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The purpose of this phase II randomized trial was to evaluate the effect and safety of interferon-2a (IFN) in combination with extended dosing rituximab in patients with symptomatic, advanced indolent lymphoma responding to a standard single course of rituximab. Totally 123 patients were treated with rituximab 375mg/m2 once weekly for 4 weeks leading to 14 complete response (CR; 11%), 56 partial r

Factors contributing to valuable development assistance are often perceived as a "black box," due to heterogeneity of development aid motives. This research brings out that too often, the value of aid is assessed from the perspectives of the donors rather than from its recipients. Therefore, this thesis takes a focus to study the recipient's perspectives for valuable development assi

Using a sample of large US firms, this study shows that blockholders in combination with liquidity can contribute positively to innovation (R&D investments). We contribute to the literature on managerial myopia that has focused mainly on large owners and their type (short-term/long-term). Our results are in line with recent theoretical studies arguing that blockholders in combination with mark

Objectives. Cirrhosis is a well-known risk factor for hepatocellular cancer, but the true risk in autoimmune hepatitis (AIH) is scarcely studied. Other cancers may arise after prolonged use of immune-modulating drugs. The aim of this study was to investigate the cancer risk in a large cohort of AIH patients. Material and methods. Six hundred and thirty-four Swedish patients in a well-defined cohor

In his paper Hypnosis Reconsidered, Resituated, and Redefined (JSE 26(2):297–327), Adam Crabtree, a distinguished expert in the history of hypnosis, maintains that contemporary hypnosis research suffers from conceptual disorder. In his words, he attempts to redefi ne hypnosis in order to provide a stronger ground for future research. We find that his proposed reconsideration of hypnosis as a form

Kärnvapen är i allra högsta grad kraftfulla militära och politiska vapen. På grund av detta är frågan om dess legalitet i internationell rätt sedan länge omdebatterad. När frågan ställdes inför den internationella domstolen myntades ett nytt begrepp; ”statlig överlevnad”. Domstolens användning av begreppet väckte frågan om statlig överlevnad utgör ett exceptionellt undantag som kan rättfärdiga vå

Today more and more people choose to live a life as cohabitants instead of being married. In today’s Cohabitees Act from 2003 the cohabitants have an lower legal status than marriage. The same thing applies for cohabitants provision for surviving. Cohabitants have no legal right of inheritance when one cohabitant dies. The purpose of this essay is to investigate the legal system in Sweden and Nor

This research paper examines whether the prevention of Member State's taxes avoidance can justify hindrance of the TFEU freedoms. The legal research performed leads to the conclusion that, despite the fact that such justification existed in the past in the ECJ's case law, it was de facto abolished within the ambit of Case C-196/04 Cadbury Schweppes, since in this case the ECJ restricted t

Microsoft Word - ASG Rapid brain change and long term outcomes 2019-2019 ENG.docx ASG Rapid brain change and long- term outcomes We continue to learn new skills and develop our abilities throughout our life. Modern neuroimaging methods let us look inside the brain and observe how and where changes occur as an effect of experience. In the recent past, researchers have come to realize that learning

https://www.pi.lu.se/en/sites/pi.lu.se.en/files/asg_rapid_brain_change_and_long_term_outcomes_2019-2019_eng.pdf - 2026-05-16

The photoinduced electron-transfer reactions in a Mn-2(II.II)-R-II-NDI triad (1) ([Mn-2(bpmp)(OAc)(2)](+), bpmp = 2,6-bis[bis(2-pyridylmethyl)aminomethyl]-4-methyiphenolate and OAc = acetate, R-II = trisbipyridine ruthenium(II), and NDI = naphthalenediimide) have been studied by time-resolved optical and EPR spectroscopy. Complex 1 is the first synthetically linked electron donor-sensitizer-accept

Abstract Objectives. To investigate whether coronary microemboli have long-term effects on left ventricular (LV) function in an experimental model. Furthermore, to determine if first-pass perfusion and late gadolinium enhancement (LGE) patterns differs between small- and large-sized microemboli. Design. Six pigs underwent left anterior descending (LAD)-coronary microembolization with small-sized (

