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During winter at temperate and high latitudes, the low ambient temperatures, limited food supplies and short foraging periods mean small passerines show behavioural, morphological and physiological adaptations to reduce the risk of facing energy shortages. Peripheral tissues vasoconstrict in low ambient temperatures to reduce heat loss and cold injury. Peripheral vasoconstriction has been observed
This article discusses the implications of the United Nations’ Convention on the Rights of Persons with Disabilities (“CRPD”) for domestic policies on research involving persons with disabilities, including those with limited decision-making abilities. It starts with an examination of the protection the Convention affords to persons with disabilities against being enrolled in research projects, an
Compartmentalized microfluidic platforms are an invaluable tool in neuroscience research. However, harnessing the full potential of this technology remains hindered by the lack of a simple fabrication approach for the creation of intricate device architectures with high-aspect ratio features. Here, a hybrid additive manufacturing approach is presented for the fabrication of open-well compartmental
The main objective was to develop a wipe sampling test to measure surface contamination of the most frequently used antineoplastic drugs (ADs) in Swedish healthcare and, furthermore, to develop an analysis method sensitive enough to assess low levels of contamination. Two wipe sampling tests with separate sample processing methods assessing (i) cyclophosphamide (CP), ifosfamide (IF), 5-fluorouraci
Background: Anorexia nervosa (AN) is a life-threatening illness. Sometimes long inpatient treatment is necessary, increasing the anxiety that comes with hospitalization and the necessary weight gain. Safe, non-pharmacological adjunctive therapies that improve subjective health are called for. Objective: The aim of this non-randomized, mixed-methods observational study was to describe the utilizati
Purpose: To explore school-aged children's experiences about their best interests and participation in care during a hospital admission. Design and methods: A descriptive qualitative design involving in-depth, iterative inductive review of child responses to generate key words that led to identification of categories and themes. The study was guided by the United Nations Convention on the Rights o
Objectives: We aim to define whether the timing of microaxial left ventricular assist device (IMLVAD) implantation might impact on mortality in acute myocardial infarction (AMI) cardiogenic shock (CS) patients who underwent primary percutaneous coronary intervention (PPCI). Background: Despite the widespread use of PPCI, mortality in patients with AMI and CS remains high. Mechanical circulatory su
In the fields of medicine and biology, the separation of particles is a central step in many preparative and analytical processes. Deterministic Lateral Displacement (DLD) has been a promising technique in the field of microfluidic particle and cell sorting, specifically for label-free separation with several applications of sorting by size, morphology, and deformation reported in the literature o
Eucalyptus plantations have been established in many areas of the world due to their fast growth and profitability. In NW Spain, Eucalyptus plantations now cover a larger area than native forests. Although Eucalyptus plantations have been shown to affect biodiversity, relatively few studies have compared their effect on multiple taxonomic groups and different aspects of biodiversity. We compared h
To evaluate the diagnostic yield of the ECG criteria for ST-elevation myocardial infarction in a large cohort of emergency department chest pain patients, and to determine whether extended ECG criteria or reciprocal ST depression can improve accuracy. Design: Observational, register-based diagnostic study on the accuracy of ECG criteria for ST-elevation myocardial infarction. Between Jan 2010 and
BACKGROUND: Quinoa (Chenopodium quinoa Willd.) flour and processed traditional Peruvian quinoa breakfast foods were studied to evaluate the effect of extrusion and post-processing on protein properties, morphology and nutritional characteristics (amino acids and dietary fibers). RESULTS: The extrusion increased quinoa protein crosslinking and aggregation observed by size exclusion high-performance
Previous investigations have identified the roles of knee joint muscles in supporting external loads during non-weight-bearing tasks and found these to depend on moment arm orientation (MAO). However, during weight-bearing tasks ground reaction forces (GRF) are transferred up through the knee, subjecting it to large multi-directional forces and stability is dependent on articular geometry, loading
Background: Women with mild breast cancer-related arm lymphedema (BCRAL) mostly receive treatment with compression garments and instructions in self-care to prevent the progression of lymphedema. However, wearing a compression garment may be experienced as negative and may affect health-related quality of life (HRQOL) more than the lymphedema itself. The aim of this study was to investigate if the
Three interlaboratory tests conducted by European laboratories were studied, in which 37 laboratories participated in 2018, rising to 46 in 2019 and 2020. A RTFO-aged neat bitumen 20/30 and PMB 45/80-55 in RTFO-aged and unaged conditions were tested using a DSR at frequency of 1.59 Hz with PP08 and PP25 geometries at temperatures ranging from 10°C to 65°C. To assess variation in numerous areas of
This chapter departs from two research projects to present the learnings, methodological challenges, and recommendations when involving users in participatory approaches of design research in home care. In the first project, older participants collected data through solicited diaries and photo elicitation, reflecting about their use of multiple medications and difficulties experienced with medicat
Objective: Late night spontaneous growth hormone (GH) pulses may influence the pituitary GH response to provocation tests. We evaluated GH response during arginine-insulin-tolerance test (AITT) after a GH peak during a short spontaneous nocturnal profile (SSNP) in children with short stature or low growth velocity. Design: Using SSNP and subsequent AITT, we examined 257 children 4–18 years old (13
An installation for testing techniques related to seeding and harmonic generation has been completed at MAXlab. The aim is to study the processes around seeded harmonic generation at 130/88/54 nm, the 2/3/5 harmonic of a Ti: Sapphire laser. During the spring 2008 the commissioning work has begun and this paper will report on the progress. The test FEL is built around the existing linac injector at
BACKGROUND AND AIM: Cigarette smoking is the most common cause of chronic obstructive pulmonary disease (COPD) but more mechanistic studies are needed. Cigarette smoke extract (CSE) can elicit a strong response in many COPD-related cell types, but no studies have been performed in lung fibroblasts. Therefore, we aimed to investigate the effect of CSE on gene expression in lung fibroblasts from hea
OBJECTIVES: To investigate whether the relative effectiveness of janus kinase inhibitors (JAKis) versus tumour necrosis factor inhibitors (TNFi) or other biological disease-modifying antirheumatic drugs in rheumatoid arthritis differ by the presence or absence of risk factors for cardiovascular (CV) disease, age, sex and smoking. METHODS: Through Swedish registers, we identified 13 493 individuals
