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Metabolically engineered baker’s yeast can be used to produce chiral amines through whole-cell bioconversion of prochiral ketones. This study investigates the modulation of the alanine-pyruvate metabolic node to enhance reductive amination, using the stereoselective conversion of benzylacetone to (S)-1-methyl-3-phenylpropylamine (MPPA) as a model reaction. Chromosomal integration of multiple copie
Coarctation of the aorta is a congenital heart anomalyinvolving constriction of an aortic segment, associated with wall thickening of media and the formationof overlapping infolding of neointimal tissue. For thefirst time it was described by Morgagni in 1760. Thispathology represents 5% -7% of all congenital heartdiseases, with an incidence of approximately 3 casesto 10 000 neonates1. The typical
Osteonecrosis (ON) is a common complication of glucocorticoid-based Hodgkin lymphoma (HL) treatment, but the natural evolution and prognosis of ON lesions remain poorly understood. We describe the radiological evolution of ON lesions identified in a Nordic population-based cohort of paediatric HL patients. Magnetic resonance images of suspected ON lesions were centrally reviewed to confirm ON diag
Digital innovation offers promising avenues for accessible, engaging, and user-friendly training solutions, crucial for promoting safety among manufacturing workers. However, optimizing these solutions demands a profound understanding of workers’ needs and preferences in interacting with these digital systems. The ongoing “DigiSafeMan” project aims to develop a prototype of a digital training tool
The Oslofjord subsea road tunnel is a unique environment in which the typically anoxic marine deep subsurface is exposed to oxygen. Concrete biodeterioration and steel corrosion in the tunnel have been linked to the growth of iron- and manganese-oxidizing biofilms in areas of saline water seepage. Surprisingly, previous 16S rRNA gene surveys of biofilm samples revealed microbial communities domina
Experimental data on analog performance of gate-all-around III-V vertical Tunnel Field-Effect Transistors (TFETs) and circuits are presented. The individual device shows a minimal subthreshold swing of 44 mV/dec and transconductance efficiency of 50 V−1 for current range of 9 nA/μm to 100 nA/μm and at a drain voltage of 100 mV. This TFET demonstrates translinearity between transconductance and dra
The Parkinson's disease (PD) home diary is frequently used in clinical trials to measure efficacy of medical treatments for motor fluctuations in advanced PD. This prospective study in fluctuating PD patients examines the validity of the diary for quantification of motor states in comparison to direct clinical observation. 51 patients (median age: 65 years, disease duration: 11 years) completed th
OBJECTIVES: The referrals of elderly for cardiac surgery are increasing. The aim of this retrospective study is to review the long-term survival and to identify causes of late death in elderly after cardiac surgery. DESIGN: Between 1990 and 1993, 130 octogenarians underwent cardiac surgery in our department. A majority (88%) had elective surgery. One hundred and nine patients (84%) were in New Yor
Cerebrospinal fluid (CSF) α-synuclein (α-syn) seed amplification assays (SAAs) can detect Lewy body pathology (LBP) with high accuracy but are invasive and costly. To address these challenges, this study evaluated a two-step workflow combining prescreening via smell-function testing with confirmatory CSF α-syn SAA testing only in individuals with reduced smell, for predicting postmortem LBP status
Recent years’ progress in the development of Continuous Glucose Monitors (CGM) has made rich well-sampled glucose data readily available. Reliable, frequent measurements are of outmost importance for the emerging closed-loop control of diabetic plasma glucose. However, these sensors do not measure the variable of primary interest - plasma glucose, but a delayed signal - the interstitial glucose. T
The healthy cornea is transparent, however, disease can affect its structure, rendering it more or less opaque. The ability to assess the clarity of the cornea objectively could thus be of considerable interest for keratoconus patients. It has previously been suggested that densitometry can be used to diagnose early keratoconus, and that the values of densitometry variables increase with increasin
KONSTNÄRLIGT KANDIDATPROGRAM I MUSIK | SYMFONIORKESTERINSTRUMENT Hållpunkter för din ansökan Anmäl dig till programmet på antagning.seAnmälningsperiod: 1 december 2025 – 15 januari 2026. Delprov 1. Ladda upp dina arbetsprover senast 21 januari 2026. En jurygrupp bedömer arbetsproverna och godkända sökande går vidare till delprov 2. Kallelsen till delprov 2 skickas till den mejladress du angav vid
KONSTNÄRLIGT KANDIDATPROGRAM I MUSIK | SYMFONIORKESTERINSTRUMENT Hållpunkter för din ansökan Anmäl dig till programmet på antagning.seAnmälningsperiod: 1 december 2025 – 15 januari 2026. Delprov 1. Ladda upp dina arbetsprover senast 21 januari 2026. En jurygrupp bedömer arbetsproverna och godkända sökande går vidare till delprov 2. Kallelsen till delprov 2 skickas till den mejladress du angav vid
KONSTNÄRLIGT KANDIDATPROGRAM I MUSIK | SYMFONIORKESTERINSTRUMENT Hållpunkter för din ansökan Anmäl dig till programmet på antagning.seAnmälningsperiod: 1 december 2025 – 15 januari 2026. Delprov 1. Ladda upp dina arbetsprover senast 21 januari 2026. En jurygrupp bedömer arbetsproverna och godkända sökande går vidare till delprov 2. Kallelsen till delprov 2 skickas till den mejladress du angav vid
KONSTNÄRLIGT KANDIDATPROGRAM I MUSIK | SYMFONIORKESTERINSTRUMENT Hållpunkter för din ansökan Anmäl dig till programmet på antagning.seAnmälningsperiod: 1 december 2025 – 15 januari 2026. Delprov 1. Ladda upp dina arbetsprover senast 21 januari 2026. En jurygrupp bedömer arbetsproverna och godkända sökande går vidare till delprov 2. Kallelsen till delprov 2 skickas till den mejladress du angav vid
KONSTNÄRLIGT KANDIDATPROGRAM I MUSIK | SYMFONIORKESTERINSTRUMENT Hållpunkter för din ansökan Anmäl dig till programmet på antagning.seAnmälningsperiod: 1 december 2025 – 15 januari 2026. Delprov 1. Ladda upp dina arbetsprover senast 21 januari 2026. En jurygrupp bedömer arbetsproverna och godkända sökande går vidare till delprov 2. Kallelsen till delprov 2 skickas till den mejladress du angav vid
KONSTNÄRLIGT KANDIDATPROGRAM I MUSIK | SYMFONIORKESTERINSTRUMENT Hållpunkter för din ansökan Anmäl dig till programmet på antagning.seAnmälningsperiod: 1 december 2025 – 15 januari 2026. Delprov 1. Ladda upp dina arbetsprover senast 21 januari 2026. En jurygrupp bedömer arbetsproverna och godkända sökande går vidare till delprov 2. Kallelsen till delprov 2 skickas till den mejladress du angav vid
