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Circulating Growth Differentiation Factor 15 Levels Are Associated With Risk of Both Intracerebral and Subarachnoid Hemorrhage

Background: Growth differentiation factor 15 (GDF-15) has been associated with the risk of developing major bleedings, including but not restricted to intracranial hemorrhages, in patients on oral anticoagulants or dual antiplatelet therapy. We hypothesized that there may be an association of GDF-15 with incidence of hemorrhagic strokes in the general population, which has not been investigated be

Revisiting socio-economic inequalities in sedentary leisure time in Sweden: An intersectional analysis of individual heterogeneity and discriminatory accuracy (AIHDA)

Aims:Swedish public health reports have repeatedly provided information about socio-economic inequalities in sedentary leisure time, despite that, in the interest of health equity, physical activity should be equally distributed in the population. Such public health reports, however, neither consider the intersection of multiple socio-demographic factors nor the individual heterogeneity around gro

Oxidation of a Platinum-Tin Alloy Surface during Catalytic CO Oxidation

We have investigated the surface composition of a well-ordered Pt3Sn(111) surface during CO oxidation with ambient pressure X-ray photoemission spectroscopy. Oxidation of tin in the surface coincides with the onset of catalytic conversion, and we observe significant differences in the oxidation state and morphology of the oxide formed depending on the gas composition, with an oxygen-rich mixture l

Health locus of control and all-cause, cardiovascular, cancer and other cause mortality : A population-based prospective cohort study in southern Sweden

The aim was to investigate associations between health locus of control (HLC) and all-cause, cardiovascular (CVD), cancer and other cause mortality. A public health postal questionnaire was distributed in the autumn of 2008 to a stratified random sample of the 18–80 year old adult population in Scania in southernmost Sweden. The participation rate was 54.1%, and 25,517 participants were included i

Extreme variation in recombination rate and genetic diversity along the Sylvioidea neo-sex chromosome

Recombination strongly impacts sequence evolution by affecting the extent of linkage and the efficiency of selection. Here, we study recombination over the Z chromosome in great reed warblers (Acrocephalus arundinaceus) using pedigree-based linkage mapping. This species has extended Z and W chromosomes (“neo-sex chromosomes”) formed by a fusion between a part of chromosome 4A and the ancestral sex

Effects of Infant Massage : A Systematic Review

Infant massage is performed in various international contexts. There is a need for an updated literature review on this topic. The purpose of the current review was to investigate the effects of infant massage. A systematic literature review was conducted to investigate the effects of infant massage on the following outcomes: pain relief, jaundice, and weight gain. The inclusion criteria were infa

HIV self-testing for men who have sex with men in Sweden. A cross-sectional study concerning interest to use HIV self-tests

Background: HIV self-testing (HIVST) has been found to have high acceptability among men who have sex with men (MSM) internationally and might contribute to increase testing frequencies, but many countries, including Sweden, lack policies for using HIVST. Objective: To examine interest to use and willingness to pay for HIVST, and associated factors, among MSM attending HIV testing venues in Sweden

Water Chemistry beneath Graphene : Condensation of a Dense OH-H2O Phase under Graphene

Room temperature oxygen hydrogenation below graphene flakes supported by Ir(111) is investigated through a combination of X-ray photoelectron spectroscopy, scanning tunneling microscopy, and density functional theory calculations using an evolutionary search algorithm. We demonstrate how the graphene cover and its doping level can be used to trap and characterize dense mixed O-OH-H2O phases that o

Performance, Analysis, and Modeling of III-V Vertical Nanowire MOSFETs on Si at Higher Voltages

Heterostructure engineering in III-V vertical nanowire (VNW) MOSFETs enables tuning of transconductance and breakdown voltage. In this work, an InxGa 1−x As channel with a Ga-composition grading ( x= 1–0.4) in the channel and drain region, combined with field plate engineering, enables breakdown voltage above 2.5 V, while maintaining transconductance of about 1 mS/ μm , in VNW MOSFETs. The field p

The association between serum estradiol levels and sperm DNA integrity

In men from the general population, BMI has been associated with a lower sperm DNA fragmentation index (DFI). We wondered whether this could be due to estradiol, which is associated with BMI and reported important for sperm function. Our objective was to investigate the association between estradiol and DFI. In 2008–2010, we recruited 284 young men from the general population to deliver samples of

LEVELS OF IL-6 AND OTHER INFLAMMATORY PROTEINS IN EARLY RA PREDICT JOINT DAMAGE PROGRESSION OVER 5 YEARS

Background Joint damage in rheumatoid arthritis (RA) remains a significant problem. Identification of biomarkers associated with joint destruction can improve our understanding of underlying disease processes and future management.Objectives To evaluate inflammatory proteins as potential predictors of radiographic progression of joint damage.Methods Consecutive early RA patients (symptom duration

PREDICTORS OF EROSION AND JOINT SPACE NARROWING PROGRESSION IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS

Background: Joint damage in rheumatoid arthritis (RA) includes erosions and joint space narrowing (JSN). Predictors of these processes, and the underlying mechanisms, require further study1.Objectives: To investigate the relation between patient characteristics at RA diagnosis and progression of erosions and JSN, over 5 years. Methods: Consecutive early RA patients (symptom duration Results: 233 e

Enhancement of phase change materials by nanoparticles to improve battery thermal management for autonomous underwater vehicles

Battery thermal management (BTM) plays a significant role in the safety and reliability of autonomous underwater vehicles (AUV) at higher speeds. In this study, a nanoparticle/phase change material (nano-PCM) composite is proposed for the BTM of an AUV. The effects of nanoparticle loading percentage (φ = 5, 10, and 15%) and nanoparticle filling range (α = 30, 60, 90, and 120°) on the battery tempe

Performance improvement of proton exchange membrane fuel cells with wavy flow channels : An experimental study

The gas flow field design plays a vital role in the cell performance of proton exchange membrane fuel cells, especially at high current densities. In this study, wavy flow channels are designed and adopted on the cathode side to enhance the mass transport process. Results demonstrate that the wavy flow channels proposed in this paper significantly improve cell performance at high current densities

Remission and low disease activity (LDA) prevent damage accrual in patients with systemic lupus erythematosus : Results from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort

Objective: To determine the independent impact of different definitions of remission and low disease activity (LDA) on damage accrual. Methods: Patients with ≥2 annual assessments from a longitudinal multinational inception lupus cohort were studied. Five mutually exclusive disease activity states were defined: remission off-treatment: clinical Systemic Lupus Erythematosus Disease Activity Index (

Fluid flow and heat transfer in a rectangular ribbed channel with a hierarchical design for turbine blade internal cooling

For internal cooling of a turbine blade, various advanced rib turbulators can markedly contribute to the heat transfer enhancement while suffering a great increase in pressure loss. In those designs, ribs with the same configuration are periodically and evenly mounted on the channel wall. In this context, this work proposes a hierarchical design concept to optimize the rib arrangement with the des