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Proton exchange between titratable amino acid residues and the surrounding solution gives rise to exciting electric processes in proteins. We present a proton titration scheme for studying acid-base equilibria in Metropolis Monte Carlo simulations where salt is treated at the Debye-Huckel level. The method, rooted in the Kirkwood model of impenetrable spheres, is applied on the three milk proteins
Investigation of optimized spatial precision for surface temperature measurements is performed. The temperature is measured by means of two-color ratio imaging with ICCD cameras, using the thermographic phosphor BAM. The precision in temperature is put in relation to the spatial resolution, two quantities which involve a trade-off in this case: the more spatial smoothing the better precision, but
Background and purpose The Scandinavian Sarcoma Group (SSG) XIV protocol is based on experience from previous SSG trials and other osteosarcoma intergroup trials, and has been considered the best standard of care for patients with extremity localized, non-metastatic osteosarcoma. We analyzed the outcome in 63 consecutive patients. Patients and methods From 2001 through 2005, 63 patients recruited
In recent years, the discourse of ‘relevance’ has risen to prominence in the university-based business school. At the heart of this discourse is the suggestion that management researchers should align their research practices more closely with the needs of practitioners in external organizations. One important but under-researched strand of this debate focuses on the way in which ‘relevance’ is pu
EasyArchive is a vendor of an email archiving software solution. EasyArchive’s sales are not growing with the same speed as the market, which is forecasted to grow with up to 1000% within the next 5 years. EasyArchive’s direct sales force can expand but the company is also evaluating alternative marketing channels. The number of potential types of channels and the number of players in each channel
Transformation-based learning (TBL) is a machine learning method for sequential classification, invented by Eric Brill (1993, 1995). It is widely used within natural language processing (but surprisingly little in other areas). TBL is a simple yet flexible paradigm, which achieves competitive or even state-of-the-art performance in several areas and does not overtrain easily. It is especially suc
In this essay we have examined how social workers experience their positions as a public authority person in a society of democracy. As a public officer you have to follow rules and obey the law, which can be difficult if they don't agree with your personal opinion and values. In social work you work with people in a vulnerable situation and it may become extremely demanding to stand between t
Title: Creativity and blockings: Non-musicians? experiences of music making The purpose of this study was to investigate whether the ability of music-making can benefit from and/or be inhibited by extra-musical factors, such as one's own or other people's opinions, criticism, prejudice and values. An experiment was carried out, where 10 nonmusicians were instructed to solve a compositional
A real-time optical imaging system has been developed and commissioned at the European Spallation Source (ESS) to monitor the high-power proton beam at the tuning beam dump, and provide machine protection. The system employs chromium-doped alumina (Chromox) luminescent screens imaged by radiation-shielded optics and a CMOS camera. Real-time FPGA-based processing extracts beam size and position, de
Lignins are a polymeric, renewable resource with remarkable structural diversity. Research is being conducted into the valorisation of lignins into value-added products. The absence of experimental libraries, in particular for process-modified oligomers, hampers analytical feedback to these valorisation efforts. Stochastic methods for generating libraries in-silico have been proposed, but were not
The laser wake-field accelerator (LWFA) traditionally produces high brightness, quasi-monoenergetic electron beams with Gaussian-like spatial and angular distributions. In the present work we investigate the generation of ultra-relativistic beams with ring-like structures in the blowout regime of the LWFA using a dual stage accelerator. A density down-ramp triggers injection after the first stage
Metal microstructured optical elements for grating-based X-ray phase-contrast interferometry were fabricated by using an innovative approach of microcasting: hot embossing technology with low melting temperature (280 °C) metal alloy foils and silicon etched templates. A gold-tin alloy (80 wt% Au/20 wt% Sn) was used to cast micro-gratings with pitch sizes in the range of 2 to20 μm and depth of the
Portal hypertension (PH) is a major complication of chronic liver disease, often leading to serious clinical consequences such as variceal bleeding, ascites, and splenomegaly. The current gold standard for PH diagnosis, namely, hepatic venous pressure gradient measurement, is invasive and not widely available. Transient elastography has emerged as a non-invasive alternative for assessing liver sti
Introduction: South Africa has one of the highest incidence rates of notified tuberculosis (TB) in the world. Achieving TB control requires strengthening treatment and support services. The implementation of differentiated delivery models can be used to improve service quality and enhance retention in care. This study aimed to identify treatment and support delivery preferences among people on TB
This poster explores sustainable water treatment using membrane technologies from a joint South Africa–Sweden perspective. While membrane processes such as MF, UF, NF, RO, and MBRs play a critical role in achieving Sustainable Development Goal 6, their adoption remains uneven due to high capital and operational costs. In South Africa, membrane use is still rare, with only a few MBR installations a
