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Partitioned polygenic scores (pPS) have been developed to capture pathophysiologic processes underlying type 2 diabetes (T2D). We investigated the association of T2D pPS with diabetes-related traits and T2D incidence in the Diabetes Prevention Program. We generated five T2D pPS (b-cell, proinsulin, liver/lipid, obesity, lipodystrophy) in 2,647 participants randomized to intensive lifestyle, metfor

Second-order phase transitions appear as a divergence in one of the linear response functions. For a system of correlated electrons, the relevant divergent response can and does involve many-particle observables, most famously the double occupancy. Generally, evaluating the linear response function of many-particle observables requires a many-particle generalization of the Bethe-Salpeter equation.

Mutations in the CFTR gene result in impaired host defense during cystic fibrosis (CF), where Pseudomonas aeruginosa becomes a key pathogen. We investigated the expression pattern of the antibacterial growth factor midkine in CF and possible interference with its activity by the altered airway microenvironment. High midkine expression was found in CF lung tissue compared with controls, involving e

BACKGROUND: Axillary staging via sentinel lymph node biopsy (SLNB) is performed for clinically node-negative (N0) breast cancer patients. The Skåne University Hospital (SUS) nomogram was developed to assess the possibility of omitting SLNB for patients with a low risk of nodal metastasis. Area under the receiver operating characteristic curve (AUC) was 0.74. The aim was to validate the SUS nomogra

Background: Correct preoperative estimation of the malignant extent is crucial for optimal planning of breast cancer surgery. The sensitivity of mammography is lower in dense breasts, and additional imaging techniques are sometimes warranted. Contrast-enhanced mammography (CEM) has shown similar sensitivity and in some cases better specificity, than magnetic resonance imaging (MRI) in small, obser

The costly and complex needs for children with long-term illness are challenging. Safe eHealth communication is warranted to facilitate health improvement and care services. This mixed-methods study aimed to describe parents’ usage and experiences of communicating with professionals during hospital-to-home-transition after their child’s preterm birth or surgery for col-orectal malformations, using

Studies have shown positive health outcomes from shared reading (SR) for various patient groups. In this article, we explore whether this applies to doctors as well by studying the dynamics of SR sessions and a subsequent participant focus group. Four SR sessions, with one short story and one or two poems each, were held with medical interns working at Skåne University Hospital, Sweden. A reflexiv

Background and objective: Prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) is an evolving diagnostic tool for prostate cancer. There is a need to harmonise existing guidelines and reporting recommendations for PSMA PET/CT. The Standardised PSMA PET/CT Analysis and Reporting Consensus (SPARC) project aims to consolidate classifications and recommen

Correlated electron physics is intrinsically a multiscale problem, since high-energy electronic states screen the interactions between the correlated electrons close to the Fermi level, thereby reducing the magnitude of the interaction strength and dramatically shortening its range. Thus the handling of screening is an essential ingredient in the first-principles modeling of correlated electron sy

By combining ab initio downfolding with cluster dynamical mean-field theory, we study the degree of correlations in monolayer, bilayer, and bulk breathing-mode kagome van der Waals materials Nb3(F, Cl, Br, I)8. Our new material-specific many-body model library shows that in low-temperature bulk structures the Coulomb correlation strength steadily increases from I to Br, Cl, and F, allowing us to i

IntroductionAlthough Chronic Obstructive Pulmonary Disease (COPD) is generally considered a progressive condition with limited reversibility, recent data suggests potential for lung function improvement with exercise. Mechanistic insights into exercise-induced benefits remain limited, but in vitro models offer promise for understanding cellular and molecular changes. This study aims to elucidate t

BACKGROUND AND OBJECTIVE: The treatment landscape for metastatic hormone-sensitive prostate cancer (mHSPC) is evolving rapidly. Real-world data (RWD) are essential to understand actual treatment use and outcomes. This study aimed to describe treatment trajectories and clinical outcomes in a large, multicenter RWD cohort under the PIONEER project. METHODS: Eight European and US databases (2016-2020

Titel: Spel på planen och i redovisningen Seminariedatum: 2026-01-14 Kurs: FEKH69, Examensarbete i redovisning på kandidatnivå, 15 HP Författare: Elias Haglund, Calle Johansson Lundqvist, Zebastian Öhlund Handledare: Johan Dergård Nyckelord: Profit and sustainability rules; Redovisningseffekter; Beteendeeffekter; Reglering Forskningsfrågor: Hur har PSR påverkat Premier League klubbarnas externa Title: Play on the pitch and in the accounts Seminar date: 2026-01-14 Course: FEKH69, Bachelor degree project in Accounting, undergraduate Level, 15 ECTS-Credits Authors: Elias Haglund, Calle Johansson Lundqvist, Zebastian Öhlund Advisor: Johan Dergård Key words: Profit and sustainability rules; Accounting effects; Behavioral effects; Regulations Research questions: How has PSR affected Premier Le

The development of acid-stable, non-precious catalysts for the oxygen evolution reaction (OER) remains a critical challenge for proton exchange membrane water electrolyzers (PEMWEs). While Co3O4 shows promising OER activity, its rapid dissolution in acidic media severely limits practical application. Here, we design a self-adaptive protection strategy by depositing ZrN coatings on Co3O4 precursor

Carbon Black (CB), graphene, and nanodiamond are distinct carbonaceous insoluble nanoparticles. Reactive Oxygen Species (ROS) associated with these particles play a significant role in both in vivo and in vitro toxicity evaluations. Accurate assessment of ROS activity is relevant for toxicity screening and in ensuring safe working environments as well as guiding the innovation by safe-and-sustaina

Background: Adverse events induced by intravesical bacillus Calmette-Guérin (BCG) to treat high-grade non–muscle-invasive bladder cancer (NMIBC) often lead to treatment discontinuation. The EAU-RF NIMBUS trial found a reduced number of standard-dose BCG instillations to be inferior with the standard regimen. Nonetheless, it remains important to evaluate whether patients in the reduced BCG treatmen

Background: Whether disease burden in patients with metastatic castration-sensitive prostate cancer (mCSPC) predicts treatment outcomes is unknown. We assessed apalutamide treatment effect in TITAN patients with mCSPC by disease volume, metastasis number and timing of metastasis presentation. Methods: These protocol-defined and post hoc analyses of the phase III randomised TITAN study evaluated cl

Projektplan-Organisationsutveckling mot färre och större enheter vid Samhällsvetenskapliga fakulteten Sida 1 av 17 PROJEKTPLAN Diarienummer STYR 2025/1956 Fastställd 2023-09-21(STYR 2023/1630). Reviderad 2024-09-19 (STYR 2024/1927) Reviderad 2025-09-25 (STYR 2025/1956) Organisationsutveckling mot färre och större enheter vid Samhällsvetenskapliga fakulteten Uppdragsgivare: Dekan, Agnes Andersson P

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2025-10/Projektplan_organisationsprojekt_25-09-25_beslut_sv%5B34%5D.pdf - 2026-05-25

Inom Lunds universitet finns fem parkeringszoner: Budgetzon, zon A, zon B, zon C och zon MV. Vid infarten till alla parkeringsplatser finns tavlor som visar vilken zon parkeringen tillhör. Allmänna anvisningar för parkeringAvgift ska betalas hela året, dygnet runt, inom alla zoner.Innehav av fysiska och digitala parkeringstillstånd eller biljett innebär rätt att parkera ett fordon inom angiven zon

https://www.medarbetarwebben.lu.se/stod-och-verktyg/lokaler-och-parkering/parkering/villkor-parkering - 2026-05-25