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Introduction: Development of industrial yeast strains with high tolerance towards the inhibitors released during biomass pretreatment is critical for bioethanol production. Combining this trait with increased thermotolerance would result in a more efficient production via Simultaneous Saccharification and Fermentation (SSF) as well as reduced cooling costs. The aim of the present work was to devel
In topology optimization, iterative, gradient-based methods are used to find the material distribution of structures which maximizes some objective function, typically the structures' stiffness, or in some cases the fundamental frequency. Finite element analysis is used to compute the structural response in each iteration, leading to large systems of equations. Several hundred iterations may b
This study aims to highlight and evaluate current energy policy instruments for supervising the work on energy verification of buildings. The verification is directed to be performed by each municipality. Energy verification is aimed to present a buildings real energy use. It will also confirm or deny that the building meets the requirements in the National Board of Housing’s building regulations
This study investigates the barriers that high-skilled Asian immigrant entrepreneurs have in the process of starting their entrepreneurial ventures outside of Asia. The study interviewed eight high-skilled Asian immigrant entrepreneurs from Sweden, Germany, France, and USA. The study uses five theoretical frameworks to investigate the barriers, which are: cultural barriers, social capital, human c
Tracking objects in a scene is a crucial task in accomplishing surveillance that enhances security and provides valuable information about the events happening at the site. For this task, the PTZ (pan-tilt-zoom) cameras can be utilized to achieve fluid tracking as they provide all-around surveillance with zoom capabilities. The drawback of current tracking solutions is the lack of interoperability
Denna rapport beskriver arbetet med att ta fram en landseglare i samarbete med konsultföretaget Semcon. Företaget vill kunna använda produkten på mässor och events, därför ska produkten ska utstråla Semcons värdeord, vilka är ”Responsibility, Credibility, Excellence”. Målet med arbetet är att skapa en landseglare som är mera portabel och enklare att montera jämfört med befintliga på marknaden, menThis report describes the development of a land sailer together with the consulting company Semcon. The company wants to use the product at fairs and internal events, therefore shall the product reflect Semcons core values, which are “Responsibility, Credibility, Excellence”. The aim with the development is to create a land sailer which is more portable and easier to assemble compared to existing
This thesis investigates the Swedish media’s reporting on the VW emission scandal that took place in the fall of 2015. By using a qualitative approach data was collected from three of Sweden’s largest newspapers; Aftonbladet, Expressen and Dagens Nyheter and processed with analytic tools and content analysis inspired by CDA. The aim of this study is to gain a fundamental understanding of the dynam
Formulating and implementing a new strategy may be a challenging task, especially if it alters the way in which a company has operated and positioned itself before. This may be particularly true for companies within the forest industry, like manufacturers of paper packaging products, pursuing differentiated customer value and innovative solutions where, traditionally, success has been measured in
Popular Abstract in Swedish Polymerer är samlingsnamnet på långa molekylkedjor. Runt omkring oss i vårt dagliga liv är vi omgärdade av polymerer så som plaster, lim, fibrer och proteiner. Utvecklingen av många högteknologiska produkter är starkt beroende av polymera material. Grundläggande kunskaper om dem och deras egenskaper är därför viktigt. I ett batteri kan många fördelar erhållas då den koThere is a growing need for multifunctional polymeric materials for the development of several important energy conversion technologies. For example, the polymer electrolyte is a key component in lithium polymer batteries. The basic functions of this electrolyte are to efficiently conduct the lithium ions and physically separate the electrodes. Consequently, these electrolytes should ideally posse
Purpose Primary lung adenocarcinoma remains a deadly disease. Gene expression phenotypes (GEPs) in adenocarcinoma have potential to provide clinically relevant disease stratification for improved prognosis and treatment prediction, given appropriate clinical and methodological validation. Experimental Design 2395 transcriptional adenocarcinoma profiles were assembled from 17 public cohorts and cla
Joint diseases are often characterized by inflammatory processes that result in pathological changes in joint tissues, including cartilage degradation and release of components into the synovial fluid. The complement system plays a central role in promoting the inflammation. Because several cartilage proteins are known to interact with complement, causing either activation or inhibition of the sys
Creatine kinases are important in maintaining cellular-energy homeostasis, and neuroprotective effects have been attributed to the administration of creatine and creatine-like compounds. Herein we examine whether ablation of the cytosolic brain-type creatine kinase (B-CK) in mice has detrimental effects on brain development, physiological integrity or task performance. Mice deficient in B-CK (B-CK
Although relatively rare, Huntington’s disease (HD) has fatal consequences. There is no cure for the disease, which leads to an early death. Worldwide, scientists are trying to develop therapeutic methods that could cure the disease, including new molecular gene therapeutic methods. At Lund University, research on HD is now about to step from animal models to trials with humans. The project is spe
A recent upsurge in rights talk has left a mark on many areas of law and social policy. Areas such as freedom of expression and hate speech that have traditionally been debated in terms of rights, as well as family law and the welfare of children, human trafficking and prostitution, national security and anti-terrorism legislation, economic policy and market development, to mention but a few, have
The orbit of a planet is surrounded by a chaotic zone wherein nearby particles' orbits are chaotic and unstable. It was shown by Wisdom that the chaos is driven by the overlapping of mean motion resonances which occurs within a distance (δa/a)chaos≈ 1.3μ^2/7 of the planet's orbit. However, the width of mean motion resonances grows with the particles' eccentricity, which will increase the width of
The impact of warmer climate on melt and evaporation was studied for tainted, snowfed and glacierfed basins located in the western Himalayan region. Hydrological processes were simulated under current climatic conditions using a conceptual hydrological model, which accounts for the rainfall-runoff, evaporation losses, snow and glacier melt. After simulations of daily observed strearnflow (R-2 = 0.
CD40 is a cell surface receptor initially discovered on cells of the hemopoietic lineage. Its primary role on immune cells is to enhance their activation and hence their production of cytokines and immunomodulatory molecules. Recently, CD40 has also been detected on human fibroblasts. An emerging view of the fibroblast is that it is far more than a structural cell, being capable of intimate intera
Embryogenesis of the retina is a complex event orchestrated by a multitude of physical and biochemical signals. To study the impact of intrinsic developmental cues, the retinal tissue can be isolated in culture which also enables modulation of normal development for other purposes, i.e. transplantation of specific neuronal cell types. In the present experiment, cell type development of immature po
Background-The time course and magnitude of infarct involution, functional recovery, and normalization of infarct-related electrocardiographic (ECG) changes after acute myocardial infarction (MI) are not completely known in humans. We sought to explore these processes early after MI and during infarct-healing using cardiac MRI. Methods and Results-Twenty-two patients with reperfused first-time MI