AIM: To evaluate long-term endocrine and exocrine pancreatic function, quality of life and health care costs after mild acute pancreatitis and severe acute pancreatitis (SAP). METHODS: Patients prospectively included in 2001-2005 were followed-up after 42 (36-53) mo. Pancreatic function was evaluated with laboratory tests, the oral glucose tolerance test (OGTT), fecal elastase-1 and a questionnair

Förmannaansvar (command responsibility) är en form av straffansvar som utvecklats till största delen under 1900-talet och ger möjlighet att åtala militära befälhavare och andra överordnade för krigsbrott samt brott mot mänskligheten genom att bevisa tre rekvisit. Inledningsvis måste befälhavaren ha effektiv kontroll över den underordnade som begått brottet. Vidare krävs att befälhavaren innehar enCommand responsibility is a mode of criminal responsibility that developed mostly during the 20th century and provides the opportunity to charge military commanders and other superiors for war crimes and crimes against humanity committed by their subordinates by proving three criteria. To begin with, the commander must have exercised effective control over the subordinate, moreover the commander m

Studies showing that large-scale public health interventions in early life have lasting economic consequences are still scarce and rarely disclose the mechanisms. Being born in a hospital versus having a traditional birth attendant at home represents the most common early life policy change worldwide. Knowing the consequences of this policy is also important given the ongoing enlargement of matern

CONTEXT: Whether multisystem morbidity in Cushing's disease (CD) remains elevated during long-term remission is still undetermined. OBJECTIVE: To investigate comorbidities in patients with CD. DESIGN, SETTING, AND PATIENTS: A retrospective, nationwide study of patients with CD identified in the Swedish National Patient Register between 1987 and 2013. Individual medical records were reviewed to ver

The discussions in this chapter should be viewed as a limited contribution to the debate on how to introduce the right to equal treatment through legislation. In the coming pages, I shall use a case study to demonstrate the differences between rights which emerge organically from below and work bottom up and rights which are introduce through political pressure from above and work top down. This s

Frånvaron av en central mekanism för att försäkra reglers efterlevnad inom folkrätten har ofta väckt frågan om varför reglerna faktiskt efterlevs. Flera möjliga motiv och hela teorier har föreslagits som förklaringar. Den här uppsatsen är ett försök att demonstrera hur folkrätten kan upprätthållas även om det skulle vara så att det folkrättsliga systemets består av rationella egennyttiga aktörer. The absence of a central enforcement mechanism in international law has often raised the question of why international law is complied with. Several possible motives and whole theories have been put forth to explain it. This thesis is an attempt at demonstrating how international law can be upheld even if the actors within the legal system are self-interested rational actors. The model is construc

Några utav de vanligaste orsakerna till att en brand uppkom mellan 2010 och 2020 var ”bränder som medvetet startades” samt ”bränder som startats av gnistor vid tågbromsning”. Av den totala mängden bränder som uppkom stod tågbromsning för cirka 1.1 % av dem och den anledning som stod för absolut störst andel bränder var ”bränder startade utav okänd anledning” vilket stod för 43%. KlimatförändringaForest fires can start in a variety of ways. "Fires started deliberately" and "fires started by sparks generated from a train braking" were two of the most common causes of fires between 2010 and 2020. Train braking accounted for 1.1% of all fires, whereas fires created by unknown reasons accounted for 43% of all fires. The climate is expected to change in the future, and sinc

Support for managers This page provides support and information on the recruitment process for researchers and technical and administrative staff (TA), who are appointed in accordance with the Swedish Employment Protection Act (LAS). Recruiting new employees is a strategically important decision and often a major investment for the organization. A well-executed recruitment process increases the ch

https://www.hr-pages.lu.se/recruitment-lund-university/recruitment-researchers-and-technical-and-administrative-staff-ta - 2026-05-15

BACKGROUND Men and women with type 1 long QT syndrome (LQT1) exhibit time-dependent differences in the risk for cardiac events. OBJECTIVE We hypothesized that sex-specific risk for LQT1 is related to the location and function of the disease-causing mutation in the KCNQ1 gene. METHODS The risk for life-threatening cardiac events (comprising aborted cardiac arrest [ACA] or sudden cardiac death [SCD]