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The Environmental Determinants of Diabetes in the Young (TEDDY) Study IMMUNOLOGY OF DIABETES V The Environmental Determinants of Diabetes in the Young (TEDDY) Study TEDDY Study Group The etiology of type 1 diabetes (T1D) remains unknown, but a growing body of evidence points to infectious agents and/or components of early childhood diet. The National Institutes of Health has established the TEDDY

https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_06_teddy_study_group_nyas_2008.pdf - 2026-07-12

Parental Estimation of Their Child’s Increased Type 1 Diabetes Risk During the First 2 Years of Participation in an International Observational Study Journal of Empirical Research on Human Research Ethics 2016, Vol. 11(2) 106–114 © The Author(s) 2016 Reprints and permissions: sagepub.com/journalsPermissions.nav DOI: 10.1177/1556264616648589 jre.sagepub.com Research Concerning Young People Type 1 d

https://www.teddy.lu.se/sites/teddy.lu.se/files/09092016_679_56_mp67_swartling_jerhre_2016.pdf - 2026-07-12

Objectives: We previously found large variations in general practitioner (GP) hypertension treatment probability in oldest-old (>80 years) between countries. We wanted to explore whether differences in country-specific cardiovascular disease (CVD) burden and life expectancy could explain the differences. Design: This is a survey study using case-vignettes of oldest-old patients with different como

Elastic fibers containing elastin play an important role in tendon functionality, but the knowledge on presence and function of elastin during tendon healing is limited. The aim of this study was to investigate elastin content and distribution in intact and healing Achilles tendons and to understand how elastin influence the viscoelastic properties of tendons. The right Achilles tendon was complet

Summary: Vertebral fractures are independent risk factors for vertebral and nonvertebral fractures. Since vertebral fractures are often missed, the relatively new introduction of vertebral fracture assessment (VFA) for imaging of the lateral spine during DXA-measurement of the spine and hips may contribute to detect vertebral fractures. We advocate performing a VFA in all patients with a recent fr

Electromagnetic fields exist all around us. Through evolution, nature has developed tools to interact and use these fields, where our eyes are a spectacular example. Humans have a long history of developing structures and objects of their own to alter and interact with these fields. Today they are important cornerstones in society, with radiating devices such as cell phones, Wi-Fi routers, or car

Memory clinic patients are a heterogeneous population representing various aetiologies of pathological aging. It is unknown if divergent spatiotemporal progression patterns of brain atrophy, as previously described in Alzheimer's disease (AD) patients, are prevalent and clinically meaningful in this group of older adults. To uncover distinct atrophy subtypes, we applied the Subtype and Stage Infer

Background Urine cadmium (Cd) and renal function biomarkers, mostly analysed in urine spot samples, are well established biomarkers of occupational exposure. Their use and associations at low environmental level are common, but have recently been questioned, particularly in terms of physiological variability and normalisation bias in the case of urine spot samples. Aim To determine the appropriate

Background: Adult hip dysplasia is one of the few potentially modifiable risk factors for hip osteoarthritis (OA). However, the prevalence of hip dysplasia and the strength of its association with OA are not fullyunderstood.Aims and methods:I. To determine the prevalence of hip dysplasia in a Swedish population and investigate whether the condition was mentioned in radiology reports. The center ed

This thesis conceptually consists of two parts. The fist part---the first half of paper I and papers II--IV---is a study of Jensen measures and their role in pluripotential theory. Lately, there have been a great interest in new methods for constructing plurisubharmonic functions as lower envelopes of disc functionals in the spirit of Poletsky. In this context, Jensen measures of various types pla

The Murray Basin is a low-lying but extensive intracratonic depocentre in southeastern Australia, preserving an extraordinary record of Late Neogene sedimentation. New stratigraphic and sedimento-logic data allow the long-term evolution of the basin to be re-evaluated and suggest a significant role for: (1) tectonism in controlling basin evolution, and (2) progressive and step-wise climatic change

Background: Human immunodeficiency virus type 1 (HIV-1) is one of the fastest-evolving human pathogens. Understanding HIV-1 transmission, within-host adaptation, and evolutionary dynamics is pivotal for development of interventions and vaccines. HIV-1 infection is generally caused by a single transmitted founder virus (TFV), and TFV sequences are typically obtained using single genome amplificatio

