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BACKGROUND: Patients with chronic respiratory failure treated with long-term oxygen therapy (LTOT) often have severe breathlessness, impaired exercise performance, and high but variable mortality that is difficult to predict. We aimed to evaluate breathlessness and exercise performance upon starting LTOT as predictors of overall and short-term mortality.METHODS: This was a longitudinal, population
Background: The purpose of this paper is to explore the underlying challenges in the telehealth environment in India and Pakistan that impede the delivery of high-quality images between a patient and health care professional.Method: An exploratory study was conducted among healthcare professionals in India and Pakistan to assess their perceptions regarding image quality, which is used for the diag
In this paper, I briefly present my doctoral thesis research proposal. Recognizing that information has long been an important asset for any organization, I wish to explore in depth the management and use of information in contemporary information-intensive organizations such as academic libraries. Additionally, this research proposal emerges out of recognition that the academic library is a dynam
Objective: The purpose of the study was to examine associations between self-esteem and symptoms of anxiety and depression among young adults who lost a parent to cancer. Methods: Older adolescents and young adults, aged 16 to 28 years, who had lost their parent to cancer and had accepted an invitation to join a support group, completed a questionnaire 5 to 8 months after the loss and a similar qu
Breathlessness is common in the general population. Existing data were obtained primarily with the uni-dimensional modified Medical Research Council breathlessness scale (mMRC) that does not assess intensities of unpleasantness nor physical, emotional and affective dimensions. The aim of this research was to determine the prevalence and intensity of these dimensions of breathlessness in elderly ma
Structural Health Monitoring (SHM) plays a vital role in maintaining the integrity of structures by providing continuous information about damage or anomalies. Vibration-based SHM, which focuses on the dynamic behavior of structures, offers insights into structural conditions through changes in dynamic properties. Among SHM approaches, damage localization is crucial for pinpointing the geometric l
Structural maintenance of chromosome (SMC) complexes organize and regulate genomes via DNA loop extrusion. During this process, the complexes increase the loop size by reeling in DNA from one or both sides of the loop. The factors governing this symmetry remain unclear. Here, we combine single-molecule analysis and molecular dynamic simulations to investigate the symmetry of loop extrusion of vari
Purpose of review Breathlessness is a common, distressing and limiting symptom in people with advanced disease, but is challenging to assess as the symptom intensity depends on the level of exertion (symptom stimulus) during the assessment. This review outlines how to use recently developed normative reference equations to evaluate breathlessness responses, accounting for level of exertion, for va
AbstractThis study investigates the establishment and significance of United Nations (UN) Day, October 24, in Swedish primary and secondary schools from 1948 to 1963. This article conceptualizes the celebrations as knowledge rituals, educative events that foreground practices of knowledge-sharing, reinforcing social bonds and enhancing collective understanding. UN Day knowledge rituals combined ceThis study investigates the establishment and significance of United Nations (UN) Day, October 24, in Swedish primary and secondary schools from 1948 to 1963.This article conceptualizes the celebrations as knowledge rituals, educative events that foreground practices of knowledge-sharing, reinforcing social bonds and enhancing collective understanding. UN Day knowledge rituals combined ceremonial
BACKGROUND: Long-term oxygen therapy (LTOT) improves survival in patients with chronic severe resting hypoxaemia, but effects on hospitalisation are unknown. This study evaluated the potential impact of starting LTOT on acute exacerbation and hospital burden in patients with chronic obstructive pulmonary disease (COPD), interstitial lung disease (ILD) and pulmonary hypertension (PH).METHODS: Longi
Airborne depth sounding lidar has proven to be a valuable sensor for rapid and accurate sounding of shallow areas. The received lidar pulse echo contains information of the sea floor depth, but also other data can be extracted. We currently perform work on bottom classification and water turbidity estimation based on lidar data. In this paper we present the theoretical background and experimental
BACKGROUND: Falls are common among older persons and can have a major impact on their lives. Wearable sensors used in free-living conditions (moving naturally in one's daily living environment) can be used to predict falls and fall risks. To understand if using the wearable sensors is an acceptable way for older persons to be screened for fall risks, it is important to have knowledge of older pers
Traumatic brain injury (TBI) leads to intracerebral inflammation involving resident microglial cells and astrocytes as well as invading peripheral dendritic cells (DCs), monocytes, and neutrophils. However, the profile of immune blood cells activated by TBI remains poorly defined. Several animal models showing invasion of circulating classical dendritic cells type 2 (cDC2s) to the traumatically in
Introduction: Vitamin D deficiency has previously been shown to be associated with cancer-related fatigue. If vitamin D deficiency affects fatigue in frail elderly has not been studied before. The aim of this study was to investigate associations between vitamin D, fatigue, frailty, and sarcopenia in frail elderly with cancer (FEC) and without cancer (FE) in comparison with healthy controls. Metho
This study investigates the first Climate City Contracts (CCCs) in Sweden and consequently Europe. To do so, it evaluates the content of the Swedish CCCs against a framework for best practice deep decarbonisation plans.
This study explores the global trend of cities declaring a climate emergency. To do so, it delves into the experiences in Sweden with climate emergency statements and if or how cities are adopting a ”climate emergency mode”.
Background: Small-bore chest drains are now the most common drains for treating pleural effusion (PE), but knowledge on complications is limited especially in malignant PE and empyema. We aimed to evaluate rate of complications of ultrasound guided small bore chest drains [6–10 French (F)] by PE etiology. Methods: Retrospective cohort study of 484 chest drains inserted in 330 adults in a Swedish d
Phase contrast micro-CT is a powerful technique allowing imaging of soft tissue at synchrotrons or using lab- oratory sources. The use of contrast agents is a useful approach when imaging vascular structures. However, common x-ray contrast agents typically rely on heavy metals to increase absorption, which may affect the phase contrast and cause artifacts in the reconstructed volumes. Thus, utiliz
