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Histopathology Analysis of sentinel node biopsy - a single-institution experience supporting the use of serial sectioning and immunohistochemistry for detection of micrometastases by comparing four different histopathological laboratory protocols Aims: Detecting micrometastases (>0.2 and ≤2 mm/>200 cells) and isolated tumour cells (ITCs; ≤0.2 mm/<200 cells) is important for staging of breast canc
Clofarabine has been shown to effectively induce remission in children with refractory leukemia. We conducted a prospective trial (clinicval.trials.gov NCT01025778) to explore the use of clofarabine-based chemotherapy as a bridge-to-transplant approach. Children with refractory acute leukemia were enrolled to receive two induction courses of clofarabine, etoposide, and cyclophosphamide (CloEC). Re
This is the final report of the project PPP-Future, which studied the impacts of the Lamu Port Project on the Marine Cultural Heritage of the local and indigenous communities, as well as the impacts on their human rights.
A search for supersymmetry in events with large missing transverse momentum, jets, and at least one hadronically decaying tau lepton has been performed using 3.2 fb-1 of proton–proton collision data at s=13TeV recorded by the ATLAS detector at the Large Hadron Collider in 2015. Two exclusive final states are considered, with either exactly one or at least two tau leptons. No excess over the Standa
Peripheral artery disease affects >200 million people worldwide and is associated with significant limb and cardiovascular morbidity and mortality. Limb revascularization is recommended to improve function and quality of life for symptomatic patients with peripheral artery disease with intermittent claudication who have not responded to medical treatment. For patients with critical limb ischemia,
A search for direct top squark pair production resulting in events with either a same-flavour opposite-sign dilepton pair with invariant mass compatible with a Z boson or a pair of jets compatible with a Standard Model (SM) Higgs boson (h) is presented. Requirements on the missing transverse momentum, together with additional selections on leptons, jets, jets identified as originating from b-quark
Stress-related disorders are a frequent cause for sick leave, with consequences such as great distress and adverse economic effects for the affected person and substantial costs for society. Identifying effective interventions that facilitate return to work is thus important. The aim of this study was to evaluate the effectiveness of the 16-week Redesigning Daily Occupations program as a work reha
Evidence for an involvement of striatal D1 receptors in levodopa-induced dyskinesia has been presented whereas the contribution of striatal D2 receptors remains controversial. In addition, whether D1 and D2 receptors located in the substantia nigra reticulata shape the response to levodopa remains unknown. We therefore used dual probe microdialysis to unravel the impact of striatal and nigral D1 o
Parental Estimation of Their Child’s Increased Type 1 Diabetes Risk During the First 2 Years of Participation in an International Observational Study Journal of Empirical Research on Human Research Ethics 2016, Vol. 11(2) 106–114 © The Author(s) 2016 Reprints and permissions: sagepub.com/journalsPermissions.nav DOI: 10.1177/1556264616648589 jre.sagepub.com Research Concerning Young People Type 1 d
https://www.teddy.lu.se/sites/teddy.lu.se/files/09092016_679_56_mp67_swartling_jerhre_2016.pdf - 2026-07-25
The system that regulates insulin secretion from beta-cells in the islet of Langerhans has a capsaicin-sensitive inhibitory component. As calcitonin gene-related peptide (CGRP)-expressing primary sensory fibers innervate the islets, and a major proportion of the CGRP-containing primary sensory neurons is sensitive to capsaicin, the islet-innervating sensory fibers may represent the capsaicin-sensi
A search for electroweak production of supersymmetric particles is performed in two-lepton and three-lepton final states using recursive jigsaw reconstruction, a technique that assigns reconstructed objects to the most probable hemispheres of the decay trees, allowing one to construct tailored kinematic variables to separate the signal and background. The search uses data collected in 2015 and 201
Popular Abstract in Swedish Under 9 år (1989-1997) studerades individuellt märkta mindre hackspettar i ett undersökningsområde i södra Smålands ädellövskogar. De flesta studierna gjordes i 17 potentiella revir, vilka undersöktes årligen. Följningar av hackspettar försedda med radiosändare visade att fåglarna rörde sig inom ett, i medeltal, 742 ha stort hemområde under vintern. Under häckningstideOver 9 years, 116 breeding attempts made by individually marked lesser spotted woodpeckers (Dendrocopos minor) were followed in a study area in southern Sweden. The home-range area decreased from on average 742 ha in winter to a defended territory of 103 ha prior to breeding and 43 ha during nesting. The annual timing of the breeding varied between years but was each year synchronized with the bu
Protein kinase B (PKB)/Akt has been strongly implicated in the insulin-dependent stimulation of GLUT4 translocation and glucose transport in skeletal muscle and fat cells. Recently an allosteric inhibitor of PKB (Akti) that selectively targets PKB alpha and -beta was reported, but as yet its precise mechanism of action or ability to suppress key insulin-regulated events such as glucose and amino a
These practice guidelines for the biological treatment of substance use disorders were developed by an international Task Force of the World Federation of Societies of Biological Psychiatry (WFSBP). The goal during the development of these guidelines was to review systematically all available evidence pertaining to the treatment of substance use disorders, and to reach a consensus on a series of p
Head-and-neck tumors are often situated at an air-tissue interface what may result in an underdosage of part of the tumor in radiotherapy treatments using megavoltage photons. especially for small fields. In addition to effects of transient electronic disequilibrium, for these small fields, an increased lateral electron range in air will result in an important extra reduction of the central axis (
Popular Abstract in Swedish Delaktighet i biståndsbedömning av äldre personer inför kommunalt bistånd. Äldre personers, familjemedlemmars och biståndsbedömares upplevelser. Den äldre generationen förväntas snabbt öka i Sverige och i övriga Europa under de kommande årtiondena. De äldres vårdbehov kommer att öka och därmed förväntas svårigheter att ombesörja tillräcklig kommunal vård och omsorg. ÅlAim: The overall aim of this thesis was to illuminate older persons' experience of becoming in need of public home help and their family members' experience of this situation. Further, the aim was to illuminate experiences of participation in the needs assessment process of older people and influence on decisions about public home help from the perspective of older needs-assessed persons, their fa