Popular Abstract in Swedish Avhandlingen behandlar barns flyttningar hemifrån i det förindustriella bondesamhället. Utöver att studera när barn lämnade hemmet kopplas också flyttningsprocessen till den förindustriella hushållsekonomins funktionssätt. Analysen görs på ett longitudinellt material för ett område i västra Skåne under perioden 1829-1866. Individerna följs från födseln, eller från det aThis study deals with the process of children leaving home and its interactions with the household economy in preindustrial society. A theoretical model of leaving home is outlined and then analyzed multivariately, using a longitudinal micro-level dataset for a sample of parishes in western Scania, Sweden, for the period 1829-1866. In a first introductory part the social and economic background as

Popular Abstract in Swedish Syftet med den här avhandlingen har varit att förstå hur grupper av vi och dom skapas och består, framför allt inom utbildning och skola, och särskilt inom gymnasiala Komvux. I vardagligt tal menar människor oftast att dom är invandrare, medan vi är svenskar. Jag har visat att denna uppdelning, som sker nästan automatiskt, är alltför förenklad och svart-vit. Ett undersyThis thesis, set in an educational context (Swedish Komvux, high school adult education), deals with how groups of us and them are constructed, changed and reproduced. In order to understand the processes of us and them I have looked at the interconnections between gender, ethnicity and class utilising participant observations and semi-structured interviews. The main theoretical points of departu

Popular Abstract in Swedish Denna studie handlar om mediereception som pedagogisk form och meningsskapande över tid. Jag är intresserad av att förstå komplexitet i meningsskapande processer som utgår från medieproduktioner. Syftet med avhandlingen är att undersöka vad mötet mellan en grupp lärarstudenter och deras texter kan erbjuda för möjligheter och begränsningar för meningsskapande över tid i The present study is about media reception as an educational form, supporting meaning-making over time. The thesis stems from the desire to understand the complexity in a meaning-making process that takes its point of departure in media productions. The aim is to investigate the possibilities and limitations for meaning-making over time, afforded by the meeting of a group of student teachers and t

High resolution palaeoenvironmental records in Far-Eastern Russia are rare, and the Kamchatka Peninsula is among the least studied areas of the region. This paper describes a record spanning the last ca. 11,000 yr, obtained from a bog in the southern part of Kamchatka. The radiocarbon dated core was analysed for pollen, testate amoebae, charcoal and loss-on-ignition (LOI). The vegetation during th

Popular Abstract in Swedish ”Stat och kommun i makt(o)balans. En studie av flyktingmottagandet.” Denna avhandling handlar om relationen mellan stat och kommun, närmare bestämt i Sverige idag. Dock ses den inte, såsom brukligt, som en hierarkisk relation utan som ett ömsesidigt beroende där staten och kommunerna är beroende av varandra. Detta ömsesidiga beroende kan vara symmetriskt, att båda aktör Already from the title of this dissertation can two important points be made. The first is that the dissertation is about the relationship between central and local government, more specifically in Sweden today. The second point is that this relationship is seen from a balance of power perspective, where the relative power of the actors is an empirical question rather than derived from a given hi

During my time as Director of Studies at the Municipal Music School of Lund, Sweden, I have had several discussions with teachers, students, parents, municipality civil servants, and politicians. I have concluded that in general, culture schools and music schools are looked upon as institutions where parents safely can send their children convinced about that they get a qualified education regardi

Popular Abstract in Swedish Cancerförekomst i familjen är en riskfaktor för flera vanliga cancerformer. Såväl ärftlig (hereditär) som icke-ärftlig (sporadisk) cancer är resultatet av en ansamling av förändringar (mutationer) i gener vars normala funktion är att reglera cellernas delning, tillväxt och mognad. Vid ärftlig cancer finns den första erforderliga mutationen i kroppenThis thesis focuses on one of the most common types of hereditary cancer, hereditary nonpolyposis colorectal cancer (HNPCC). This syndrome is characterized by an autosomal dominant inheritance, an increased risk for several types of cancer (especially cancer of the colorectum, small bowel, endometrium, ovary and urinary tract), early age at diagnosis, and frequent development of multiple primary m

Objective: Needle acupuncture in small children has gained some acceptance in Western medicine. It is controversial, as infants and toddlers are unable to consent to treatment. We aimed to assess its efficacy for treating infantile colic. Design: A systematic review and a blinding-test validation based on individual patient data from randomised controlled trials. Primary end-points were crying tim