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Popular Abstract in Swedish Målet med arbetet var att öka mängden vindkraft, solel och annan distribuerad generering (DG) som kan anslutas till befintliga distributionsnät på ett snabbt och kostnadseffektivt sätt. Att införa aktiv spänningsreglering i nätet, istället för installation av nya ledningar, har identifierats som en lämplig strategi. Då denna princip bygger på att DG-enheternas produktioDistributed generation (DG), i.e. generation connected to the low and medium voltage distribution network (DN), has been increasing a lot during recent years. Thus the traditional assumption of a unidirectional power flow and a voltage decrease along the distribution feeders is no longer valid in all operation conditions. Voltage control in these networks is often limited to the on-load tap change

PURPOSE: Several studies have indicated that broad genomic characterization of childhood cancer provides diagnostically and/or therapeutically relevant information in selected high-risk cases. However, the extent to which such characterization offers clinically actionable data in a prospective broadly inclusive setting remains largely unexplored.METHODS: We implemented prospective whole-genome seq

Introduction: Extractability of shea oil depends on its solubility and so the feasibility of upscaling the extraction method for industrial purposes can be understood by studying sample solubility. Background: Supercritical fluid extraction (SFE) is a greener technique than the current hexane extraction method but has not been utilized in shea oil yet and its solubility in supercritical carbon d

Background: Adult-onset diabetes comprises subgroups differing in pathophysiology, clinical presentation, and risk of comorbidities. We investigated early phenotypic differences between individuals who later developed diabetes, stratified by subgroup at diabetes diagnosis. Methods: We conducted a pooled analysis of nine prospective European cohorts with 3309 individuals developing incident diabete

Background and Purpose Post-mastectomy radiotherapy (PMRT) improves both the locoregional control and survival in advanced breast cancer. While the use of bolus can enhance skin dose, many oncologists prefer not to use it because of the dramatic increase in skin toxicity. The optimal technique to ensure adequate skin dose is unknown, and this study compares the superficial dose for three technique

Wei G, Bergquist A, Broome U, Lindgren S, Wallerstedt S, Almer S, Sangfelt P, Danielsson A, Sandber-Gertzen H, Loof L, Prytz H, Bjomsson E (Sahlgrenska University Hospital, Gothenburg; Karolinska University Hospital, Huddinge, Stockholm; University Hospital MAS, Malmo; University Hospital, Linkoping; University Hospital, Uppsala; University Hospital, Umea; University Hospital, Orebro; Central Hosp

During the Swedish NATO negotiations, the Turkish president Recep Tayyip Erdoğan once again raised the question of whether Türkiye could be welcomed into the EU. This thesis examines Türkiye’s shortcomings concerning their EU accession, focusing on the human rights of Kurdish people by answering the research questions: what is the state of human rights of the Kurd-ish people in Türkiye, and what c

Today's handheld computing devices equipped with novel wireless network technologies can provide their users with features such as mobility, multimedia support and group communication. On the other hand, the administrative effort required to enable all these features increases beyond the level that an ordinary user can manage. Ad hoc networks, being able to quickly organise themselves without user

Popular Abstract in Swedish Blodbildande stamceller förekommer i mänsklig benmärg i en frekvens på ca 1/100 000 celler. Med hjälp av cellytemarkörer, t.ex. CD34, kan man rena fram cellpopulationer som är anrikade på stamceller, men det saknas exakt kunskap om hur enskilda stamceller ser ut. De blodbildande stamcellerna har förmåga att vid celldelning antingen förnya sig själva eller att mogna ut. Hematopoietic stem cells (HSCs) have the capacity to maintain hematopoiesis throughout life. HSCs are ideal targets for permanent gene transfer, as the transgene will be expressed in all the progeny of the gene-modified stem cells. The aim of this thesis was to optimize conditions for retroviral gene transfer to human candidate HSCs and to study mechanisms interfering with efficient gene transfer.

