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Evacuation models generally include the use of distributions or probabilistic variables to simulate the variability of possible human behaviours. A single model setup of the same evacuation scenario may therefore produce a distribution of different occupant-evacuation time curves in the case of the use of a random sampling method. This creates an additional component of uncertainty caused by the i

The mechanisms of neuronal cell death are still only poorly understood, which has hindered the advancement of therapies for many currently untreatable neurodegenerative diseases. This calls for the development of new methods which reveal critical molecular mechanisms of the celldeath machinery with both high sensitivity and cellular resolution. Using animal models for hereditary neurodegeneration

The problem of integrating the Camassa-Holm equation leads to the scattering and inverse scattering problem for the Sturm-Liouville equation -u '' + 1/4 u = lambda wu, where w is a weight function which may change sign but where the left-hand side gives rise to a positive quadratic form so that one is led to a left-definite spectral problem. In this paper the spectral theory and a generalized Four

Anti-idiotypic antibodies (anti-Id) to autoantibodies are present in several autoimmune diseases and are hypothesized to have regulatory function. Recently we reported the presence of anti-Id to a major type 1 diabetes-associated autoantibody (CAD65Ab) in sera of healthy individuals. Our current assay for the detection of GAD65Ab-specific anti-Id requires the initial removal of anti-Id from the se

The aim of this study is to extend the traffic safety assessment concept to also include normal road user behaviour, thus not only exceptional behaviours such as accidents and serious conflicts. The goal is to provide a framework for a more thorough description and analysis of safety related road user behaviour in order to better understand the traffic safety processes. The traffic safety process

In this perspective article, we provide recommendations for strengthening the policy framework for protecting the Baltic Sea from agricultural nutrient pollution. The most striking weakness is the lax implementation of prescribed abatement measures, particularly concerning manure management, in most countries. Institutions of the EU should also be leveraged for achieving Baltic Sea Action Plan (BS

Infectious diseases are an existential health threat, potentiated by emerging and re-emerging viruses and increasing bacterial antibiotic resistance. Targeted treatment of infectious diseases re-quires precision diagnostics, especially in cases where broad-range therapeutics such as antibiotics fail. There is thus an increasing need for new approaches to develop sensitive and specific in vitro dia

The time-dependent traveling salesman problem (TDTSP) is a variant of TSP with time-dependent edge costs. We study some restrictions of TDTSP where the number of edge cost changes are limited. We find competitive ratios for online versions of TDTSP. From these we derive polynomial time approximation algorithms for graphs with edge costs one and two. In addition, we present an approximation algorit

Background: Electrocardiogram-derived grades of ischemia at the time of patient presentation with acute myocardial infarction have proved useful in predicting the salvageability by reperfusion therapy, final infarct size, severity of left ventricular dysfunction, and short- and long-term prognosis. Subjects and Methods: The Sclarovsky-Birnbaum Ischemia Grading System based on the relation between

This is the protocol for a review and there is no abstract. The objectives are as follows: To assess whether heparin treatment (both UFH and LMWH) in preterm and term newborn infants with diagnosed thrombosis reduces the rate of mortality and morbidity. The intervention will be compared to placebo or no treatment. In addition, the safety of heparin therapy (both UFH and LMWH) will be assessed for

Mankind has faced a huge increase in severe natural and man-made disasters worldwide in the last few years. Emergency responders on a strategic, tactical, and operational level can be assisted by decision support systems (DSS) to enhance disaster preparedness, response, and recovery. Policy makers are in need of an advanced, resilient and integrated incident command and control systems for emergen

The use of interactive visualization techniques in Digital Humanities research can be a useful addition when traditional automated machine learning techniques face difficulties, as is often the case with the exploration of large volumes of dynamic—and in many cases, noisy and conflicting—textual data from social media. Recently, the field of stance analysis has been moving from a predominantly bin

Avhandlingen undersöker betydelsen och funktionen av tårar i romersk politisk kultur under republiken och tidig kejsartid i olika historiska sammanhang, huvudsakligen sorg, tårar och i olika politiska sammanhang där auktoritet, makt och underkastelse utövades eller iscensattes. Detta görs genom studier av hur tårar skildras i olika genrer och författarskap i latinsk och grekisk litteratur. AllmäntThe thesis explores the meaning and function of tears in Roman political culture during the Republic and the Early Empire in various historical settings: mourning, the law court, and in different political contexts where power, authority, and subjection were expressed or exercised. This is carried through by reading representations of weeping in Greek and Latin literary works in different genres,

Multiple sclerosis is a neuroinflammatory degenerative disease, caused by activated immune cells infiltrating the CNS. The disease etiology involves both genetic and environmental factors. The mouse genetic locus, Eae27, linked to disease development in the experimental autoimmune encephalomyelitis (EAE) model for multiple sclerosis, was studied in order to identify contributing disease susceptibi

This paper studies the Front End of Eco-Innovation (FEEI), the initial phase of the eco-innovation process. Incorporating environmental concerns at the front-end of innovation is important, as product parameters are still flexible. This paper investigates the FEEI for 42 small and medium sized eco-innovators in the Netherlands by using a survey. The results show that SMEs embrace informal, systema

the research investigates how students perceive new approaches within language teaching. The background to the project is that students enrolled in the MA program in Middle Eastern Studies had to learn Arabic quickly, to be able to do field work and operate within Arabic speaking contexts. But beyond exploring new ways for students to pick up Arabic at a fast pace, Barhoum and Avery believe that t

The Öresund Region is a transnational region encompassing areas of southern Sweden (Skåne) and southeast Denmark (Sjælland and Hovedstaden). The Energi Öresund project seeks to offer strategic and cooperative energy planning for the region as a whole in order to meet the energy goals of Sweden, Denmark, and its constituent local municipalities. The project is funded by EU INTERREG IV, a European U

This paper presents the development as well as the architecture of a computer-aided dedicated fixture design system intended to support the design of lightweight (carbon fiber composite) grippers for a major truck company. Lightweight grippers were required due to the increasing production rates in the automotive industry. The current robotic equipment was facing diverse problems during transporta