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Co-simulation is widely used in industry for the simulation of multi-domain linear-time-invariant systems. However, as a result of the not continuous communication between our coupling variables, simulation results end up being unstable and inaccurate. Among the different strategies that have been developed in the recent years to control co-simulation drawbacks, the aim of this thesis is to unders
Introduction: Gas chromatography-mass spectrometry (GC-MS) is a powerful tool when used in metabolomics, the study of small molecules in the body, and investigating new modes of using it might lead to even better tools for diagnostics and research. Background: Chemical ionization (CI) for GC-tandem MS (GC-MS/MS) is relatively rarely used compared to the more commonplace electron ionization (EI).
This thesis examines the theory of headwinds by Robert J Gordon related to Sweden’s economic growth since the 1970s. The specific questions asked are how the two headwinds of income inequality and educational attainment in the USA can be related to a Swedish context. Gordon’s theory is part of a debate on secular stagnation. This thesis aims to broaden that debate by applying one theory of secular
Purpose/Background: Utilizing proton therapy (PT) for treatment of Hodgkin’s lymphoma (HL) has demonstrated favorable features, particularly a reduced dose to organs at risk (OAR) in comparison with photon radiotherapy. However, there is a coherent complexity with PT including its uncertainties, such as range-uncertainties and set-up variations as protons are highly sensitive to tissue density var
Om en part har tillräckligt starka misstankar om att motparten inte kommer att fullfölja sina avtalsförpliktelser och begå ett avtalsbrott vill den drabbade parten naturligtvis skydda sig från att drabbas av brottet. Den drabbade parten kan skydda sig mot ett s.k. befarat avtalsbrott genom att utöva stoppningsrätten eller hävningsrätten. Stoppningsrätten regleras i 61 § KöpL och innebär att den drIf a party suspects the other party will not fulfill a substantial part of his obligations according to the contract this would mean that they are breaching the terms of their contract. This means that the affected party can protect itself against a breach of contract, “anticipatory breach”, under contractual law by exercising the rights of suspension or cancellation (stoppningsrätten or hävningsr
Titel: Validering av en handledsburen aktivitetsmätare och en självskattningskala för beräkning av VO2max. Bakgrund: Fysisk aktivitet och god aerob kapacitet är kopplat till god hälsa och lägre risk för livsstilsrelaterade sjukdomar. I dagsläget anses maximalt arbetsprov med ergospirometri och gasanalys för bestämning av VO2max (VO2max-test) vara det mest exakta sättet att mäta aerob kapacitet. Su
Kubernetes is a container orchestration platform growing ever more popular, and as the software industry shifts into the container cloud, security will become paramount. The Common Vulnerabilities and Exposures (CVEs) systems cata- log and provide references to known vulnerabilities. The goal of this thesis is to systematically evaluate the security situation of Kubernetes through common mitigatio
In this project, I investigate the combination of Natural Language Processing (NLP) with Item Response Theory (IRT) to advance the assessment and scoring of open response items. Traditional psychometric assessments are grounded in well-defined quality standards, yet assessments based on natural language have missed meeting these standards. To address this gap, I integrate NLP processed open respon
Monte Carlo simulation is a numerical method that can simulate complex physical systems and is widely used in the field of medical optics. For example, the Monte Carlo method was used to evaluate the effectiveness of near-infrared spectroscopy (NIRS) in the detection of intracranial hematoma (ICH). However, due to the relatively complex brain structure, the current simulation model is relatively s
This section gives an overview of Lake Victoria, that is currently underutilized for cargo transportation by the 3 East African states of Uganda, Kenya and Tanzania, despite the great potential of this shared water body for multimodal transport and trade opportunities. In order to sustainably develop infrastructure on Lake Victoria, the three member states must adopt sustainable business models t
Spatial transcriptomics, a powerful technique that merges sequencing and spatial data, offers unprecedented resolution for studying gene expression within tissues. This study focuses on developing a pipeline to design probes for Multiplexed Error-Robust Fluorescence In Situ Hybridisation (MERFISH) experiments to investigate the spatial distribution of the lung microbiome. Metagenomic data analysis
Automation and robotics have been widely integrated across various industries, yet the building sector has not seen significant evolution over the last few centuries. This thesis presents a concept for integrating automation at construction sites, specifically for the assembly of wooden prefabricated walls. When working with wooden prefabricated house elements the sizes are typically large, 6-10 m
Today aromatic ring flipping has become a classic example to highlight the highly dynamic character of proteins. These dynamics occur when the aromatic side chains in phenylalanine and tyrosine turn 180o around its Cβ–Cγ axis, also known as its χ2 dihedral. Discovered in the 1970s’ these ring flippings are a common internal probe used in NMR spectroscopy to understand the protein interior dynamics
The two most recent parliamentary elections in Sweden were followed by intense negotiation and remarkable long periods of time before government formation. This culminated in comprehensive agreements between the government parties and supporting parties. The January Agreement was the foundation for Stefan Löfven’s government (Januariavtalet, 2019), and the Tidö Agreement is the foundation for Ulf
HP-hjälpen var ett företag som erbjöd sina kunder en tjänst som hjälpte dem att fuska på högskoleprovet. HFD har meddelat prövningstillstånd för ett mål gällande huruvida denna olagliga tjänst ska mervärdesbeskattas. En liknande fråga avgjordes i NJA 2021 s. 99, och frågan har ett flertal gånger avgjorts av EUD. Denna uppsats utgår ifrån rättsdogmatisk och EU-rättslig metod, och undersöker hur EUDHP-hjälpen was a company that offered their customers an illegal service that helped them to cheat on the Swedish Scholastic Aptitude Test. The Swedish Supreme Administrative Court granted leave to appeal in a case about whether this illegal service should be subject to VAT. A similar question was ruled on in NJA 2021 p. 99, and the question had been subject to several previous rulings by the CJEU
Electric vehicles are becoming more common as one of many solutions to the increasingly serious problem of global warming. This comes with new safety challenges as batteries can upon malfunction or abuse enter thermal runaway and as a result catch fire or explode. The gases released from thermal runaway has been determined experimentally in published studies and have been shown to contain fluorina
Membrane proteins are important building blocks for several biochemical processes. The difficulty with membrane proteins is that they tend to be lowly expressed and can be difficult to manage. Therefore, membrane proteins are studied to a lesser extent than soluble proteins. Since membrane proteins are intrinsically hydrophobic, their purification and structural determination critically rely on so
