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Apamin inhibits NO-induced relaxation of the spontaneous contractile activity of the myometrium from non-pregnant women

There is now considerable evidence for the involvement of K+ channels in nitric oxide (NO) induced relaxation of smooth muscles including the myometrium. In order to assess whether apamin-sensitive K+ channels play a role in NO - induced relaxation of the human uterus, we have studied the effect of specific blockers of these channels on the relaxation of myometrium from non-pregnant women. In vitr

Genetic Interactions in Eae2 Control Collagen-Induced Arthritis and the CD4+/CD8+ T Cell Ratio.

The Eae2 locus on mouse chromosome 15 controls the development of experimental autoimmune encephalomyelitis (EAE); however, in this study we show that it also controls collagen-induced arthritis (CIA). To find the smallest disease-controlling locus/loci within Eae2, we have studied development of CIA in 676 mice from a partially advanced intercross. Eae2 congenic mice were bred with mice congenic

LUM 4 2024

Förnyar lärarrollen med serier Gammal is hintar om solstormsfaror Kvinnorna som frontar LU Tilliten stukad VÄGEN FRAMÅT GÅR GENOM DIALOG LUNDS UNIVERSITETS MAGASIN | NR 4 | 2024 2 LUM NR 4 | 2024 LUM NR 4 | 2024 3 Inflammation har varit ledordet genom både Jenny Wigéns privata och yrkesmässiga liv. Hennes kro­ niska sjukdom och bandet till naturen banade väg för hennes senaste forsk­ ningsprojekt:

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2024-09/LUM%204%202024.pdf - 2026-05-20

Behavioral Rat Node Inftrastructure Report 2021

Microsoft Word - Behavioral Rat node_ inftrastructure report 2021.docx Multipark infrastructure report form 2021 In Vivo platform – rat node Malin Parmar 1. Short description of the infrastructure. The rat node of the MuPa Behavoural platform offers setups for motor and cognitive testing in animal models of neurodegenerative disease. It consists of multiple laboratories and equipment to do compreh

https://www.multipark.lu.se/sites/multipark.lu.se/files/2021-03/Behavioral%20Rat%20node_%20inftrastructure%20report%202021.pdf - 2026-05-20

Strategic Communication and Legitimacy in UN Peacekeeping: A Study of MONUSCO's Response to Goma Protests, DRC, in July 2022

This research explores the interplay between strategic communication and legitimacy in United Nations (UN) peacekeeping missions, focusing on the United Nations Stabilization Mission in the Democratic Republic of Congo (MONUSCO) and addresses the challenge of maintaining and establishing legitimacy through strategic communication during crises. The study specifically investigates the use of strate

System level cache prefetching algorithms for complex GPU workloads

Prefetching is a well known concept for CPUs but for GPUs it is fairly unexplored. The memory management of a GPU plays a crucial role in its performance, and cache prefetching has the potential to lower the overall latency. This thesis compares different types of prefetching methods for GPUs and remaking some CPU prefetchers to fit the GPU architecture. All these prefetchers were then put inside

Striking a balance: parties and government debt in an age of change. A comparative analysis of mainstream parties in advanced Western democracies

In recent decades, internal and external circumstances have increased the pressure on European states and the United States to act in response to such circumstances. The return of war on the European continent, shifting trade relations, climate change and its devasting effects on society and an aging population are all putting pressure on public finances. The aim of this study is to investigate th

Generational goal 2012-13 program actvities

Microsoft Word - Dokument3 Welcome to the Pufendorf’s Autumn 2012 series on Consumption, Environment, and the Generation Goal The Politics of the Generational Goals Friday, October 5, 14:15 - 15 at the Pufendorf Institute, Biskopsgatan 3 Seminar leader: Åsa Knaggård, Political Science The theme of this seminar is the Swedish generational goals for the environment. Many of the goals are very hard t

https://www.pi.lu.se/sites/pi.lu.se/files/generational_goal_2012-13_program_actvities.pdf - 2026-05-20

Intensity Modulated Radiotherapy Treatment Planning with OTP/TMS for Head&Neck Carcinomas in the ARTSCAN study

