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Sintering of BN Based Composites with ZrC and Al under High Temperatures and Pressures

Abstract: The sintering of cubic boron nitride (cBN) based ceramic matrix materials with zirconium carbide and aluminum has been carried out under high pressures and temperatures. The performed study has revealed that the interaction between mixture components with the formation of a new phase, namely, zirconium diboride (ZrB2) occurs at sintering temperatures above 1750°C and an applied pressure

The power of empirical data; lessons from the clinical registry initiatives in Scandinavian cancer care

Background: In Scandinavia, there is a strong tradition for research and quality monitoring based on registry data. In Denmark, Norway and Sweden, 63 clinical registries collect data on disease characteristics, treatment and outcome of various cancer diagnoses and groups based on process-related and outcome-related variables. Aim: We describe the cancer-related clinical registries, compare organiz

Comparative effectiveness of abatacept, rituximab, tocilizumab and TNFi biologics in RA : Results from the nationwide Swedish register

Objectives: Current guidelines rank abatacept, rituximab, tocilizumab and TNF-inhibitors (TNFi) as having equal effectiveness for the treatment of RA, at least as second line therapies. These recommendations are mainly based on meta-analysis of randomized controlled trials, with few direct drug-drug comparisons. Our objective was to compare the real-world absolute and relative effectiveness among

Ultrafast Optical Generation of Coherent Bright and Dark Surface Phonon Polaritons in Nanowires

The subwavelength confinement and enhanced electric field created by plasmons allow precise sensing and enhanced light–matter interaction. However, the high frequency and short lifetime of plasmons limit the full potential of this technology. It is crucial to find substitutes and to study their dynamics. Here, we propose an experimental approach allowing the time-domain study of surface phonon pol

Spin-orbit-resolved spectral phase measurements around a Fano resonance

We apply a spectrally-resolved electron interferometry technique to the measurement of the spectral phase in the vicinity of the 3s13p64p Fano resonance of argon. We show that it allows disentangling the phases of the two nearly-overlapping electron wavepackets corresponding to different spin-orbit final states. Using simple assumptions, it is possible to process the experimental data and numerica

Molecular structure of maltoside surfactants controls micelle formation and rheological behavior

Hypothesis: The anomeric configuration (α or β) of n-hexadecyl-D-maltopyranoside (C16G2) has been shown to affect the morphology of the micelle, from elongated for α-C16G2 to worm-like micelles for β-C16G2. The entanglement of worm-like micelles often leads to strong modifications of the rheological behavior of the system and, as such, the anomeric configuration of C16G2 could also provide the pos

Incidence and prevalence of giant cell arteritis and polymyalgia rheumatica : A systematic literature review

Background: Giant cell arteritis (GCA; sometimes referred to as temporal arteritis) and polymyalgia rheumatica (PMR) are common and interrelated inflammatory conditions that almost exclusively affect adults older than 50 years. There is a need for updated information on the epidemiology of these diseases. Objective: This systematic literature review (SLR) aims to summarize current evidence regardi

Spoken Language and Language Impairment in Deaf and Hard-of-Hearing Children: Fostering Classroom Environments for Mainstreamed Children

Despite medical, technical, and pedagogical advances, the risk for language impairment is still much higher in deaf and hard-of-hearing (DHH) children than in hearing peers. Research on linguistic, cognitive, and communicative development in DHH children has found a range of basic spoken language deficits. Twenty percent to 50% of deaf children still meet criteria for language impairment. Tests of

Effect of Radius on Crystal Structure Selection in III-V Nanowire Growth

The radius of III-V nanowires is known to have an effect on the resulting crystal structure during particle-assisted growth; however, the causes behind this effect remain under debate. In this work, we use stochastic simulations of nanowire growth to evaluate how the radius (R) affects the growth dynamics and how this in turn affects the crystal structure selection. This is due to the geometry of

A Cross-Sectional Cohort Study of Extended-Spectrum-Beta-Lactamase-Producing Enterobacterales in Patients with Traveler's Diarrhea

Patients with traveler’s diarrhea (TD) can acquire extended-spectrum-beta-lactamase (ESBL)-producing members of the Enterobacterales (EPE) during travel to areas of endemicity. The aim of the present study was to investigate the prevalence and characteristics of EPE carriage in travelers from southern Sweden who were sampled for bacterial diagnostics of TD compared to those of EPE carriage 10 year

Education, immigration and rising mental health inequality in Sweden

Educational and income gradients in health are well established in the literature but there is need for a better understanding of how mental health inequalities change over time, and what drives the development. We aim to study how psychiatric diagnosis and its income-related inequality have changed over time in Sweden and to make a first attempt at disentangling the development by decomposing any

Diverging responses to threats across generations in zooplankton

Our understanding on how organisms evolutionarily cope with simultaneously occurring, multiple threats over generations is still elusive. In a long-term experimental study, we therefore exposed clones of a freshwater cladoceran, Daphnia magna, to threats from predation and ultraviolet radiation (UVR) during three consecutive parthenogenetic generations. We show that Daphnia can adapt to different

Heterogeneity in the associations between common mental disorders and labour outcomes - a population study from southern Sweden

BACKGROUND: Previous research has shown that Common Mental Disorders (CMD) are unequally distributed between population subgroups, but we know less about how labour outcomes following such disorders are distributed. Our aim is to investigate how the labour outcomes following a CMD diagnosis differ over sex, age, schooling and country of birth.METHODS: We use a population sample from southern Swede

Surface rheology and morphology of beer protein and iso-humulone at air-liquid surface

Foam is one of the unique properties of beer, but how the amphiphilic components stabilize the foam is still not fully understood. This study concerns the main surface active components. For this purpose, protein from barley and iso-humulone from hop, were extracted from raw materials separately to be able to consider their effect separately and in the controlled mixture. The layers were formed in

SMIM1, carrier of the Vel blood group, is a tail-anchored transmembrane protein and readily forms homodimers in a cell-free system

Antibodies to the Vel blood group antigen can cause adverse hemolytic reactions unless Vel-negative blood units are transfused. Since the genetic background of Vel-negativity was discovered in 2013, DNA-based typing of the 17-bp deletion causing the phenotype has facilitated identification of Vel-negative blood donors. SMIM1, the gene underlying Vel, encodes a 78-amino acid erythroid transmembrane

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

Breast cancer susceptibility variants frequently show heterogeneity in associations by tumor subtype1-3. To identify novel loci, we performed a genome-wide association study including 133,384 breast cancer cases and 113,789 controls, plus 18,908 BRCA1 mutation carriers (9,414 with breast cancer) of European ancestry, using both standard and novel methodologies that account for underlying tumor het

Exploring the light-induced dynamics in solvated metallogrid complexes with femtosecond pulses across the electromagnetic spectrum

Oligonuclear complexes of d4-d7 transition metal ion centers that undergo spin-switching have long been developed for their practical role in molecular electronics. Recently, they also have appeared as promising photochemical reactants demonstrating improved stability. However, the lack of knowledge about their photophysical properties in the solution phase compared to mononuclear complexes is cur

Electron channelling : challenges and opportunities for compositional analysis of nanowires by TEM

Energy dispersive x-ray spectroscopy in a transmission electron microscope is often the first method employed to characterize the composition of nanowires. Ideally, it should be accurate and sensitive down to fractions of an atomic percent, and quantification results are often reported as such. However, one can often get substantial errors in accuracy even though the precision is high: for nanowir