tumours and microcalcifications. All structures have been created using simple random-based mathematical functions and have been inserted into a subset of digital mammography images at appropriate contrast levels into various regions of the breast, inc

Denna rapport behandlar manuella metoder för injustering av passiva, sidokopplade flödesnät med hjälp av differenstryckmätning. För ett normalt värmesystem i en byggnad innebär detta i klartext injustering av stamventiler men inte av radiatorventiler.

The sensitivity to geometrical imperfections of various test methods for wood-adhesive bonds was investigated using nonlinear finite element analysis. The adhesive layers in the specimens were modelled using a nonlinear softening, fracture mechanics model. The specimen types corresponded to the standards according to ASTM-D4680, ASTM-D905, EN-302-1 and a modified version of the ASTM-D3535 specimen

Photodynamic therapy (PDT) for the treatment of prostate cancer has been demonstrated to be a safe treatment option capable of inducing tissue destruction and decreasing prostate specific antigen (PSA) levels. However, prostate-PDT results in large intra- and interpatient variations in treatment response, possibly due to biological variations in tissue composition and short-term response to the th

The majority of microarray studies focus on analysis of gene expression differences between various specimens or conditions. However, the causes of this variability from one cancer to another, from one sample to another and from one gene to another often remain unknown. In this study, we present a systematic procedure for finding genes whose expression levels are altered due to an intrinsic or ext

Purpose: Supply chain efficiency (economic and ecological) is affected by packaging design. The purpose of this research is to investigate how integrated approaches aiming for ecoefficient supply chains are used in packaging development processes and how a set of preselected factors influences the adaption of more or less integrated approaches at companies. Design/methodology/approach: The researc

This report is produced within the Urban Transition Øresund (UT) project (2011–2014), and it is part of the subtask Collaborative Methods and Tools for Urban Transitions (UT CoMeT). The goal of the UT project is to promote sustainable growth and advance sustainable urban transformation in the Øresund region by gathering municipalities, universities and businesses in cross-border cooperation. The s

During the last decade, a rapid progress has been made in the development of validated analytical models for the thermal and mechanica1 behaviour of fire exposed structures and structural members. In a long-term perspective, the development now goes towards an analytical design, directly based on a natural fire exposure and specified with respect to the combustion characteristics of the fire load

Popular Abstract in Swedish Wnt-5a-genens betydelse för bröstcellernas normala funktion och för uppkomsten av bröstcancer I min avhandling har jag studerat en i bröstcancersammanhang hittills föga undersökt gen, Wnt-5a. Benämningen Wnt har bildats genom en sammanslagning av "Wingless" (den första identifierade Wnt-genen som orsakar vinglöshet hos bananflugan) och "Int" (från "Integration site" föThe Wnt-5a gene encodes a secreted protein that regulates several normal processes in embryonic and adult tissues by as yet unknown mechanisms. Expression of Wnt-5a protein does not cause cell transformation, but it instead counteracts the effects induced by transforming Wnts. Inasmuch as Wnt-5a can activate the Wnt/beta-catenin signalling pathway, we performed experiments to determine whether mol

Popular Abstract in Swedish Det huvudsakliga syftet med den presenterade forskningen var att bygga en förståelse för hur dynamiken mellan professioner, verktyg och objekt fungerar på en operationsavdelning, som ett led i framtagandet av kunskap användbar vid design av framtidens operationsavdelning med fokus på arbetsmiljö, effektivitet och patient säkerhet. Igenom att undersöka hur olika professiThe main objective of the research presented was to gain an understanding of how the dynamics between professionals, tools and objectives work in an operating unit in order to obtain knowledge useful when designing the operating unit of the future with emphasis on the work environment, effectiveness and patient safety. By investigating how different professions in the operating theatre view their

The design of a digital baseband for a low power wireless receiver in 65 nm CMOS is presented. It consists of decimation filtering, matched filters for data detection, and preamble based synchronization. The circuit was designed using low threshold devices in both low power (LP-LVT) and general-purpose (GP-LVT) domains. The fabricated circuits were functionally verified, and silicon measurements s