Cancer är en otrevlig sjukdom, som drabbar många människor. Man söker ständigt nya och bättre sätt att bota patienter eller åtminstone lindra sjukdomens framfart. Ett vanligt sätt att behandla cancer är med strålning. Strålningen kan bestå av sk fotoner. Fotoner är samma slags partiklar som t.ex. vanligt ljus. Skillnaden är att de fotoner som används vid strålbehandling av cancer har högre energi "Purpose: The aim of this study was to investigate whether inversely planned intensity modulated radiation therapy (IMRT), using the clinical radiotherapy equipment at hand in our department, renders any advantages regarding dose distribution over conventional radiotherapy for head and neck cancer patients in the ARTSCAN (Accelerated RadioTherapy of Squamous cell Carcinoma in the head And Nec

Women, Remittances, and Migration: A Critical Discourse Analysis of the Portrayal of Remitting Women in the Global Press

Research regarding remittances and development has long been plagued by a gender-neutral approach. Consideration is rarely given to why female migrants remit differently. Prior research suggests that female remitters may experience increased burdens and pressure to remit. Media effects theories dictate that the ways in which media is disseminated and consumed has societal impacts and consequences.

Simulator study on take-over request in partially automated vehicle using auditory and haptic modality

: Based on the recent progress on research and development on automated vehicles, mass production of partially autonomous driving vehicles is expected to be available in the 2020s. According to the SAE standard level 3, a takeover situation may occur where the vehicle driving party changes if autonomous driving is released for unavoidable reasons resulting from vehicle or system limitations. In th

A global database of soil microbial phospholipid fatty acids and enzyme activities

Soil microbes drive ecosystem function and play a critical role in how ecosystems respond to global change. Research surrounding soil microbial communities has rapidly increased in recent decades, and substantial data relating to phospholipid fatty acids (PLFAs) and potential enzyme activity have been collected and analysed. However, studies have mostly been restricted to local and regional scales

Digitally Delivered Exercise and Education Treatment Program for Low Back Pain : Longitudinal Observational Cohort Study

BACKGROUND: Exercise and education is recommended as first-line treatment by evidence-based, international guidelines for low back pain (LBP). Despite consensus regarding the treatment, there is a gap between guidelines and what is offered to patients. Digital LBP treatments are an emerging way of delivering first-line treatment.OBJECTIVE: The aim of this study is to evaluate outcomes after partic

Modeling Pan-Arctic Peatland Carbon Dynamics Under Alternative Warming Scenarios

Peatlands store large amounts of carbon in terrestrial ecosystems and they are vulnerable to recent warming. The ongoing warming may change their carbon sink capacity and could reduce their potential to sequester carbon. In this study, we simulated peatland carbon dynamics in distinct future climate conditions using the peatland-vegetation model (LPJ-GUESS). The study examined whether less pronoun

Enzymatic conversion of β-mannans: Analysing, evaluating and modifying transglycosylation properties of glycoside hydrolases

Retaining glycoside hydrolases are enzymes that catalyse the breakdown down of glycans through hydrolysis. Due to the double-replacement mechanism of the retaining glycoside hydrolases (GHs), which form an intermediate with part of the glycan covalently attached to the enzyme, some GHs are able to catalyse synthesis reactions called transglycosylation. In transglycosylation reactions a hydroxyl-co

The human melanoma proteome atlas-Defining the molecular pathology

The MM500 study is an initiative to map the protein levels in malignant melanoma tumor samples, focused on in-depth histopathology coupled to proteome characterization. The protein levels and localization were determined for a broad spectrum of diverse, surgically isolated melanoma tumors originating from multiple body locations. More than 15,500 proteoforms were identified by mass spectrometry, f

Who Still Gets Ligated? Reasons for Persistence of Surgical Ligation of the Patent Ductus Arteriosus Following Availability of Transcatheter Device Occlusion for Premature Neonates

(1) Background: To identify reasons for the persistence of surgical ligation of the patent ductus arteriosus (PDA) in premature infants after the 2019 Food and Drug Administration (FDA) approval of transcatheter device closure; (2) Methods: We performed a 10-year (2014–2023) single-institution retrospective study of premature infants (<37 weeks) and compared clinical characteristics and neonatal m

Omission of doxorubicin from the treatment of stage II-III, intermediate-risk Wilms' tumour (SIOP WT 2001) : an open-label, non-inferiority, randomised controlled trial

BACKGROUND: Before this study started, the standard postoperative chemotherapy regimen for stage II-III Wilms' tumour pretreated with chemotherapy was to include doxorubicin. However, avoidance of doxorubicin-related cardiotoxicity effects is important to improve long-term outcomes for childhood cancers that have excellent prognosis. We aimed to assess whether doxorubicin can be omitted safely fro