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This In Memoriam presents the life of Simone Veil, an influential French politician, remembered for a law that made abortion legal in 1974. Simone Veil's contribution to the rights of women is featured as an instance of parrhesia (Foucault, 2011) that was able to establish a new regime of truth about the body, sexuality, and reproductive capacities of French women.
Background: In recent years, our group has developed electro-optical remote sensing methods for the monitoring and classification of aerofauna. These methods include active lidar methods and passive, so-called dark-field methods that measure scattered sunlight. In comparison with satellite- and airborne remote sensing, our methods offer a spatiotemporal resolution several orders of magnitude highe
Tumors are phenotypically heterogeneous and include subpopulations of cancer cells with stemlike properties. The natural product salinomycin, a K+-selective ionophore, was recently found to exert selectivity against such cancer stem cells. This selective effect is thought to be due to inhibition of the Wnt signaling pathway, but the mechanistic basis remains unclear. Here, we develop a functionall
Laminin α2 chain-deficient muscular dystrophy, or LAMA2-CMD, is a very severe disease caused by mutations in the LAMA2 gene. Skeletal muscle is the most affected tissue, with patients presenting symptoms such as hypotonia at birth, joint contractures and progressive muscle wasting. Changes in the central nervous system include white matter abnormalities, delayed motor milestones and compromised ac
Extracting microanatomical information beyond the image resolution of MRI would provide valuable tools for diagnostics and neuroscientific research. A number of mathematical models already suggest microstructural interpretations of diffusion MRI (dMRI) data. Examples of such microstructural features could be cell bodies and neurites, e.g. the axon's diameter or their orientational distribution for
We present high-power Yb:YAG lasers combined with nonlinear pulse compression in multi-pass cells. We show that these are suitable for integration in FEL facilities in terms of pulse stability, jitter, temporal contrast and intra-burst behaviour.
A continuous rotary membrane emulsification (cRME) system, allowing the decoupling of droplet generation from continuous phase (CP) flowrate, is presented here for the first time. The decoupling results in higher productivity and greater control compared to traditional crossflow and rotational membrane emulsification processes. A design of experiment (DoE) investigated the influence on droplet for
Amphiphilic polyoxometalate (POM) surfactants were prepared by covalently grafting double hydrophobic tails with chain lengths C12H25, C14H29, C16H33 or C18H37 onto the lacunary Wells-Dawson {P2W17O61} headgroup. The critical micelle concentrations (CMCs) of these novel surfactants in aqueous solutions were determined by conductivity, and micelle formation was studied by small angle neutron scatte
Background: The demographic shift is fast becoming a global challenge. Populations ageing rapidly is widely seen as one of the most powerful transformative forces affecting society over the next four decades.Due to the demographic challenge in most countries it is important to consider making working life sustainable. It is obvious that the main factor that distinguishes senior workers from other
An inspiring conversation between Sister Jayanti, European Director of Brahma Kumaris, and Professor Christine Wamsler, Director of the Contemplative Sustainable Futures Program.
Leptons with essentially the same properties apart from their mass are grouped into three families (or flavours). The number of leptons of each flavour is conserved in interactions, but this is not imposed by fundamental principles. Since the formulation of the standard model of particle physics, the observation of flavour oscillations among neutrinos has shown that lepton flavour is not conserved
The Storage Location Assignment Problem (SLAP) is of primary significance to warehouse operations sincethe cost of order-picking is strongly related to where and how far vehicles have to travel. Unfortunately, ageneralized model of the SLAP, including various warehouse layouts, order-picking methodologies andconstraints, poses a highly intractable problem. Proposed optimization methods for the SLA
Background: [18F]PSMA-1007 is a promising tracer for integrated positron emission tomography and computed tomography (PET/CT). Objective: Our aim was to assess the diagnostic accuracy of [18F]PSMA-1007 PET/CT for primary staging of lymph node metastasis before robotic-assisted laparoscopy (RALP) with extended lymph node dissection (ePLND). Design, Setting and Participants: The study was a retrospe
Arctic and subarctic areas have experienced a rapid warming and substantial increases in precipitation in recent decades. The frequency and intensity of some extreme events, such as fires, winter warming events, extreme rainfall, and droughts, has also increased. These climatic changes and other anthropogenic factors have caused profound changes in arctic and subarctic ecosystems with important im
Autoimmune murine disease models are vital tools for identifying novel targets and finding better treatments for human diseases. Complete Freund’s adjuvant is commonly used to induce disease in autoimmune models, and the quality of the adjuvant/autoantigen emulsion is of critical importance in determining reproducibility. We have established an emulsification method using a standard homogenizer an
The COVID-19 accelerated shift towards hybrid workspaces places major pressure onworkplace communities and culture. This study explores the emergence of a collaborative academic workspace, which is still in the real estate development phase. The aim is to establish preconditions for community building, and the relationship between the community and the physical space. The study employs a qualitati
The use of biofilms to improve the removal of organic micropollutants in waste¬water treatment plants (WWTPs) has been investigated. The work is divided into two parts. In the first part, the use of biofilms for the biological degradation of micro¬pollutants was investigated. In the second part, micropollutant removal was investigated with biofilm processes in combination with ozonation or activat
Removal of carbon dioxide from the atmosphere will be required over the next decades to achieve the Paris Agreement goal of limiting global warming to well below 2°C aiming at not exceeding 1.5°C. Technological and ecosystem-based options are considered for generating negative emissions through carbon dioxide removal (CDR) and several nations have already included these in their Long-Term Low Gree
The Memorial Sloan Kettering Cancer Center (MSKCC) recommendations on prostate cancer screening were developed in response to three limitations of previous screening guidelines: insufficient evidence base, failure to link screening with treatment, and lack of risk stratification. The objective of the recommendations is to provide a schema for prostate cancer screening that maximizes the benefits,
