Filetype
Background and aims Curative surgery saves ≈50% of all patients with colorectal cancer (CRC) while remaining patients have synchronous or will develop metachronous metastases. Presently, the single most important prognostic factor is histopathological detection of disseminated tumor cells in regional lymph nodes. However, the routine method has several limitations. The aim was to identify biomarke
This article offers the first empirical and cross‐national analysis of citizens’ views about the democratic importance of the public sphere. We first identify three normative functions that public spheres are expected to perform in representative democracies: they provide voice to alternative perspectives, they empower citizens to criticise political authorities and they disseminate information on
Decomposition of litter is a key biochemical process that regulates the rate and magnitude of CO2 fluxes from biosphere to atmosphere and determines soil nutrient availability. Although several studies have shown that plant litter decomposition accelerated in their native compared to a foreign environment, that is, a home-field advantage (HFA) for litter degradation, to date HFA has only been cons
Background: The dual antiplatelet therapy (DAPT) score guides decisions on DAPT duration after coronary stenting by simultaneously predicting ischemic and bleeding risk. Objectives: This study sought to assess the performance of the DAPT score in a nationwide real-world population. Methods: The study used register data in Sweden (2006 to 2014) and followed 41,101 patients who had undergone 12 mont
A total of 16 global chemistry transport models and general circulation models have participated in this study; 14 models have been evaluated with regard to their ability to reproduce the near-surface observed number concentration of aerosol particles and cloud condensation nuclei (CCN), as well as derived cloud droplet number concentration (CDNC). Model results for the period 2011-2015 are compar
Purpose: To demonstrate the feasibility of multidimensional diffusion MRI to probe and quantify microscopic fractional anisotropy (µFA) in human kidneys in vivo. Methods: Linear tensor encoded (LTE) and spherical tensor encoded (STE) renal diffusion MRI scans were performed in 10 healthy volunteers. Respiratory triggering and image registration were used to minimize motion artefacts during the acq
Purpose: There is currently no molecular signature in clinical use for adjuvant endocrine therapy omission in breast cancer. Given the unique trial design of SweBCG91-RT, where adjuvant endocrine and chemotherapy were largely unadministered, we sought to evaluate the potential of transcriptomic profiling for identifying patients who may be spared adjuvant endocrine therapy. Experimental Design: We
Objective- RAGE (receptor for advanced glycation end products) and EMMPRIN (extracellular matrix metalloproteinase inducer) are immune receptors for proinflammatory mediators. These receptors can also be found in a soluble form in the circulation. Soluble RAGE (sRAGE) has shown atheroprotective properties in animal studies, possibly by acting as a decoy receptor for its ligands. Whether sEMMPRIN (
Normative reasons are of constant importance to us as agents trying to navigate through life. For this reason it is natural and vital to ask philosophical questions about reasons and the normative realm. This thesis explores various issues concerning reasons and normativity. The thesis consists of five free-standingpapers and an extended introduction. The aim of the extended introduction is not me
Chylomicrons labeled with [3H]arachidonic and [14C]linoleic acid were incubated with bovine milk lipoprotein lipase or rat postheparin plasma, containing both lipoprotein lipase and hepatic lipase. During incubation with bovine lipoprotein lipase, [3H]arachidonic acid was released from chylomicron triacylglycerols at a slower rate than [14C]linoleic acid. Only small amounts of [14C]linoleic acid w
The objective of this study was to probe the molecular mechanisms underlying the increase in sensitivity of cells to bradykinin (BK) following expression of a transforming Ha-ras oncogene. We used native NIH3T3 fibroblast (3T3) cells and 3T3 cells transfected with a glucocorticoid-sensitive oncogenic Ha-ras construct (DT cells). DT cells incubated in the presence of 1 μM dexamethasone (DEX) for 24
Chemical cross-linking combined with site-directed mutagenesis was used to evaluate the role of extracellular cysteines and their positions relative to the binding site for the agonist bradykinin (BK) in the human BK B2 receptor. All extracellular cysteines, Cys20, Cys103, Cys184, and Cys277, in the receptor were mutated to serines, and single and double mutants were transfected into COS-7 cells.
We have previously shown that exposure of DDT1 MF-2 smooth muscle cells to the agonist bradykinin (BK) resuits in a rapid B2 kinin receptor-mediated internalization of BK followed by degradation of the intracellular BK [Munoz, C. M., and Leeb-Lundberg, L. M. F. (1992) J. Biol. Chem. 267, 303-309]. Here, we show that BK internalization is paralleled by sequestration of the occupied B2 receptors. Se
Traditionally, sample work-up has been associated with different kinds of liquid extraction techniques involving a large consumption of hazardous solvents. There are today regulations that aims at replacement of dangerous chemicals which has created a need for new extraction techniques. During the last decade supercritical fluid extraction (SFE) has become a good alternative for sample pretreatme
In the autumn of 1993 the subject of free trade in visual media was brought into the public eye as never before, at least within the European Union. The occasion was of course the much publicised near breakdown in the ongoing GATT-negotiations. The crux seemed to be that the US and the EU was unable to come to terms whereas films and television programmes was to be seen as manufactured goods which
We have fit synthetic visibilities from 3-D (CO5BOLD +PHOENIX) and 1-D (PHOENIX, ATLAS12) model stellar atmospheres forProcyon (F5 IV) to high-precision interferometric data from the VINCIinstrument at the VLT Interferometer (K-band) and from the Mark IIIinterferometer (500 nm, 800 nm). These data provide a test oftheoretical wavelength-dependent limb-darkening predictions, andtherefore
LU-template English 16:9 Faculty of Science Lund university 1 We are united in our efforts to understand, explain and improve our world and the human condition. 2 The faculty in numbers 8 departments or other units 1 085 employees (995 full-time equivalents) 2 922 students (1 626 full-time equivalents) Bachelor’s programme with 12 specialisations (3 in English) The hospital physics programme 18 ma
https://www.science.lu.se/internal/sites/science.lu.se.internal/files/2023-04/faculty-of-science-2022.pptx - 2026-07-22
Microsoft Word - Radslans_geografi_ver4 JF_test1_EF.docx #17 SÄKERT! Upplevd trygghet på svenska besöksmål EN RAPPORT FRÅN2021 2 / S Ä K E R T ! – U P P L E V D T R Y G G H E T P Å S V E N S K A B E S Ö K S M Å L 3 5 7 10 15 24 29 INNEHÅLLSFÖRTECKNING 1/ INLEDNING 2/ SLUTSATSER 3/ FORSKARNAS REKOMMENDATIONER 4/ ”KEEP CALM AND CARRY ON” 5/ TRE RÖSTER OM SÄKRA DESTINATIONER 6/ OM FORSKNINGSPROJEKTET
https://www.isk.lu.se/sites/isk.lu.se/files/2021-03/BFUF_17_Sakert_20210318.pdf - 2026-07-22
Modern science, as we today know it has its roots in Europe during the renaissance, philosophers then begun to form knowledge on the rules for how nature science should work in its quest in understanding the universe. The seventeenth century was also when scientific journals came into circulation, this represents a great leap in how science was communicated in contrast to earlier private correspon
PowerPoint Presentation E-learning Module 1 Scanning at 7T Introduction This module introduces main elements that differentiates scanning at 7T from scanning at 3T, from a users perspective. Aspects of 7T physics are described, and examples of how that impact scanning will be given, with a focus on the additional challenges of scanning at 7T. In the end is a small quiz that can be used for testing
https://www.lbic.lu.se/sites/lbic.lu.se/files/philips_e-learning_7t.ppsx - 2026-07-22
