Filetype
Objectives: To study: (I) work-loss seen as sick leave and disability pension before and after the start of first anti-TNF therapy in Swedish regional and national RA cohorts; (II) baseline predictors of a good future work prognosis at diagnosis and after anti-TNF start with a special focus on the impact of the disease activity level and the disease duration at treatment start. Methods: RA patie
OBJECTIVE: To study the association of physician's sex with blood pressure, lipid control, and cardiovascular risk factors in treated hypertensive men and women, stratified for the sex of their physician. METHODS: In a cross-sectional survey of hypertensive patients, 264 primary care physicians (PCPs), 187 men and 77 women from across Sweden, recruited 6537 treated hypertensive patients (48% men)
Spectral Doppler ultrasound imaging typically consists of a spectrogram, showing the velocity distribution of the blood, and a brightness (B-) mode image allowing the operator to navigate. It is desirable to have both high spectral and velocity resolution, so that details in the blood flow can be traced, as well as a high B-mode frame rate to allow for tracking of movements and to adjust the posit
A readily releasable pool (RRP) of granules has been proposed to underlie the first phase of insulin secretion. In the present study we combined electron microscopy, insulin secretion measurements and recordings of cell capacitance in an attempt to define this pool ultrastructurally. Mouse pancreatic B-cells contain approximately 9,000 granules, of which 7% are docked below the plasma membrane. Th
Background Whether or not ankles can be replaced with reasonable safety has been the subject of debate. We present the results of a nationwide series of total ankle arthroplasties. Patients and methods All Swedish hospitals that implant or have implanted modern three-component ankle prostheses reported demographic data and date of index and revision surgery to a central register. After the data ha
Popular Abstract in Swedish Vid avdelningen bedrivs forskning bl.a. med inriktning på laserbaserad förbränningsdiagnostik. Att mäta med en laser i olika flammor är en stor fördel eftersom laserljuset är beröringsfritt. Därför kan unika mätresultat erhållas med en minimal påverkan av förbränningsprocessen. Jag har främst arbetar med att utveckla en teknik för att mäta temperaturen 2-dimensionellt. The present thesis is concerned with the development and application of a novel planar laser-induced fluorescence (PLIF) technique for temperature measurements in a variety of combusting flows. Accurate measurement of temperature is an essential task in combustion diagnostics, since temperature is one of the most fundamental quantities for the characterization of combustion processes. The techniqu
The role of the carbohydrates for the structure and functions of the plasma and tissue protein alpha1-microglobulin (alpha1m) was investigated by deletion of the sites for N-glycosylation by site-directed mutagenesis (N17,96-->Q). The mutated cDNA was expressed in a baculovirus-insect cell system resulting in a nonglycosylated protein. The biochemical properties of N17,96Q-alpha1m were compared to
The current development debate emphasizes national ownership of the development agenda as a precondition for sustainable development and aid effectiveness. Vietnam is often held up as a good example of strong ownership. Yet, the ownership concept is not clearly defined or understood due to a lack of empirically rooted evidence and analysis. This study examines the key elements of development owne
This paper investigates the treatment of antonymy in Collins COBUILD Advanced Learner’s English Dictionary (2003) in order to find out what kinds of headwords are provided with antonyms as part of their definitions and also discusses the principles for antonym inclusion in the entries. CCALED includes canonical antonyms such as good/bad and dead/alive, as well as more contextually restricted pairi
The diagnosis of acute otitis media (AOM) is often difficult, depending heavily on the experience and skills of the examiner. However, it is important to identify episodes of AOM that involve the risk of complications and to treat these episodes appropriately. The present study was performed in order to evaluate the use of a rapid antigen assay for Streptococcus pneumoniae, the Binax NOW test, as
Popular Abstract in Swedish Denna avhandling har sin upprinnelse i utvecklingen av en metod för datorvisualis-ering och en metod för participativ ingenjörskonst. De två metoderna är intimt förknippade med varandra och benämns tillsammans “Computer Visualization in Participatory Engineering” (VIPE), något som på svenska skulle kunna benämnas ”Datorvisualisering för Participativ Ingenjörsvetenskap”.This thesis tells the initiation story of a computer visualization methodology and a participatory engineering methodology. The two methodologies are tightly coupled and for the purpose of this thesis, as a unit, named Computer Visualization in Par-ticipatory Engineering (VIPE). VIPE aims at a concurrent focus on technical and economical as well as ergonomic demands, by means of advancing communic
Background: There are no predictors known that can identify COPD patients who will respond to treatment with ICS. Method: We investigated 30 patients (median age 65 (range 44-83, 12 females) with mild to moderately severe COPD. All patients had post bronchodilator FEV1/forced vital capacity ratio of less than 70% and a reversibility of less than 12% and 200 ml from baseline. We wanted to determine
Although most institutions offer some kind of follow-up to patients operated on for colorectal cancer, its value with respect to prolonged survival has been challenged. However, improved results of liver surgery and chemotherapy make it reasonable to assume that a follow-up programme leading to detection of more asymptomatic recurrences would result in improved survival. Liver metastases and extra
A central problem in computer vision is to reconstruct the three-dimensional structure of a scene from a set of two-dimensional images. Traditionally this is done by extracting a set of characteristic points in the scene and to compute a reconstruction of these points. In this thesis we propose a novel method that allows reconstruction of a wider class of objects, including curves and surfaces. As
This thesis consists of four papers that broadly concerns two dierent topics. The rsttopic is so-called barycentric Markov processes. By a barycentric Markov process wemean a process that consists of a point/particle system evolving in (discrete) time,whose evolution depends in some way on the mean value of the current points in thesystem. In common for the three rst papers which are on this topicThis thesis consists of four papers that broadly concerns two dierent topics. The rsttopic is so-called barycentric Markov processes. By a barycentric Markov process wemean a process that consists of a point/particle system evolving in (discrete) time,whose evolution depends in some way on the mean value of the current points in thesystem. In common for the three rst papers which are on this topic
Background & Aims: Non-alcoholic fatty liver disease (NAFLD) has been associated with multiple metabolic abnormalities. By applying a non-targeted metabolomics approach, we aimed at investigating whether serum metabolite profile that associates with NAFLD would differ in its association with NAFLD-related metabolic risk factors. Methods & Results: A total of 233 subjects (mean ± SD: 48.3 ±
Small autonomous surface vehicles (ASV) will need both teleoperation support and redundant positioning technology to comply with expected future regulations. When at sea, they are limited by a satellite communication link with low throughput. We have designed and implemented a graphical user interface (GUI) for teleoperation using a communication link with low throughput, and one positioning syste
Context. We present the early installment of the third Gaia data release, Gaia EDR3, consisting of astrometry and photometry for 1.8 billion sources brighter than magnitude 21, complemented with the list of radial velocities from Gaia DR2. Aims. A summary of the contents of Gaia EDR3 is presented, accompanied by a discussion on the differences with respect to Gaia DR2 and an overview of the main l
There is currently interest in low strain HPHT diamond due to its expected application as various types of X-ray optical elements at Synchrotrons, where the X-ray intensity is becoming progressively too severe for the existing materials. The diamond crystals need to be synthesised with unprecedented lattice quality. In recent measurements at the ID19 beamline of European Synchrotron Radiation Faci
There is perennial debate in comparative politics about electoral institutions, but what characterizes this debate is the lack of consideration for citizens’ perspective. In this paper, we report the results of an original survey conducted on representative samples in 15 West European countries (N = 15,414). We implemented an original instrument to elicit respondents’ views by asking them to rate
