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Over the years consumer packaging has become increasingly important as a value-adding element, since packages shape the consumer’s experience with the product during use, as well as accelerate the purchase decision. From a prod-uct/service system perspective, the strategic benefits of viewing packaging as a central value carrier are evident. To consumers, the product and its packaging are often pe
This paper presents a study with the intent to examine the opportunities provided by creating and using simulation models of software development processes. A model of one software development project was created through means of system dynamics, with data collected from documents, interviews and observations. The model was simulated in a commercial simulation tool. The simulation runs indicate th
Popular Abstract in Swedish Blodbildningen är en av kroppens livligaste processer. Varje dag bildas det upp mot en triljon (12 nollor!) mogna blodceller. De röda blodkropparna står för transporten av syre, de vita blodkropparna försvarar mot infektioner och trombocyterna deltar i blodlevringen. Bildningen av blodceller sker i benmärgen och kan liknas vid ett träd, där roten utgörs av de så kalladeGranulocyte-macrophage- (GM-) and granulocyte- (G-) colony stimulating factor (CSF) are important cytokines in the regulation of hematopoiesis and for the function of mature blood cells. They are also involved in the cytokine network regulating the inflammatory and immune response. The aim of this study was to investigate the regulation of GM- and G-CSF production at the cellular level. The studie
Popular Abstract in Swedish Arbetet i denna avhandling syftar till att förbättra etanolproduktionen från lignocellulosa. Etanol framställd från förnyelsebara råvaror har fått förnyad uppmärksamhet på grund av den växande medvetenheten om den globala uppvärmningen och farhågor för en trytande tillgång på olja. Lignocellulosa utgör en potentiell råmaterialkälla för framtida storskalig etanolproduktiThe work presented in this thesis has been aiming at improving ethanol production from lignocellulose. Ethanol from renewable resources is receiving renewed attention due to apprehensions of global warming and dwindling oil reserves. Lignocellulose constitutes a potential raw material source for large scale ethanol production. To produce ethanol from lignocellulose, the hemicellulose and cellulose
Popular Abstract in Swedish Måndagen den 16:e april 2001 informerade det amerikanska företaget Cisco, med produkter och tjänster inom nätverk och datakommunikation, att de skulle skriva ned sitt komponentlager med 2,2 miljarder dollar. Detta skedde i samband med en globalt vikande efterfrågan och det som skulle komma att kallas IT-bubblan i folkmun. Investerare och företagsledning ställde sig fråg
This chapter describes and analyzes the public relations strategies and practices of a public organization, a local rescue services, in the process of establishing credibility and building trust in multicultural areas. The trust-building efforts are a response to several years of social unrest, communicative clashes and hostile treatment between operative firemen and residents in certain areas. Th
Wetland creation at large, regional scales is implemented as a measure to abate the biodiversity loss in agricultural landscapes and the eutrophication of watersheds and coastal areas by non-point source nutrient pollution (mainly nitrogen). The consequences of creating many new wetlands for biodiversity conservation and nutrient retention (ecosystem functioning) in agricultural landscapes are sti
Objectives: The vascular biology of restenosis is complex and not fully understood, thus explaining the lack of effective therapy for its prevention in clinical settings. The role of c-Myc in arteriotomy-induced stenosis, smooth muscle cell (SMC) differentiation and apoptosis was investigated in rat carotids applying full phosphorothioate antisense ( AS) oligonucleotides (ODNs). Methods: Carotid a
Background: Blood lipid levels including low-density lipoprotein cholesterol ( LDL-C), high-density lipoprotein cholesterol ( HDL-C), and triglycerides ( TG) are highly heritable. Genome-wide association is a promising approach to map genetic loci related to these heritable phenotypes. Methods: In 1087 Framingham Heart Study Offspring cohort participants ( mean age 47 years, 52% women), we conduct
The aim of this study was to describe the experiences of undergoing a presymptomatic genetic test for the hereditary and fatal Huntington's disease, using a case study approach. The study was based on 18 interviews with a young woman and her husband from the decision to undergo the test, to receiving the results and trying to adapt to them, which were analysed using a life history approach. The fi
Light is both the energy source and the dominant signalling input for photosynthetic organisms. Accordingly, up to 30–50% of the genes expressed in plant leaves are directly or indirectly regulated by light, and virtually all aspects of plant metabolism support photosynthesis, depend upon the products of photosynthesis or are affected by photosynthesis-related changes in metabolite levels. Though
Background: Free and total human kallikrein 2 (hK2) might improve the discrimination between prostate cancer and benign prostatic hyperplasia. Concentrations of hK2 are 100-fold lower than concentrations of prostate-specific antigen (PSA); therefore, an hK2 assay must have a low detection limit and good specificity. Methods: PSA- and hK2-specific monoclonal antibodies were used in solid-phase, two
The copolymer of N-isopropylacrylamide (NIPAM) and methacryloyl derivative of spirobenzopyran (MSBP) with a molecular weight of 21 000 g/mol and the average molar MSBP content of 1.9% was prepared by free radical polymerization. The copolymer displayed its phase transition in water in the temperature range of 30-50 degreesC. UV irradiation of its aqueous solution caused photoinduced transformation
Popular Abstract in Swedish Det övergripande syftet för denna avhandling är att bidra till utvecklingen av en teori om förändringsarbete och lärande i arbetslivet. De specifika förändringsprocesser som studerades skedde inom ramen för en interaktiv förändringsansats som syftade till en emancipatorisk utveckling: att de anställda skulle få ökat inflytande över sin arbetssituation, vilket i sin tur The general aim of the investigation is to contribute to the development of a theory of change and learning within the working environment. The specific change processes that were examined, emerged from an interactive initiative for change, intending to facilitate an emancipatory development: employees increasing their control of the work situation, thus improving the quality of service. The empir
Smoking is a risk factor for developing chronic obstructive pulmonary disease (COPD), but there are no good indicators for early identification of subjects who will develop symptomatic COPD. The aim of this study was to investigate inflammatory mechanisms related to changes in lung function and emphysematous changes on high resolution computed tomography (HRCT) in 'healthy' smokers. Subjects were
alpha-Cells were identified in preparations of dispersed mouse islets by immunofluorescence microscopy. A high fraction of alpha-cells correlated with a small cell size measured as the average cell diameter (10 microm) and whole-cell capacitance (<4 pF). The alpha-cells generated action potentials at a low frequency (1 Hz) in the absence of glucose. These action potentials were reversibly inhibite
European air traffic control is undergoing changes in organization and technology in order to increase efficiency in air traffic. Change processes can have a negative impact on existing safety cultures, the foundations of safety work, and on safety. This paper reports on an assessment of safety culture at one administrative and two operative units in a Swedish air traffic control setting, using qu
BACKGROUND: Previous studies have shown that short-term treatment with adrenocorticotrophic hormone (ACTH) has a strong and rapid lipid-lowering effect. In this long-term study of nephrotic patients with idiopathic membranous nephropathy, the influence of ACTH on the serum lipoprotein profile and glomerular function as well as the dose-effect relationship was investigated. METHODS: Fourteen patien
[1] Vigorous debate still surrounds the cloud electrification process and unexplained regional variations in lightning activity. Here, we show that climatological maxima in lightning activity are associated with small effective diameter D-e of ice crystals near cumulonimbus cloud tops. This relationship, unlike lightning's more well-known relationship with cloud top height, is consistent over land
