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The effect of a biphasic injectable bone substitute on the interface strength in a rabbit knee prosthesis model.

In joint prosthetic surgery, various methods are used to provide implant stability. We used an injectable bone substitute, composed of calcium sulfate/hydroxyapatite, as bone defect filler to stabilize a tibia prosthesis in an experimental rabbit model. The aim of the study was to investigate and compare the stability of prosthetic fixation with and without the use of an injectable bone substitute

Sandwiched confinement of quantum dots in graphene matrix for efficient electron transfer and photocurrent production.

Quantum dots (QDs) and graphene are both promising materials for the development of new-generation optoelectronic devices. Towards this end, synergic assembly of these two building blocks is a key step but remains a challenge. Here, we show a one-step strategy for organizing QDs in a graphene matrix via interfacial self-assembly, leading to the formation of sandwiched hybrid QD-graphene nanofilms.

Balancing Electron Transfer and Surface Passivation in Gradient CdSe/ZnS Core-Shell Quantum Dots Attached to ZnO

Core-shell (CS) quantum dots (QDs) are promising light absorbers for solar cell applications mainly because of their enhanced photostability compared with bare QDs. Moreover, the superb photostability can be combined with a low number of defects by using CSQDs with a gradient composition change from the core to the shell. Here, we study electron injection from the gradient CSQDs to ZnO nanoparticl

Climate Change, Adaptation, and Formal Education: the Role of Schooling for Increasing Societies' Adaptive Capacities in El Salvador and Brazil

With a worldwide increase in disasters, the effects of climate change are already being felt, and it is the urban poor in developing countries who are most at risk. There is an urgent need to better understand the factors that determine people's capacity to cope with and adapt to adverse climate conditions. This paper examines the influence of formal education in determining the adaptive capacity

Bulk-like transverse electron mobility in an array of heavily n-doped InP nanowires probed by terahertz spectroscopy

Terahertz spectroscopy is employed for the noncontact measurement of transversal mobility in InP nanowires, wherein photonic effects (waveguiding of excitation beam and propagation of terahertz beam in a complex gradient environment) were successfully deconvoluted. Monte Carlo calculations accounting for electron localization and heavy doping were used to determine electron momentum relaxation tim

Merging electronics and the brain - towards a fully biocompatible neural interface

Techniques for interfacing the nervous system using chronically implanted electrodes are turning into invaluable tools for neurophysiological research and treatment of neurological disorders. These methods have been developed and refined over the last decades. However, they still suffer from deteriorating electrical capabilities and the fact that they inevitably damage the tissue into which they a

Supercurrent and Multiple Andreev Reflections in an InSb Nanowire Josephson Junction

Epitaxially grown, high quality semiconductor InSb nanowires are emerging material systems for the development of high performance nanoelectronics and quantum information processing and communication devices and for the studies of new physical phenomena in solid state systems. Here, we report on measurements of a superconductor-normal conductor-superconductor junction device fabricated from an InS

Eating problems and overlap with ADHD and autism spectrum disorders in a nationwide twin study of 9- and 12-year-old children.

Aim. To establish the prevalence of restrictive eating problems, the overlap and association with attention-deficit/hyperactivity disorder (ADHD), and autism spectrum disorders (ASD) and to estimate the heritability of eating problems in a general population sample of twins aged 9 and 12. Methods. Parents of all Swedish 9- and 12-year-old twin pairs born between 1993 and 1998 (n = 12,366) were int

Breast cancer risk in women who fulfill high-risk criteria: at what age should surveillance start?

Family history is a strong predictor of hereditary breast cancer, particularly when it includes cases of early onset or bilateral breast cancers and multiple cases of breast or ovarian cancers. This article provides relative risks and cumulative risks of breast cancer in women whose family history indicates high risk. Specifically, the aim was to determine how many years earlier the high-risk wome

Novel approaches to explore mechanisms of epileptic seizures - optogenetic and chemogenetic manipulation of hippocampal circuitry

Epilepsy comprises a family of neurological disorders characterized by recurrent seizures, which can be highly debilitating. Up to 30% of patients with temporal lobe epilepsy, the most common form of the disorder in adults, arising in the hippocampus, cannot be effectively treated by current pharmaceuticals. Novel treatment strategies are highly needed, as well as increased understanding of the hi