Popular Abstract in Swedish Miljontals fåglar lämnar Sverige varje höst för att övervintra på sydligare breddgrader och återvänder nästkommande vår för att föda upp sina ungar på de enorma mängder insekter som finns här tack vare det tempererade klimatet. Småfåglar genomför sin flytt etappvis genom att flyga ett antal dagar eller nätter i sträck, beroende på om fågeln är en dag- eller nattsträckarSongbird migrants use stopovers between flight bouts to rest and refuel for the upcoming flights. Behaviours affecting where, when and how long to stay at stopover sites will affect how successful the overall migration will be, which has significant consequences for the overall fitness and mortality of the birds. The main purpose of this work was to investigate stopover behaviours in free-flying m

OBJECTIVE: To identify perinatal factors associated with cerebral palsy (CP). METHODS: This was a case-control study based on the Swedish Medical Birth Registry and the Swedish Hospital Discharge Registry, including 2,303 infants born in Sweden 1984-1998 with a diagnosis of CP and 1.6 million infants without this diagnosis. Odds ratios (ORs) with 95% confidence intervals (Cis) were calculated. RES

Polycomb repressive complex 2 (PRC2) and its core member enhancer of zeste homolog 2 (EZH2) mediate the epigenetic gene silencing mark: trimethylation of lysine 27 on histone 3 (H3K27me3). H3K27me3 is characteristic of the chromatin at genes involved in developmental regulation in undifferentiated cells. Overexpression of EZH2 has been found in several cancer types such as breast, prostate, melano

Purpose EURAMOS-1, an international randomized controlled trial, investigated maintenance therapy with pegylated interferon alfa-2b (IFN-α-2b) in patients whose osteosarcoma showed good histologic response (good response) to induction chemotherapy. Patients and Methods At diagnosis, patients age ≤ 40 years with resectable high-grade osteosarcoma were registered. Eligibility after surgery for good

Weight-loss interventions generally improve lipid profiles and reduce cardiovascular disease risk, but effects are variable and may depend on genetic factors. We performed a genetic association analysis of data from 2,993 participants in the Diabetes Prevention Program to test the hypotheses that a genetic risk score (GRS) based on deleterious alleles at 32 lipid-associated single-nucleotide polym

Objective To evaluate the specificity of expression patterns of cell-free circulating microRNAs (miRNAs) in systemic lupus erythematosus (SLE). Methods Total RNA was purified from plasma, and 45 different specific, mature miRNAs were determined using quantitative reverse transcriptionpolymerase chain reaction assays. A total of 409 plasma samples were obtained from 364 different patients with SLE,

FTO is the strongest known genetic susceptibility locus for obesity. Experimental studies in animals suggest the potential roles of FTO in regulating food intake. The interactive relation among FTO variants, dietary intake and body mass index (BMI) is complex and results from previous often small-scale studies in humans are highly inconsistent. We performed large-scale analyses based on data from

Degenerative changes of the lumbar spine may lead to misinterpretation of bone mineral density (BMD) measurements and cause underdiagnosis of osteoporosis. This longitudinal study of 1,044 women, 75 years at inclusion and followed for 10 years, shows that identification of apparent degenerative changes on the dual energy X-ray absorptiometry (DXA) scan can increase the proportion diagnosed. INTR

Popular Abstract in Swedish Mesenteriell ischemi (nedsatt blodcirkulation till tarm och övriga bukorgan) är vanligt förekommande vid ett flertal olika sjukdomstillstånd som t ex blödnings-, septisk och cirkulatorisk chock. Inte minst är tarmen mycket känslig för nedsättning av blodflödet. Tarmskadan, inkluderande dess barriär(skydds-)funktion sker dels under perioden med nedsatt blodförsörjning meIntestinal ischemia and reperfusion (I/R) is not infrequent in the clinical situation and the intestinal barrier plays an important role in gut barrier function, preventing not at least septic complications and potentially the development of the multiple organ dysfunction syndrome. Mechanisms of intestinal I/R induced gut epithelial and endothelial barrier dysfunction and remote organ dysfunction

Popular Abstract in Swedish Polymergeler och deras interaktioner med joniska surfaktanter. Olika typer av hydrofoba polymerer och hydrophobmodifierade polymerer tvärbinds kemisk till geler. Dessa geler tillhör gruppen responsiva geler, vilket betyder att gelerna ändrar sin volym under yttre påverkan. Gelernas volymändring studeras vid tillsats av olika joniska surfaktanter, vid tillsats av saltThe response on chemically crosslinked gels and polymer solutions on the addition of ionic surfactants and/or addition of salt at different temperatures have been studied. All polymers studied are water soluble and slightly hydrophobic or hydrophobically modified. Because of their hydrophobicity the polymers have a strong tendency to associate, both with themselves and with surfactants. Another i