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Elevated brain levels of apolipoprotein D (ApoD) correlate with improved neurological recovery after experimental stroke. Hence, a pharmacological induction of ApoD in the postischemic brain could be beneficial for recovery after stroke. Here we investigated the effect of Clozapine, a compound that increases the expression of ApoD, in two rat models of experimental stroke. Rats were subjected to p

Background: most fractures are preceded by falls.Objective: the aim of this study was to determine whether tests of physical performance are associated with fractures.Subjects: a total of 10,998 men aged 65 years or above were recruited.Methods: questionnaires evaluated falls sustained 12 months before administration of the grip strength test, the timed stand test, the six-metre walk test and the

Background:Familial nervous system cancers are rare and limited data on familial aspects are available particularly on site-specific tumours.Methods:Data from five Nordic countries were used to analyse familial risks of nervous system tumours. Standardised incidence ratios (SIRs) were calculated for offspring of affected relatives compared with offspring of non-affected relatives.Results:The total

Background. Allergy nurses are exposed to allergens and respiratory irritants, and there are no national guidelines addressing personnel safety when working with these agents. Objective. To investigate the prevalence of allergies, asthma, and hypersensitivity symptoms among allergy nurses and the use of protective equipment and measures when working with allergen concentrates and respiratory irrit

Systolic tissue Doppler measurements (s') have been used to measure the velocity in myocardial motion and are a valuable tool for evaluating the systolic function of the left and right ventricles. Digestion of food is known to significantly alter hemodynamics and may therefore affect s'. The effect of food intake on s' parameters has not yet been studied. We assessed whether s' is affected by food

OBJECTIVE: Cholecystectomy is the standard treatment for acute cholecystitis, but in high-risk patients with serious comorbidity and in patients of advanced age there is substantial morbidity and mortality associated with the intervention. In these selected patients, percutaneous cholecystostomy (PCS) is an alternative mode of management. The aim of the present study was to evaluate the outcome of

There is limited knowledge of knee laxity in the long term after a complete anterior cruciate ligament (ACL) tear treated without ACL reconstruction. The aim of this study was (1) to describe the clinical course of knee laxity after a complete ACL tear over 15 years, and (2) to study the association between knee laxity and meniscal injuries and the development of knee osteoarthritis (OA). We studi

Identifying the genetic variants that regulate fasting glucose concentrations may further our understanding of the pathogenesis of diabetes. We therefore investigated the association of fasting glucose levels with SNPs in 2 genome-wide scans including a total of 5,088 nondiabetic individuals from Finland and Sardinia. We found a significant association between the SNP rs563694 and fasting glucose

Neurogenesis in the adult mammalian brain is well studied, in the two main regions subventricular zone (SVZ) and subgranular zone (SGZ), under different physiological and pathological condition. Recent studies also revealed newly formed neurons in other parts of the brain including the hypothalamus. However, how robust neurogensis in this area is, is still unclear. In this study we used a novel re

Syftet med studien var att kvalitativt undersöka kvinnliga fotbollsspelares upplevelse av att nå elitnivå. Semistrukturerade intervjuer användes och totalt intervjuades tre deltagare. Intervjuerna analyserades med IPA (Interpretative Phenomenological Analysis) som metodologisk ansats. Totalt kunde fem teman urskiljas som centrala i upplevelsen av elitnivå: tankar och känslor kopplade till övergångThe purpose of this study was to qualitatively explore the experience of reaching the elite level for women in football. Semi-structured interviews were conducted with three participants. The interviews were analysed using Interpretative Phenomenological Analysis (IPA). In total, five themes emerged: thoughts and feelings associated with reaching the elite level, social support, gender identity, m

An inverse class D power amplifier and a class A power amplifier are designed at schematic level for 20 dBm power class and NB-IoT specification in 65 nm CMOS technology. A suitable switch mode supply modulator is also designed. Three different efficiency enhancement techniques namely EER, Hybrid EER and ET are studied and the suitable transmitters are simulated for each in Cadence Virtuoso. These

Diarrhoeal disease is the second leading cau- se of death in children under five years old, and is responsible for killing around 525 000 children every year. The spread of diseases is also a problem in our western society. Thanks to our developed me- dical infrastructure not to the extent as in de- veloping countries. Nevertheless the amount of work and school hours missed because of preven