Predictors of Presenteeism and Activity Impairment Outside Work in Patients with Spondyloarthritis

Purposes To assess predictors of presenteeism (reduced productivity at work) and activity impairment outside work in patients with spondyloarthritis (SpA). Methods Multivariate logistic regression analysis was used to study predictors of presenteeism and activity impairment in 1,253 patients with SpA based on a 2.5 year follow-up questionnaire. The Work Productivity and Activity Impairment (WPAI)

Anterior Cruciate Ligament injury, Patient Variables, Outcomes and Knee Osteoarthritis

The ruptured anterior cruciate ligament (ACL) leads to immediate symptoms that severely affect the individual and receives great attention among the scientific community, yet there is still no consensus on the optional form of treatment. An ACL injury is also a well known high risk factor for the development of knee osteoarthritis (OA) some decades later. Knee OA development after an ACL injury is

Oncostatin M acting via OSMR, augments the actions of IL-1 and TNF in synovial fibroblasts

OBJECTIVE: To identify how the gp130-signaling cytokine oncostatin M (OSM), acting alone or in concert with IL-1beta or TNFalpha, affects synovial fibroblast expression of genes relevant to inflammation and bone erosion in inflammatory arthritis. METHODS: Synovial fibroblasts (SFs) were isolated from non-arthritic wild type (WT) or OSM receptor deficient (OSMR(-/-)) mice and stimulated with OSM, I

Vehicle-vehicle Interactions at Roundabouts and their Implications for the Entry Capacity - A Methodological Study with Applications to Two-lane Roundabouts

Popular Abstract in Swedish Avhandlingen behandlar kapacitet i cirkulationsplatser. Kapaciteten för ett körfält i en tillfart kan beräknas med teorin för kritiska tidsavstånd. Denna bygger på interaktioner mellan fordon med företräde (överordnade fordon) och fordon som skall lämna företräde (underordnade fordon). Det kritiska tidsavståndet är det minsta tidsavstånd mellan två överordnade fordon soProblem: The thesis deals with the capacity of two-lane roundabouts and with vehicle-vehicle interactions there. Method: The interactions and the corresponding capacity are modelled by gap-acceptance theory. Various components of this theory are discussed, models for headways in the multi-lane case and for the estimation of critical gaps for the two major streams being developed and being applied

Epidemiological studies of severe infections in COPD

It is well known that patients with COPD have an increased risk of lower respiratory tract infections, but less is known about the association with other infections. The aim of this thesis was to explore epidemiological aspects of severe infections in COPD, using public registries in Sweden. In the first study, incidence rates of tuberculosis were compared in all individuals discharged with COPD,

Early exposure to secondhand tobacco smoke and the development of allergic diseases in 4 year old children in Malmo, Sweden

Background: Earlier studies have shown an association between secondhand tobacco smoke and allergy development in children. Furthermore, there is an increased risk of developing an allergy if the parents have an allergy. However, there are only few studies investigating the potential synergistic effect of secondhand tobacco smoke and allergic heredity on the development of an allergy. Methods: The

Mutual enhancement of the current density and the coulombic efficiency for a bioanode by entrapping bi-enzymes with Os-complex modified electrodeposition paints

A bioanode with high current density and coulombic efficiency was developed by co-immobilization of pyranose dehydrogenase from Agaricus meleagris (AmPDH) with the dehydrogenase domain of cellobiose dehydrogenase from Corynascus thermophiles (recDHCtCDH) expressed recombinantly in Escherichia coli. The two enzymes were entrapped in Os-complex modified electrodeposition polymers (Os-EDPs) with spec

Effects of an isocaloric healthy Nordic diet on insulin sensitivity, lipid profile and inflammation markers in metabolic syndrome - a randomized study (SYSDIET)

Background Different healthy food patterns may modify cardiometabolic risk. We investigated the effects of an isocaloric healthy Nordic diet on insulin sensitivity, lipid profile, blood pressure and inflammatory markers in people with metabolic syndrome. Methods We conducted a randomized dietary study lasting for 18-24weeks in individuals with features of metabolic syndrome (mean age 55years, BMI