Search results

Aims: In the present study, we aimed to evaluate the performance of machine learning (ML) models for identification of acute myocardial infarction (AMI) or death within 30 days among emergency department (ED) chest pain patients. Methods and results: Using data from 9519 consecutive ED chest pain patients, we created ML models based on logistic regression or artificial neural networks. Model input

Cardiovascular magnetic resonance (CMR) can accurately measure left ventricular (LV) mass, and several measures related to LV wall thickness exist. We hypothesized that prognosis can be used to select an optimal measure of wall thickness for characterizing LV hypertrophy. Subjects having undergone CMR were studied (cardiac patients, n = 2543; healthy volunteers, n = 100). A new measure, global wal

Biodiversity is in decline due to human-induced pressures on ecosystems around the world. To be able to counteract this alarming trend, it is paramount to closely monitor biodiversity at global scales. Because this is practically impossible with traditional methods, the last decade has seen a strong push for new solutions. In aquatic ecosystems, the monitoring of species from environmental DNA (eD

This contribution analyses the evolution of public support for the single European currency, the euro, from 1990 to 2014 for a 12-country sample of the euro area (EA-12), focusing on the most recent period of the financial and sovereign debt crisis, starting in 2008. We find that citizens’ support for the euro on average was marginally reduced during the first six years of the crisis, and that sup

This chapter contains an outline of the Swedish social security system with a focus on sickness benefits in the social security and unemployment insurance. The Swedish legislator’s ambition has been to create parity between different forms of employment as well as between those who are self-employed and those who operate in different company structures. Legislative amendments in this area have mai

The extent and composition of the immune response in a breast cancer is one important prognostic factor for the disease. The aim of the current work was to refine the analysis of the humoral component of an immune response in breast tumors by quantifying mRNA expression of different immunoglobulin classes and study their association with prognosis. We used RNA-Seq data from two local population-ba

PurposeIn early breast cancer (BC), five conventional biomarkers—estrogen receptor (ER), progesterone receptor (PgR), human epidermal growth factor receptor 2 (HER2), Ki67, and Nottingham histologic grade (NHG)—are used to determine prognosis and treatment. We aimed to develop classifiers for these biomarkers that were based on tumor mRNA sequencing (RNA-seq), compare classification performance, a

The radiocarbon concentration of different atherosclerotic plaque fragments obtained from 20 patients in Portugal, operated in 2000-2001, has been measured in order to define the year of plaque formation. A difference of 1.8-15 yr was observed, with the mean and median both 9 yr, between the bomb-pulse date estimated with the CALIBomb software and the operation date. Stable isotope (delta C-13 and

Shrunken pore syndrome (SPS) is defined by a cystatin C-based estimation of glomerular filtration rate (eGFRCYS) being less than 60% or 70% of a creatinine-based GFR estimation (eGFRCR) in the absence of extrarenal influences on cystatin C or creatinine concentrations. SPS has been associated with a substantial increase in mortality or morbidity in all investigated populations. However, in these s

Languages differ in how events are described, but little is known about how semantics interacts with online event processing. This study targets this question examining placement events in Swedish. Swedish has three obligatory placement verbs for events where objects have support from below: sätta ’set’, ställa ’stand’, and lägga ’lay’. Swedish lacks a superordinate general term like English put (

Syfte är att belysa posthumanistiska perspektiv i pedagogisk forskning. Vi vill med vidga förståelsen för den förskjutning som de senaste åren har skett från poststrukturalism till posthumanism. Det har bl. a inneburit att forskningsintresset flyttas från språk till materia och andra icke-mänskliga företeelser. Vad innebär denna ontologiska vändning för synen på språket? Hur tänker vi kring subjek

This study investigated the feasibility of targeting the free, unbound forms of prostate-specific antigen (fPSA) for in vivo imaging of prostate adenocarcinomas (PCa), as PSA is produced and secreted at abundance during every clinical stage and grade of PCa, including castration-resistant disease. We injected (125)I-labeled monoclonal antibody PSA30 (specific for an epitope uniquely accessible on

Several immunodeficiency-related genes are known and a numb er of disease causing mutations have been identified. Immunodeficiency related mutation information have been collected into IDbases. We are currently maintaining 15 registries, which are available at http://www.uta.fi/imt/bioinfo/. The databases are available for the following disorders: adenosine deaminase, CD3 epsilon, CD3 gamma, JAK3,

The differences in fuel consumption and exhaust emissions for residential areas with different street network designs were investigated. Five areas with three different designs, including a traditional grid network and designs feeding the traffic in from a surrounding street and from a centrally located street, were considered. Differences in total fuel consumption and amount of exhaust emissions

This paper presents a numerical investigation of heat transfer from impinging swirling jets. Various turbulence models are used. Comparison with experimental data is provided. Generally the V2F model was found to perform better than other models but for small nozzle to plate distances it was hard to maintain good accuracy. The difference in performance, in terms of the Nusselt number distribution

An important component of the aircraft generated noise, especially ahead of it, is the fan noise created by the high velocity variation near the blades and the interaction of the rotating fan with the fluid. In order to predict the sound, the method used involves the acoustical analogy developed by Ffowcs Williams and Hawkings. Computation of the flow field is performed in the incompressible LES f

Designers’ work sometimes originates from a simplified view of human demands and needs, which may result in furniture that does not fulfill the user requirements. If we consider old people as one group with fairly similar needs and demands rather than have realistic images of old people as a heterogeneous group there is a tendency that it will result in misguided efforts to design for wellbeing. T